Patents by Inventor Maciek Antoniewicz

Maciek Antoniewicz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthetic methylotrophy to liquid fuels and chemicals
    Patent number: 10717964
    Abstract: A non-naturally occurring microbe capable of growing in a medium comprising methanol is provided. The methanol contributes to a significant percentage (e.g., at least 40%) of the carbon source for the non-naturally occurring microbe, which expresses heterologous methanol dehydrogenase (MDH) and heterologous ribulose monophosphate (RuMP) pathway enzymes. Methods for producing liquid fuels and chemicals by the non-naturally occurring microbe and methods for preparing the non-naturally occurring microbe are also provided.
    Type: Grant
    Filed: July 23, 2018
    Date of Patent: July 21, 2020
    Assignee: University of Delaware
    Inventors: Eleftherios T. Papoutsakis, Sergios Nicolaou, Alan Fast, Vasiliki Falara, Robert Kyle Bennett, William Brian Whitaker, Nicholas Richard Sandoval, Jacqueline Gonzalez, Maciek Antoniewicz
  • SYNTHETIC METHYLOTROPHS AND USES THEREOF
    Publication number: 20200017888
    Abstract: The present invention provides a method for increasing production of a metabolite by a non-naturally occurring methylotroph, comprising growing the non-naturally occurring methylotroph in a medium comprising methanol. Expression of one or more native genes in the non-naturally occurring methylotroph is changed. Also provided are the non-naturally occurring methylotroph and preparation thereof.
    Type: Application
    Filed: February 13, 2018
    Publication date: January 16, 2020
    Applicant: University of Delaware
    Inventors: Eleftherios T. Papoutsaki, Robert Kyle Bennett, Jacqueline Gonzalez, William Brian Whitaker, Maciek Antoniewicz
  • SYNTHETIC METHYLOTROPHY TO LIQUID FUELS AND CHEMICALS
    Publication number: 20190048310
    Abstract: A non-naturally occurring microbe capable of growing in a medium comprising methanol is provided. The methanol contributes to a significant percentage (e.g., at least 40%) of the carbon source for the non-naturally occurring microbe, which expresses heterologous methanol dehydrogenase (MDH) and heterologous ribulose monophosphate (RuMP) pathway enzymes. Methods for producing liquid fuels and chemicals by the non-naturally occurring microbe and methods for preparing the non-naturally occurring microbe are also provided.
    Type: Application
    Filed: July 23, 2018
    Publication date: February 14, 2019
    Applicant: University of Delaware
    Inventors: Eleftherios T. Papoutsakis, Sergios Nicolaou, Alan Fast, Vasiliki Falara, Robert Kyle Bennett, William Brian Whitaker, Nicholas Richard Sandoval, Jacqueline Gonzalez, Maciek Antoniewicz
  • Synthetic methylotrophy to liquid fuels and chemicals
    Patent number: 10059920
    Abstract: A non-naturally occurring microbe capable of growing in a medium comprising methanol is provided. The methanol contributes to a significant percentage (e.g., at least 40%) of the carbon source for the non-naturally occurring microbe, which expresses heterologous methanol dehydrogenase (MDH) and heterologous ribulose monophosphate (RuMP) pathway enzymes. Methods for producing liquid fuels and chemicals by the non-naturally occurring microbe and methods for preparing the non-naturally occurring microbe are also provided.
    Type: Grant
    Filed: January 9, 2015
    Date of Patent: August 28, 2018
    Assignee: University of Delaware
    Inventors: Eleftherios T. Papoutsakis, Sergios Nicolaou, Alan Fast, Vasiliki Falara, Robert Kyle Bennett, William Brian Whitaker, Nicholas Richard Sandoval, Jacqueline Gonzalez, Maciek Antoniewicz
  • SYNTHETIC METHYLOTROPHY TO LIQUID FUELS AND CHEMICALS
    Publication number: 20160333308
    Abstract: A non-naturally occurring microbe capable of growing in a medium comprising methanol is provided. The methanol contributes to a significant percentage (e.g., at least 40%) of the carbon source for the non-naturally occurring microbe, which expresses heterologous methanol dehydrogenase (MDH) and heterologous ribulose monophosphate (RuMP) pathway enzymes. Methods for producing liquid fuels and chemicals by the non-naturally occurring microbe and methods for preparing the non-naturally occurring microbe are also provided.
    Type: Application
    Filed: January 9, 2015
    Publication date: November 17, 2016
    Applicant: University of Delaware
    Inventors: Eleftherios T. Papoutsakis, Sergios Nicolaou, Alan Fast, Vasiliki Falara, Robert Kyle Bennett, William Brian Whitaker, Nicholas Richard Sandoval, Jacqueline Gonzalez, Maciek Antoniewicz