Patents by Inventor Ma Carmen Onrubia Miguel

Ma Carmen Onrubia Miguel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Intermediate compounds for the preparation of mirtazapine and production methods thereof
    Patent number: 7265223
    Abstract: The present invention is directed to intermediate compounds of mirtazapine and methods for obtaining same. A method is described for obtaining (±)-3-phenyl-1-methylpiperazine, an important intermediate for obtaining mirtazapine, which is based on imposing a cyclization reaction, in the presence of a reducing agent, on new compounds of general formula (1) in which Z is a leaving group capable of undergoing a nucleophilic displacement. A method is also described for obtaining the new compounds of formula (1).
    Type: Grant
    Filed: September 14, 2001
    Date of Patent: September 4, 2007
    Assignee: Medichem, S.A.
    Inventors: Jordi Bosch i Lladó, Pelayo Camps García, Juan Contreras Lascorz, Ma Carmen Onrubia Miguel
  • Intermediate compounds for the preparation of mirtazapine and the production methods thereof
    Publication number: 20040236107
    Abstract: Intermediate compounds for the preparation of mirtazapine and obtention methods thereof.
    Type: Application
    Filed: March 4, 2004
    Publication date: November 25, 2004
    Inventors: Jordi Bosch i Llado, Pelayo Camps Garcia, Juan Contreras Lascorz, Ma Carmen Onrubia Miguel
  • Method for obtaining polymorph a from doxazosine mesylate
    Patent number: 6525195
    Abstract: The invention discloses a process for the preparation of the polymorh A of doxazosin meylate, consisting essentially of reacting doxazosin base with methanesulfonic acid in a mixture of solvents containing an alcohol and a chlorinated solvent, subsequently removing the chlorinated solvent by distillation and precipitating the desired product in an alcohol, after heating the suspension formed to the reflux temperature of the solvent.
    Type: Grant
    Filed: August 14, 2001
    Date of Patent: February 25, 2003
    Assignee: Medichem, S.A.
    Inventors: Carmen Arnalot I Aguilar, Jordi Bosch I Lladó, Ma Carmen Onrubia Miguel