Patents by Inventor Maarten Chrispeels

Maarten Chrispeels has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lectin-derived progenitor cell preservation factors and methods of use
    Publication number: 20070280904
    Abstract: The invention relates to an isolated nucleic acid molecule that encodes a protein that is effective to preserve progenitor cells, such as hematopoietic progenitor cells. The nucleic acid comprises a sequence defined by SEQ ID NO:1, a homolog thereof, or a fragment thereof. The encoded protein has an amino acid sequence that comprises a sequence defined by SEQ ID NO:2, a homolog thereof, or a fragment thereof that contains an amino acid sequence TNNVLQVT. Methods of using the encoded protein for preserving progenitor cells in vitro, ex vivo, and in vivo are also described. The invention, therefore, include methods such as myeloablation therapies for cancer treatment wherein myeloid reconstitution is facilitated by means of the specified protein.
    Type: Application
    Filed: March 8, 2007
    Publication date: December 6, 2007
    Inventors: M. Colucci, Maarten Chrispeels, Jeffrey Moore
  • Progenitor cell preservation factors and methods for and products of their use
    Publication number: 20050181997
    Abstract: Disclosed is the FRIL family of progenitor cell preservation factors and nucleic acids encoding the same. FRIL family members preserve progenitor cells both in vivo and ex vivo. FRIL family members find use as therapeutics for alleviating and/or reducing the hematopoietic progenitor cell-depleting activity of many cancer therapeutics. FRIL family members are also useful for isolating rare, primitive progenitor cells.
    Type: Application
    Filed: March 16, 2005
    Publication date: August 18, 2005
    Applicants: Regents of the University of California, ImClone Systems Incorporated
    Inventors: M. Colucci, Maarten Chrispeels, Jeffrey Moore
  • Lectin-derived progenitor cell preservation factors and methods of use
    Publication number: 20050060779
    Abstract: The invention relates to an isolated nucleic acid molecule that encodes a protein that is effective to preserve progenitor cells, such as hematopoietic progenitor cells. The nucleic acid comprises a sequence defined by SEQ ID NO:1, a homolog thereof, or a fragment thereof. The encoded protein has an amino acid sequence that comprises a sequence defined by SEQ ID NO:2, a homolog thereof or a fragment thereof that contains an amino acid sequence TNNVLQVT. Methods of using the encoded protein for preserving progenitor cells in vitro, ex vivo, and in vivo are also described. The invention, therefore, include methods such as myeloablation therapies for cancer treatment wherein myeloid reconstitution is facilitated by means of the specified protein.
    Type: Application
    Filed: August 30, 2004
    Publication date: March 17, 2005
    Applicants: ImClone Systems Incorporated, Regents of the University of California
    Inventors: M. Colucci, Maarten Chrispeels, Jeffrey Moore
  • Maize aquaporins and uses thereof
    Patent number: 6313376
    Abstract: The invention provides isolated maize aquaporin nucleic acids and their encoded proteins. The present invention provides methods and compositions relating to altering aquaporin concentration and/or composition of plants. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions.
    Type: Grant
    Filed: August 11, 1999
    Date of Patent: November 6, 2001
    Assignees: Pioneer Hi-Bred International, Inc., The Regents of the University of California
    Inventors: Rudolf Jung, Francois Chaumont, Maarten Chrispeels