Abstract: The present disclosure relates to biomarker profiles and their use to predict a subject's response to an immunomodulatory treatment. Biomarkers in these profiles include cytokines and other proteins associated with the interleukin 1 family and the type 1 interferon family. Particular biomarkers include interleukin (IL)-2, soluble IL-2 receptor alpha (sIL-2RA), IL-5, IL-6, IL-9, IL-10, IL-18, IL-18 binding protein (IL-18BP), IL-18 receptor 1 (IL-18R1), IL-18 receptor accessory protein (IL-18RAP), IL-22, C-type lectin-like receptor (CD161), CD56, interferon gamma (IFN?), granulocyte macrophage colony stimulating factor (GM-CSF), serum amyloid A (SAA), and C-reactive protein (CRP). Particular biomarkers also include populations of cells including CD161+ cells and CD56+dim cells. The biomarker profiles can be used to predict a subject's responsiveness to an immunomodulatory treatment (e.g.

Abstract: A three-dimensional transformable toy having a body with a first surface and a second surface and having a hollow cavity formed therein. A flexible fill material is positioned between the first and second surfaces. The toy also has expandable/contractable member positioned between the first and second surfaces and which surrounds an opening leading to the hollow cavity. The expandable/contractable member permits the opening to expand in size and contract in size as the body switches between the first and second configurations. The expandable/contractable member further creates a relatively flat bottom surface which allows the toy to stand upright in both the first and second configurations.

Abstract: An apparatus, system, and method are directed towards enabling auditing of network vulnerabilities from multiple network vantage points virtually simultaneously. Multiple network vantage points may include, but are not limited to, remote/branch enterprise sites, devices on an enterprise perimeter, on either side of a security perimeter, and even through the security perimeter. In one embodiment, an auditor performs reflected audits thereby extending auditing of network vulnerabilities to provide a comprehensive 360 degree audit of internal, external, and remote enterprise network sites. In one embodiment, the present invention may be implemented employing a single auditing device, and one or more audit extension devices that are configured to extend the auditing device's audit reach. The auditing device and one or more audit extension devices may communicate using an encrypted network channel through a security perimeter and/or across multiple networks.

Abstract: An apparatus, system, and method are directed towards enabling auditing of network vulnerabilities from multiple network vantage points virtually simultaneously. Multiple network vantage points may include, but are not limited to, remote/branch enterprise sites, devices on an enterprise perimeter, on either side of a security perimeter, and even through the security perimeter. In one embodiment, an auditor performs reflected audits thereby extending auditing of network vulnerabilities to provide a comprehensive 360 degree audit of internal, external, and remote enterprise network sites. In one embodiment, the present invention may be implemented employing a single auditing device, and one or more audit extension devices that are configured to extend the auditing device's audit reach. The auditing device and one or more audit extension devices may communicate using an encrypted network channel through a security perimeter and/or across multiple networks.

Abstract: A laminate sheet article including: a core including an electrical semi-conductor or an electrical conductor; and a continuous glass clad layer on at least four of six sides the core of the sheet article. Also disclosed is an apparatus for making a sheet laminate article as defined herein. Also disclosed is a method of making and using the article.

Abstract: A steel wall stud has a rear wall, two parallel side walls, each side wall having a front end wall that projects away from interior cavity formed by the rear and side walls.

Abstract: A foldable chair has frames connected to one another by cross supports, bases connected to the frames by base supports and frame supports, with springs secured between the base supports and frame supports to allow for back and forth movement of the frames when a user is seated in the chair. The foldable chair includes a pliant membrane providing a seating surface for supporting the user.

Abstract: A steel wall stud has a rear wall, two parallel side walls, each side wall having a front end wall that projects away from interior cavity formed by the rear and side walls.

Abstract: Data is obtained specifying a measure of a data set to be analyzed by human experts and allotted time for analysis completion. Based on same, a schedule is created for a primary meeting of human experts, whose aim is to analyze the data. The meeting is evaluated to create rate estimates for hypothetical meeting partitions; and, if the primary meeting is not adhering to schedule and/or can be speeded up, the meeting partitions are simulated until a partitioning scheme is determined that can restore the meeting to schedule and/or speed it up. In another aspect, a model of focus of attention of each member of a group of individuals engaged in an activity requiring cooperation is dynamically updated, and a cooperation index is determined based on the model of focus of attention, an interaction graph, and at least one physiological parameter of at least one of the members.

Abstract: A foldable chair has frames connected to one another by cross supports, bases connected to the frames by base supports and frame supports, with springs secured between the base supports and frame supports to allow for back and forth movement of the frames when a user is seated in the chair. The foldable chair includes a pliant membrane providing a seating surface for supporting the user.

