Abstract: A channel formed on a chip is opened without contaminating contents of the channel. Channels (107a) and (107b) provided on a substrate (103) are covered by pressing a lid (113) composed of a resin layer (102) and a plate-like lid (101) to a surface of the substrate (103). A fixing device has a retainer plate (104), which retains the plate-like lid (101) of a chip (112), a board (108) on which the substrate (103) is placed, and a screw (106). When covering the channels (107a) and (107b), the screw (106) is fastened and the lid (113) is pressed to the substrate (103) to be fixed. And, when opening an upper portion of the channels (107a) and (107b), the screw (106) is turned upward and a pressure is released, and the lid (113) is removed from the upper potion of the substrate (103).

Abstract: A microfluidic chip includes: a channel which is provided on a first portion of a surface of a substrate part, the channel being used for separating a substance subject to analysis by electrophoresis and adding a reaction reagent with a nozzle to the substance separated by electrophoresis; and an absorption region which is provided on a second portion of the surface of the substrate part, and which absorbs the reaction reagent, the second portion being different from the first portion.

Abstract: The present invention provides a method of automating the operation to peel and remove a lid part adhered and fixed to the top surface of a substrate part, which composes a lidded “microchip”, after subjecting a sample liquid to be analyzed to an operation for electrophoretic separation. After subjecting the liquid sample to be analyzed to a desired operation of electrophoretic separation by utilizing a channel formed in the lidded microchip, aqueous solvent contained in the electrophoretically separated liquid sample held in the channel is frozen, and the end of the lid part sealing the groove-shaped channel formed on the substrate part is lifted up at a predetermined speed while keeping the whole electrophoretically separated sample in the frozen state, and peeled and removed from the substrate part under a condition to maintain the bend of a predetermined radius of curvature.

Abstract: The present invention provides a technique for automating the operation to peel off and remove a lid seal part adhered and fixed to the top face of a substrate part constituting a lid-sealed “microchip” after subjecting a sample solution to be analyzed to electrophoretic separation. After subjecting sample solution to be analyzed to desired electrophoretic separation the by utilizing a channel formed in the lid-sealed microchip, the electrophoretically separated liquid sample held in the channel undergoes freezing of the aqueous solvent contained and then, while the whole electrophoretically separated liquid sample remains sustained in the frozen state, an end of the lid seal part used for sealing the top face of channel formed in the substrate part is lifted up at a predetermined speed so as to peel and remove it from the substrate part under a condition of maintaining a bend of a predetermined radius of curvature.

Abstract: Provided is a microchip including a substrate, a channel on the substrate, a lid sealing the channel, and an upper lid bonded to the lid. The lid is formed of an elastic material. The lid is detachable from the substrate. The upper lid is formed of a material harder than the elastic material. The area of the upper lid surface that is bonded to the lid is smaller than the area of the upper surface of the lid.

Abstract: With the object of realizing a microchip that allows drying and fixing of a substance that is the object of analysis in a shorter time while maintaining the separation capabilities of a separation operation, a microchip used to implement a separation operation of an analysis sample without contamination or spillage is composed of a substrate and a cover, the substrate being provided with a trench-shaped channel in its upper surface and substrate reservoirs that are linked with this channel, and the cover hermetically sealing the upper surface of the channel, attachable to or detachable from the substrate, and provided with through-holes formed at positions corresponding to the substrate reservoirs, cover reservoirs that are formed on the inner sides of the through-holes for holding liquid that is introduced when the cover is in the state of hermetically sealing the upper surface of the channel, and partitions that are formed on the bottom surfaces of the cover reservoirs.

Abstract: A channel formed on a chip is opened without contaminating contents of the channel. Channels (107a) and (107b) provided on a substrate (103) are covered by pressing a lid (113) composed of a resin layer (102) and a plate-like lid (101) to a surface of the substrate (103). A fixing device has a retainer plate (104), which retains the plate-like lid (101) of a chip (112), a board (108) on which the substrate (103) is placed, and a screw (106). When covering the channels (107a) and (107b), the screw (106) is fastened and the lid (113) is pressed to the substrate (103) to be fixed. And, when opening an upper portion of the channels (107a) and (107b), the screw (106) is turned upward and a pressure is released, and the lid (113) is removed from the upper potion of the substrate (103).