Abstract: A memory stores R-R interval (RRI) data collected from a patient over a time interval and oxygen saturation (SaO2) data collected from the patient over the time interval. A processor is programmed to analyze the SaO2 data to identify desaturation events, analyze the RRI data to identify dips, utilize the dips to construct a RRI dip index measure of RRI dips per unit time over the time interval, determine a number of desaturations above a predefined threshold, determine an oxygen desaturation index (ODI), and utilize the RRI dip index and the ODI to provide results indicative of a risk of sleep-disordered breathing (SDB) for the patient.

Abstract: Two programs measure upper airway resistance using Resistance=Pressure/Flow. Raw flow and pressure data is divided into breaths and time adjusted so each breath starts with the value zero. Each breath is graphed as flow in the y-axis and time in the x-axis. The slope between points Flow=0 and Flow=0.20 is calculated. The resistance is the inverse of the slope. The second program determines whether a breath is flow limited or not. It also uses the flow and time data to perform a curve fitting to describe the flow-time in meaningful polynomial function F (P)=A t3+B t2+Ct+D. The derivative of this function is F?=3At2+2Bt+C. If the value of the derivative F? at maximum flow is less than or equal zero, then it is a flow limited breath, otherwise, it is non flow limited breath. Also, the need for a pressure-monitoring catheter is obviated.

Abstract: Application of synthetic or naturally occurring lung surfactant to the posterior pharyngeal region prior to a period of sleep significantly reduces episodes of sleep disturbance resulting in apnea or hypopnea. The present invention provides lung surfactant in a convenient applicator container for easy use and storage. Incidents of oxygen desaturation are reduced, thereby lowering the risks of apnea-associated pathologies.

Abstract: Application of synthetic or naturally occurring lung surfactant to the posterior pharyngeal region prior to a period of sleep significantly reduces episodes of sleep disturbance resulting in apnea or hypopnea. The present invention provides lung surfactant in a convenient applicator container for easy use and storage. Incidents of oxygen desaturation are reduced, thereby lowering the risks of apnea-associated pathologies.

Abstract: Application of synthetic or naturally occurring lung surfactant to the posterior pharyngeal region prior to a period of sleep significantly reduces episodes of sleep disturbance resulting in apnea or hypopnea. The present invention provides lung surfactant in a convenient applicator container for easy use and storage. Incidents of oxygen desaturation are reduced, thereby lowering the risks of apnea-associated pathologies.