Abstract: A laminate sheet article including: a core including an electrical semi-conductor or an electrical conductor; and a continuous glass clad layer on at least four of six sides the core of the sheet article. Also disclosed is an apparatus for making a sheet laminate article as defined herein. Also disclosed is a method of making and using the article.

Abstract: A biological sterilization indicator device is provided. The device comprises a body, a plurality of test microorganisms, and an oxygen-modulated first fluorescent sensor. The body comprises a first layer attached to a second layer, forming at least one isolatable microchamber and at least one primary passageway that provides fluidic communication between ambience and the at least one microchamber. The microchamber has an isolated volume of about 0.5 microliters to about 9.5 microliters. The plurality of test microorganisms and the oxygen-modulated first fluorescent sensor are disposed in the microchamber. A method of using the device to determine the effectiveness of a sterilization process is also provided.

Abstract: Augmented reality (AR) based component replacement and maintenance may include receiving a first wireless signal from a pair of AR glasses worn by a user. An image of a component viewed by the user may be analyzed and compared to a plurality of images of components stored in a database that includes information associated with the plurality of images of the components. Based on a match of the image of the component viewed by the user to one of the plurality of images of the components stored in the database, the component viewed by the user may be identified. An inventory of the identified component may be analyzed to determine whether a supplier includes the identified component in stock, and in response to a determination that the supplier includes the identified component in stock, an estimated time of delivery of the identified component to the user may be determined.

Abstract: A similarity determination method, system, and computer program product, including using a description of companies for making a list of query entities, calculating a set of similar companies for each company on the list of query entities, employing a voting scheme to rank the results of the calculating, ordering a final set of the results based on the voting scheme and presenting them back to the user as a first ranked list, iteratively repeating the calculating by adding a second set of new companies and recalculating a second ranked list of recommended companies based on the updated query list, combining the first ranked list and the second ranked into a single set of companies of a combined list while remembering which of the first ranked list and the second ranked list from which each company originated, and visualizing the combined list based on which original list the companies came from. The technique can be extended to an arbitrary number of lists.

Abstract: An apparatus, system, and method are directed towards enabling auditing of network vulnerabilities from multiple network vantage points virtually simultaneously. Multiple network vantage points may include, but are not limited to, remote/branch enterprise sites, devices on an enterprise perimeter, on either side of a security perimeter, and even through the security perimeter. In one embodiment, an auditor performs reflected audits thereby extending auditing of network vulnerabilities to provide a comprehensive 360 degree audit of internal, external, and remote enterprise network sites. In one embodiment, the present invention may be implemented employing a single auditing device, and one or more audit extension devices that are configured to extend the auditing device's audit reach. The auditing device and one or more audit extension devices may communicate using an encrypted network channel through a security perimeter and/or across multiple networks.

Abstract: A steel wall stud has a rear wall, two parallel side walls, each side wall having a front end wall that projects away from interior cavity formed by the rear and side walls.

Abstract: An apparatus, system, and method are directed towards enabling auditing of network vulnerabilities from multiple network vantage points virtually simultaneously. Multiple network vantage points may include, but are not limited to, remote/branch enterprise sites, devices on an enterprise perimeter, on either side of a security perimeter, and even through the security perimeter. In one embodiment, an auditor performs reflected audits thereby extending auditing of network vulnerabilities to provide a comprehensive 360 degree audit of internal, external, and remote enterprise network sites. In one embodiment, the present invention may be implemented employing a single auditing device, and one or more audit extension devices that are configured to extend the auditing device's audit reach. The auditing device and one or more audit extension devices may communicate using an encrypted network channel through a security perimeter and/or across multiple networks.

Abstract: In an approach to determining an introduction of a user in a meeting, one or more computer processors retrieve a document containing information associated with a user, wherein the document includes one or more fragments describing the user. The one or more computer processors determine an audience of a meeting associated with the user. The one or more computer processors determine a description of the meeting. The one or more computer processors prioritize one or more of the one or more fragments, based, at least in part, on the audience of the meeting and on the description of the meeting. The one or more computer processors select one or more of the one or more fragments for the introduction of the user in the meeting, based, at least in part, on the prioritization of the one or more fragments.

Abstract: A sensing device, such as a user-wearable device (UWD) worn by a user of a touchscreen, may provide kinematic data of the sensing device or UWD and/or identification data of the user to a processor that operates the touchscreen. Such data may allow the processor to perform a number of user-touchscreen interactions, such as displaying user-specific windows or menus, processing user-manipulation of displayed objects, and determining which hand of a user performs a touch event, just to name a few examples.