Patents by Inventor M. Suzanne Bradshaw

M. Suzanne Bradshaw has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Yeast-Bacteria shuttle vector
    Patent number: 6897353
    Abstract: The functional analysis of genes frequently requires the manipulation of large genomic regions. A yeast-bacteria shuttle vector is described, that can be used to clone large regions of DNA by homologous recombination. The important feature of present invention is the presence of the a bacterial replication origin, which allows large DNA insert capacity. The utility of this vector lies in its ability to isolate, manipulate and maintain large fragments in bacteria and yeast, allowing for mutagenesis by yeast genetics and simplified preparation of plasmid DNA in bacteria.
    Type: Grant
    Filed: December 4, 2000
    Date of Patent: May 24, 2005
    Assignee: Yale University
    Inventors: M. Suzanne Bradshaw, Jacques A. Bollekens, Frank H. Ruddle
  • New yeast-bacteria shuttle vector
    Publication number: 20020132348
    Abstract: The functional analysis of genes frequently requires the manipulation of large genomic regions. A yeast-bacteria shuttle vector is described, that can be used to clone large regions of DNA by homologous recombination. The important feature of present invention is the presence of the a bacterial replication origin, which allows large DNA insert capacity. The utility of this vector lies in its ability to isolate, manipulate and maintain large fragments in bacteria and yeast, allowing for mutagenesis by yeast genetics and simplified preparation of plasmid DNA in bacteria.
    Type: Application
    Filed: December 4, 2000
    Publication date: September 19, 2002
    Inventors: M. Suzanne Bradshaw, Jacques A. Bollekens, Frank H. Ruddle
  • Yeast-bacteria shuttle vector
    Patent number: 6221588
    Abstract: The functional analysis of genes frequently requires the manipulation of large genomic regions. A yeast-bacteria shuttle vector is described, that can be used to clone large regions of DNA by homologous recombination. The important feature of present invention is the presence of the a bacterial replication origin, which allows large DNA insert capacity. The utility of this vector lies in its ability to isolate, manipulate and maintain large fragments in bacteria and yeast, allowing for mutagenesis by yeast genetics and simplified preparation of plasmid DNA in bacteria.
    Type: Grant
    Filed: June 10, 1998
    Date of Patent: April 24, 2001
    Assignee: Yale University
    Inventors: M. Suzanne Bradshaw, Jacques A. Bollekens, Frank H. Ruddle
  • Yeast-bacteria shuttle vector
    Patent number: 5866404
    Abstract: The functional analysis of genes frequently requires the manipulation of large genomic regions. A yeast-bacteria shuttle vector is described, that can be used to clone large regions of DNA by homologous recombination. The important feature of present invention is the presence of the a bacterial replication origin, which allows large DNA insert capacity. The utility of this vector lies in its ability to isolate, manipulate and maintain large fragments in bacteria and yeast, allowing for mutagenesis by yeast genetics and simplified preparation of plasmid DNA in bacteria.
    Type: Grant
    Filed: December 6, 1996
    Date of Patent: February 2, 1999
    Assignee: Yale University
    Inventors: M. Suzanne Bradshaw, Jacques A. Bollekens, Frank H. Ruddle