Patents by Inventor Madalee M. Gassaway

Madalee M. Gassaway has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Class of mu-opioid receptor agonists
    Patent number: 10183919
    Abstract: The present invention provides a compound having the structure: or a pharmaceutically acceptable salt or ester thereof.
    Type: Grant
    Filed: March 12, 2015
    Date of Patent: January 22, 2019
    Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Andrew C. Kruegel, Adam Henke, Madalee M. Gassaway, Marie-Laure Rives, Jonathan A. Javitch, Dalibor Sames
  • OPIOID RECEPTOR MODULATORS
    Publication number: 20170334923
    Abstract: The present invention provides a compound having the structure wherein A is a ring structure, with or without substitution; X1 is C or N; X2 is N, O, or S; Y1 is H, -(alkyi), -(alkenyl), -(alkynyl), -(cycloalkyi), (haloalkyi), -(alkyl)-O-(alkyl) or -(alkyl)-(cycloalkyl); Y 2 is H, -(alkyi), -(alkenyl), -(alkynyl), -(cycloalkyi), (haloalkyi), -(alkyl)-O-(alkyl) or -(alkyl)-(cycloalkyl); Y3 is H-(alkyi), -(alkenyl), -(alkynyl), -(cycloalkyi), (haloalkyi), -(alkyl)-O-(alkyl) or -(alkyl)-(cycloalkyl); Y 4 is H-(alkyi), -(alkenyl), -(alkynyl), -(cycloalkyi), (haloalkyi), -(alkyl)-O-(alkyl) or -(alkyl)-(cycloalkyl); Y5 is H, -(alkyi), -(alkenyl), -(alkynyl), -(cycloalkyi), (haloalkyi), -(alkyl)-O-(alkyl) or -(alkyl)-(cycloalkyl); a and P are each present or absent and when present each is a bond.
    Type: Application
    Filed: November 25, 2015
    Publication date: November 23, 2017
    Applicant: The Trustees of Columbia University in the City of New York
    Inventors: Andrew C. KRUEGEL, Madalee M. GASSAWAY, Jonathan A. JAVITCH, Dalibor SAMES
  • A NEW CLASS OF MU-OPIOID RECEPTOR AGONISTS
    Publication number: 20170217913
    Abstract: The present invention provides a compound having the structure: or a pharmaceutically acceptable salt or ester thereof.
    Type: Application
    Filed: March 12, 2015
    Publication date: August 3, 2017
    Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
    Inventors: Andrew C. Kruegel, Adam Henke, Madalee M. Gassaway, Marie-Laure Rives, Jonathan A. Javitch, Dalibor Sames