Patents by Inventor Ma-Li Siu

Ma-Li Siu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9872879
    Abstract: The present invention provides a process for the preparation of Plectranthus amboinicus extracts using a stirring separation method. The present invention also relates to a pharmaceutical composition comprising the Plectranthus amboinicus crude extract and/or extract for treating skin disorders, including enhancing the healing of wounds, especially in diabetic patients.
    Type: Grant
    Filed: April 29, 2013
    Date of Patent: January 23, 2018
    Assignee: DEVELOPMENT CENTER FOR BIOTECHNOLOGY
    Inventors: Rey-Yuh Wu, Yuh-Shan Chung, Yu-Yuan Wu, Ma-Li Siu, Chin-Wen Hsiao
  • Patent number: 9474777
    Abstract: An extract of Graptopetalum paraguayense prepared by a method that includes: extracting a Graptopetalum paraguayense (GP) starting material with an alcoholic solvent to produce an alcoholic extract and a residue; separating the residue from the alcoholic extract; extracting the residue with an aqueous dimethyl sulfoxide (DMSO) solvent to produce a DMSO extract; subjecting the DMSO extract to ultrafiltration using a filter having a selected molecular weight cutoff; drying a fraction retained by the filter to obtain the extract of Graptopetalum paraguayense. Uses of an extract of Graptopetalum paraguayense for the treatment or prevention of liver fibrosis, hepatic cirrhosis, liver cancer, recurrence of liver fibrosis after surgery, or recurrence of liver cancer after surgery.
    Type: Grant
    Filed: December 30, 2013
    Date of Patent: October 25, 2016
    Assignee: Development Center for Biotechnology
    Inventors: Yuh-Shan Chung, Ma-Li Siu, Tzung-Hsien Lai, Szu-Chien Yeh
  • Publication number: 20150182572
    Abstract: An extract of Graptopetalum paraguayense prepared by a method that includes: extracting a Graptopetalum paraguayense (GP) starting material with an alcoholic solvent to produce an alcoholic extract and a residue; separating the residue from the alcoholic extract; extracting the residue with an aqueous dimethyl sulfoxide (DMSO) solvent to produce a DMSO extract; subjecting the DMSO extract to ultrafiltration using a filter having a selected molecular weight cutoff; drying a fraction retained by the filter to obtain the extract of Graptopetalum paraguayense. Uses of an extract of Graptopetalum paraguayense for the treatment or prevention of liver fibrosis, hepatic cirrhosis, liver cancer, recurrence of liver fibrosis after surgery, or recurrence of liver cancer after surgery.
    Type: Application
    Filed: December 30, 2013
    Publication date: July 2, 2015
    Applicant: DEVELOPMENT CENTER FOR BIOTECHNOLOGY
    Inventors: Yuh-Shan Chung, Ma-Li Siu, Tzung-Hsien Lai, Szu-Chien Yeh
  • Publication number: 20130309337
    Abstract: The present invention provides a process for the preparation of Plectranthus amboinicus extracts using a stirring separation method. The present invention also relates to a pharmaceutical composition comprising the Plectranthus amboinicus crude extract and/or extract for treating skin disorders, including enhancing the healing of wounds, especially in diabetic patients.
    Type: Application
    Filed: April 29, 2013
    Publication date: November 21, 2013
    Applicant: DEVELOPMENT CENTER FOR BIOTECHNOLOGY
    Inventors: REY-YUH WU, YUH-SHAN CHUNG, YU-YUAN WU, MA-LI SIU, CHIN-WEN HSIAO
  • Patent number: 8449924
    Abstract: The present invention provides a process for the preparation of Plectranthus amboinicus extracts using a stirring separation method. The present invention also relates to a pharmaceutical composition comprising the Plectranthus amboinicus crude extract and/or extract for treating skin disorders, including enhancing the healing of wounds, especially in diabetic patients.
