Abstract: The invention relates to a system for determining a cardiovascular parameter in a patient, wherein the system is adapted to work in conjunction with an extracorporeal blood treatment device (ECBTD) connectable to a patient's vascular system, wherein the ECBTD comprises a first circuit, the system comprising: a liquid-filled, second circuit thermally connected to the first circuit of the ECBTD via a heat exchanger, temperature changing means for generating a temperature change in the second circuit, temperature sensors TS2up and TS2down arranged in the second circuit upstream and downstream of the heat exchanger, respectively. A computer system connected to the temperature sensors and the temperature changing means is adapted to induce a temperature bolus within the first circuit of the ECBTD via the temperature changing means. From the individual temperature recorded as a function of time, temperature curves T2up(t) and T2down(t) are derived and evaluated.

Abstract: A kit includes the components lactic acid, insulin and glucose, and optionally one or more components selected from a glucagon inhibitor, an alpha-beta adrenergic blocker and an antidiabetic agent, for treating a glycolysis-dependent pathological condition in a human or animal. A treatment includes intravascular, in particular intravenous, delivery of the components lactic acid, insulin and glucose into the circulation of the human or animal to be treated to induce hypoglycemia and hyperlactatemia. The glycolysis-dependent pathological condition is selected from the group consisting of cancer, bacterial infection or parasite infection.