Patents by Inventor Madan Katragadda

Madan Katragadda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CYSTEINE ENGINEERED ANTIBODY DRUG CONJUGATES
    Publication number: 20190099499
    Abstract: The invention relates to polypeptides, antibodies, and antigen-binding fragments thereof, that comprise an engineered cysteine for site-specific conjugation.
    Type: Application
    Filed: September 24, 2018
    Publication date: April 4, 2019
    Inventors: Madan Katragadda, Russell Dushin, Lawrence Nathan Tumey
  • Potent Compstatin Analogs
    Publication number: 20190016758
    Abstract: Compounds comprising peptides and peptidomimetics capable of binding C3 protein and inhibiting complement activation are disclosed. These compounds display greatly improved complement activation-inhibitory activity as compared with currently available compounds. Methods of making and using the compounds are also disclosed.
    Type: Application
    Filed: January 25, 2018
    Publication date: January 17, 2019
    Applicant: The Trustees of the University of Pennsylvania
    Inventors: John D. Lambris, Madan Katragadda
  • POTENT COMPSTATIN ANALOGS
    Publication number: 20170305971
    Abstract: Compounds comprising peptides and peptidomimetics capable of binding C3 protein and inhibiting complement activation are disclosed. These compounds display greatly improved complement activation-inhibitory activity as compared with currently available compounds. Methods of making and using the compounds are also disclosed.
    Type: Application
    Filed: April 18, 2017
    Publication date: October 26, 2017
    Applicant: The Trustees of the University of Pennsylvania
    Inventors: John D. Lambris, Madan Katragadda
  • POTENT COMPSTATIN ANALOGS
    Publication number: 20160096866
    Abstract: Compounds comprising peptides and peptidomimetics capable of binding C3 protein and inhibiting complement activation are disclosed. These compounds display greatly improved complement activation-inhibitory activity as compared with currently available compounds. Methods of making and using the compounds are also disclosed.
    Type: Application
    Filed: September 10, 2015
    Publication date: April 7, 2016
    Applicant: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: John D. LAMBRIS, Madan Katragadda
  • Potent compstatin analogs
    Patent number: 9169307
    Abstract: Compounds comprising peptides and peptidomimetics capable of binding C3 protein and inhibiting complement activation are disclosed. These compounds display greatly improved complement activation-inhibitory activity as compared with currently available compounds.
    Type: Grant
    Filed: January 14, 2011
    Date of Patent: October 27, 2015
    Assignee: The Trustees of the University of Pennsylvania
    Inventors: John D. Lambris, Madan Katragadda
  • RAGE Fusion Protein Compositions And Methods Of Use
    Publication number: 20130142792
    Abstract: Disclosed are fusion proteins comprising a RAGE polypeptide, wherein the RAGE polypeptide comprises a fragment of a mammalian wild type RAGE peptide and at least one point mutation in the RAGE polypeptide portion of the fusion protein relative to the wild type RAGE peptide. The point mutation may remove and/or alter a glycosylation site or an enzyme cleavage site. Also disclosed are nucleic acids encoding such proteins as well as methods of using such proteins for treating RAGE-mediated pathologies.
    Type: Application
    Filed: October 19, 2010
    Publication date: June 6, 2013
    Inventors: Jeffrey C. Webster, Gregory T. Bleck, Madan Katragadda, Manoj Rajadhyaksha, Bernard N. Violand, Jo-Ann Wentland, Linda Marie Rothlein
  • Potent Compstatin Analogs
    Publication number: 20120004393
    Abstract: Compounds comprising peptides and peptidomimetics capable of binding C3 protein and inhibiting complement activation are disclosed. These compounds display greatly improved complement activation-inhibitory activity as compared with currently available compounds.
    Type: Application
    Filed: January 14, 2011
    Publication date: January 5, 2012
    Inventors: John D. LAMBRIS, Madan Katragadda
  • Potent compstatin analogs
    Patent number: 7888323
    Abstract: Compounds comprising peptides and peptidomimetics capable of binding C3 protein and inhibiting complement activation are disclosed. These compounds display greatly improved complement activation-inhibitory activity as compared with currently available compounds.
    Type: Grant
    Filed: November 28, 2006
    Date of Patent: February 15, 2011
    Assignee: The Trustees Of The University Of Pennsylvania
    Inventors: John D. Lambris, Madan Katragadda
  • Potent compstatin analogs
    Publication number: 20080227717
    Abstract: Compounds comprising peptides and peptidomimetics capable of binding C3 protein and inhibiting complement activation are disclosed. These compounds display greatly improved complement activation-inhibitory activity as compared with currently available compounds.
    Type: Application
    Filed: November 28, 2006
    Publication date: September 18, 2008
    Inventors: John D. Lambris, Madan Katragadda