    Type: Grant
    Filed: August 29, 2007
    Date of Patent: May 28, 2013
    Assignee: Development Center for Biotechnology
    Inventors: Rey-Yuh Wu, Yuh-Shan Chung, Yu-Yuan Wu, Ma-Li Siu, Chin-Wen Hsiao
  • Patent number: 8247004
    Abstract: The present invention provides a pharmaceutical composition for treating skin disorders, including enhancing the healing of wounds for diabetic patients. Specifically, this invention relates to the use of the extracts of Plectranthus amboinicus and Centella asiatica for improving skin disorders, including enhancing the healing of wounds for diabetic patients, and a pharmaceutical composition comprising the extracts of Plectranthus amboinicus and Centella asiatica as well as a wound dressing comprising the same. The invention also provides a method for preparing the crude extract and extract of Plectranthus amboinicus.
    Type: Grant
    Filed: June 15, 2011
    Date of Patent: August 21, 2012
    Assignee: Development Center for Biotechnology
    Inventors: Rey-Yuh Wu, Yuh-Shan Chung, Yu-Yuan Wu, Ma-Li Siu, Hung-Jen Huang, Chin-Wen Hsiao
  • Publication number: 20120009281
    Abstract: The present invention provides a pharmaceutical composition for treating skin disorders, including enhancing the healing of wounds for diabetic patients. Specifically, this invention relates to the use of the extracts of Plectranthus amboinicus and Centella asiatica for improving skin disorders, including enhancing the healing of wounds for diabetic patients, and a pharmaceutical composition comprising the extracts of Plectranthus amboinicus and Centella asiatica as well as a wound dressing comprising the same. The invention also provides a method for preparing the crude extract and extract of Plectranthus amboinicus.
    Type: Application
    Filed: June 15, 2011
    Publication date: January 12, 2012
    Inventors: Rey-Yuh WU, Yuh-Shan Chung, Yu-Yuan Wu, Ma-Li Siu, Hung-Jen Huang, Chin-Wen Hsiao
  • Patent number: 7985431
    Abstract: The present invention provides a pharmaceutical composition for treating skin disorders, including enhancing the healing of wounds for diabetic patients. Specifically, this invention relates to the use of the extracts of Plectranthus amboinicus and Centella asiatica for improving skin disorders, including enhancing the healing of wounds for diabetic patients, and a pharmaceutical composition comprising the extracts of Plectranthus amboinicus and Centella asiatica as well as a wound dressing comprising the same. The invention also provides a method for preparing the crude extract and extract of Plectranthus amboinicus.
    Type: Grant
    Filed: November 28, 2006
    Date of Patent: July 26, 2011
    Assignee: Development Center for Biotechnology
    Inventors: Rey-Yuh Wu, Yuh-Shan Chung, Yu-Yuan Wu, Ma-Li Siu, Hung-Jen Huang, Chin-Wen Hsiao
  • Publication number: 20090060985
    Abstract: The present invention provides a process for the preparation of Plectranthus amboinicus extracts using a stirring separation method. The present invention also relates to a pharmaceutical composition comprising the Plectranthus amboinicus crude extract and/or extract for treating skin disorders, including enhancing the healing of wounds, especially in diabetic patients.
    Type: Application
    Filed: August 29, 2007
    Publication date: March 5, 2009
    Applicant: DEVELOPMENT CENTER FOR BIOTECHNOLOGY
    Inventors: Rey-Yuh Wu, Yuh-Shan Chung, Yu-Yuan Wu, Ma-Li Siu, Chin-Wen Hsiao
  • Publication number: 20070237841
    Abstract: The present invention provides a pharmaceutical composition for treating skin disorders, including enhancing the healing of wounds for diabetic patients. Specifically, this invention relates to the use of the extracts of Plectranthus amboinicus and Centella asiatica for improving skin disorders, including enhancing the healing of wounds for diabetic patients, and a pharmaceutical composition comprising the extracts of Plectranthus amboinicus and Centella asiatica as well as a wound dressing comprising the same. The invention also provides a method for preparing the crude extract and extract of Plectranthus amboinicus.
    Type: Application
    Filed: November 28, 2006
    Publication date: October 11, 2007
    Inventors: Rey-Yuh Wu, Yuh-Shan Chung, Yu-Yuan Wu, Ma-Li Siu, Hung-Jen Huang, Chin-Wen Hsiao