Patents by Inventor Maarten J. Chrispeels

Maarten J. Chrispeels has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the preparation of a composition based on 4-hydroxyproline and the uses thereof in the agronomical field
    Patent number: 8349770
    Abstract: The present invention relates to a method for the preparation of 4-hyroxy-L-proline or compositions with a high content of this aminoacid and the use thereof as agrochemical in the agronomical field and/or as a synthesis intermediate of chemical compounds.
    Type: Grant
    Filed: March 6, 2007
    Date of Patent: January 8, 2013
    Assignee: Arterra Bioscience S.R.L.
    Inventors: Maria Gabriella Colucci, Fabio Apone, Maarten J Chrispeels
  • Method for the Preparation of a Composition Based on 4-Hydroxyproline and the Uses Thereof in the Agronomical Field
    Publication number: 20090054241
    Abstract: The present invention relates to a method for the preparation of 4-hyroxy-L-proline or compositions with a high content of this aminoacid and the use thereof as agrochemical in the agronomical field and/or as a synthesis intermediate of chemical compounds.
    Type: Application
    Filed: March 6, 2007
    Publication date: February 26, 2009
    Inventors: Maria Gabriella Colucci, Fabio Apone, Maarten J. Chrispeels
  • Progenitor cell preservation factors and methods for and products of their use
    Patent number: 6991794
    Abstract: Disclosed are the FRIL family of progenitor cell preservation factors and nucleic acids encoding the same. FRIL family members preserve progenitor cells both in vivo and ex vivo. FRIL family members find use as therapeutics for alleviating and/or reducing the hematopoietic progenitor cell-depleting activity of many cancer therapeutics. FRIL family members are also useful for isolating rare, primitive progenitor cells.
    Type: Grant
    Filed: December 30, 1999
    Date of Patent: January 31, 2006
    Assignees: ImClone Systems Incorporated, The Regents of the University of California
    Inventors: M. Gabriella Colucci, Maarten J. Chrispeels, Jeffrey G. Moore
  • Lectin-derived progenitor cell preservation factor and methods of use
    Patent number: 6852321
    Abstract: The invention relates to an isolated nucleic acid molecule that encodes a protein that is effective to preserve progenitor cells, such as hematopoietic progenitor cells. The nucleic acid comprises a sequence defined by SEQ ID NO:1, a homolog thereof, or a fragment thereof. The encoded protein has an amino acid sequence that comprises a sequence defined by SEQ ID NO:2, a homolog thereof or a fragment thereof that contains an amino acid sequence TNNVLQVT. Methods of using the encoded protein for preserving progenitor cells in vitro, ex vivo, and in vivo are also described. The invention, therefore, include methods such as myeloablation therapies for cancer treatment wherein myeloid reconstitution is facilitated by means of the specified protein.
    Type: Grant
    Filed: October 29, 2001
    Date of Patent: February 8, 2005
    Assignees: ImClone Systems Incorporated, Regents of the University of California
    Inventors: M. Gabriella Colucci, Maarten J. Chrispeels, Jeffrey G. Moore
  • Nucleic acid encoding a lectin derived progenitor cell preservation factor
    Publication number: 20030049339
    Abstract: The invention relates to an isolated nucleic acid molecule that encodes a protein that is effective to preserve progenitor cells, such as hematopoietic progenitor cells. The nucleic acid comprises a sequence defined by SEQ ID NO:1, a homolog thereof, or a fragment thereof. The encoded protein has an amino acid sequence that comprises a sequence defined by SEQ ID NO:2, a homolog thereof or a fragment thereof that contains an amino acid sequence TNNVLQVT. Methods of using the encoded protein for preserving progenitor cells in vitro, ex vivo, and in vivo are also described. The invention, therefore, include methods such as myeloablation therapies for cancer treatment wherein myeloid reconstitution is facilitated by means of the specified protein.
    Type: Application
    Filed: October 29, 2001
    Publication date: March 13, 2003
    Applicant: Regents of the University of California
    Inventors: M. Gabriella Colucci, Maarten J. Chrispeels, Jeffrey G. Moore
  • Nucleic acid encoding a lectin-derived progenitor cell preservation factor
    Patent number: 6310195
    Abstract: The invention relates to an isolated nucleic acid molecule that encodes a protein that is effective to preserve progenitor cells, such as hematopoietic progenitor cells. The nucleic acid comprises a sequence defined by SEQ ID NO:1, a homolog thereof, or a fragment thereof. The encoded protein has an amino acid sequence that comprises a sequence defined by SEQ ID NO:2, a homolog thereof, or a fragment thereof that contains an amino acid sequence TNNVLQVT. Methods of using the encoded protein for preserving progenitor cells in vitro, ex vivo, and in vivo are also described. The invention, therefore, include methods such as myeloablation therapies for cancer treatment wherein myeloid reconstitution is facilitated by means of the specified protein.
    Type: Grant
    Filed: June 24, 1997
    Date of Patent: October 30, 2001
    Assignee: ImClone Systems Incorporated
    Inventors: M. Gabriella Colucci, Maarten J. Chrispeels, Jeffrey G. Moore