Patents by Inventor Maanuel Martin Lomas

Maanuel Martin Lomas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Oligosaccharides for inhibiting the mitosis of astrocytes and tumoral cells of the nervous system, and methods for obtaining them
    Patent number: 5514658
    Abstract: A method for obtaining oligosaccharides starts with allylation of position (3') of .beta.-lactosides followed by controlled benzylation, which leads to perbenzylated and partially benzylated compounds. The latter are glycosylated at position 3, not benzylated, with a donor of .varies.-fucopyranosyl to yield protected trisaccharides. These and perbenzylated .beta.-Lactosides are deallylated and, later, are glycosylated with 2-azido-2-deoxy-.varies.-D-galactopyranosyl to yield protected tetrasaccharides and trisaccharides, respectively. The debenzylation of said products accompanied by the reduction of the azido group and simultaneous acetylation of the amino group produces intermediary products which, by O-deacetylation, leads respectively to the final tetrasaccharides and trisaccharides.
    Type: Grant
    Filed: July 12, 1993
    Date of Patent: May 7, 1996
    Assignee: Consejo Superior Investigaciones Cientificas
    Inventors: Fernando F. Santos Benito, Manuel Nieto Sampedro, Alfonso Fernandez-Mayoralas, Maanuel Martin Lomas