Patents by Inventor Madana M.R. Ambavaram

Madana M.R. Ambavaram has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11746356
    Abstract: Methods comprising DNA constructs and polynucleotides of functional transcription factors for improving photosynthetic capacity, biomass and/or grain yield and stress tolerance in various crop and model plants, dicots and monocots with the C3 or C4 photosynthetic pathways are described herein.
    Type: Grant
    Filed: March 24, 2021
    Date of Patent: September 5, 2023
    Assignee: YIELD10 BIOSCIENCE, INC.
    Inventors: Madana M. R. Ambavaram, Mariya Somleva
  • Publication number: 20220235364
    Abstract: A modified plant is provided. The modified plant includes a polynucleotide including a promoter operably linked to a coding sequence. The coding sequence encodes a transcription factor that has at least 30% sequence identity to one or more of SEQ ID NOs: 27, 204, 10, 19, 1-9, 11-18, 20-26, 28-203, 205, 237, or 242-310. The promoter is non-cognate with respect to the coding sequence. Also provided is a method for producing a modified plant having increased seed yield and/or oil content in comparison to a reference plant by transformation. Also provided is a method for producing a modified plant having increased seed yield and/or oil content in comparison to a reference plant by editing.
    Type: Application
    Filed: May 13, 2020
    Publication date: July 28, 2022
    Inventors: Madana M.R. AMBAVARAM, Venkatesh BOLLINA, Frank Anthony SKRALY, Meghna MALIK, Kristi D. SNELL
  • Publication number: 20210348182
    Abstract: A genetically engineered land plant that expresses a protein that has homology to a plant invertase inhibitor and/or a pectin methylesterase inhibitor and that increases seed yield with increased expression (“an ISY protein”) is disclosed. The plant comprises a modified gene for the ISY protein. The ISY protein comprises one or more of an ISY protein of Camelina sativa comprising SEQ ID NO: 2 or a fragment, Camelina sativa homolog, or ortholog thereof. The modified gene comprises a promoter and a nucleic acid sequence encoding the ISY protein. The promoter is non-cognate with respect to the nucleic acid sequence encoding the ISY protein. The modified gene is configured such that transcription of the nucleic acid sequence is initiated from the promoter and results in expression of the ISY protein. A genetically engineered land plant that expresses an RNA that increases seed yield with increased expression also is disclosed.
    Type: Application
    Filed: September 3, 2019
    Publication date: November 11, 2021
    Inventors: Jihong TANG, Meghna MALIK, Nirmala SHARMA, Claire BURKITT, Yuanyuan JI, Madana M.R. AMBAVARAM, Kieran RYAN, Oliver P. PEOPLES, Kristi D. SNELL, Frank Anthony SKRALY, Venkatesh BOLLINA
  • Publication number: 20210332376
    Abstract: Methods comprising DNA constructs and polynucleotides of functional transcription factors for improving photosynthetic capacity, biomass and/or grain yield and stress tolerance in various crop and model plants, dicots and monocots with the C3 or C4 photosynthetic pathways are described herein.
    Type: Application
    Filed: March 24, 2021
    Publication date: October 28, 2021
    Inventors: Madana M.R. Ambavaram, Mariya Somleva
  • Patent number: 11072798
    Abstract: Methods comprising DNA constructs and polynucleotides of functional transcription factors for improving photosynthetic capacity, biomass and/or grain yield and stress tolerance in various crop and model plants, dicots and monocots with the C3 or C4 photosynthetic pathways are described herein.
    Type: Grant
    Filed: September 13, 2019
    Date of Patent: July 27, 2021
    Assignee: YIELD 10 BIOSCIENCE, INC.
    Inventors: Madana M. R. Ambavaram, Mariya Somleva
  • Publication number: 20210139924
    Abstract: The present invention identifies a number of transcription factors of corn, genes encoding the transcription factors, and methods to enhance characteristics of corn such as higher photosynthesis rates, higher photosynthetic electron transport rates, reduced photorespiration rates, higher biomass yield or content, higher seed yield, improved harvest index, higher oil content, improved nutritional composition, improved nitrogen use efficiency, drought resistance, flood resistance, disease resistance, salt tolerance, higher C02 assimilation rate, and lower transpiration rate in a plant by upregulating the genes encoding the transcription factors. Compositions of the invention comprise polypeptide sequences, polynucleotide sequences, variants, orthologs, and fragments thereof. Methods comprise introducing into corn plants systems that increase the expression or activity of transcription factors of the invention. Methods and compositions also provide corn plants with enhanced performance.
    Type: Application
    Filed: April 1, 2019
    Publication date: May 13, 2021
    Inventors: Madana M.R. AMBAVARAM, Jihong TANG, Kristi D. SNELL, Oliver P. PEOPLES
  • Publication number: 20200347394
    Abstract: Plant transcription factors and genes encoding the transcription factors are disclosed. Methods to enhance characteristics in a plant by downregulating the genes encoding the transcription factors also are disclosed. The enhanced characteristics can include higher photosynthesis rates, reduced photorespiration rates, higher biomass yield or content, higher seed yield, improved harvest index, higher oil content, improved nutritional composition, improved nitrogen use efficiency, drought resistance, flood resistance, disease resistance, faster seed germination and plant emergence, improved seedling vigor, salt tolerance, higher CO2 assimilation rate, and lower transpiration rate. Modified plants in which the genes encoding the transcription factors are downregulated also are disclosed. Compositions of the invention comprise polynucleotide sequences, polypeptide sequences, variants, orthologs, and fragments thereof.
    Type: Application
    Filed: November 2, 2018
    Publication date: November 5, 2020
    Inventors: Madana M.R. AMBAVARAM, Jihong TANG, Mariya SOMLEVA, Kieran RYAN, Oliver P. PEOPLES, Kristi D. SNELL
  • Publication number: 20200055908
    Abstract: A transgenic land plant is provided. The transgenic land plant comprises a mitochondrial transporter protein of a eukaryotic algae. The mitochondrial transporter protein of the eukaryotic algae is heterologous with respect to the transgenic land plant. The mitochondrial transporter protein is a sequence or ortholog of CCP1 of Chlamydomonasreinhardtii, a mitochondrial transporter protein of Chlorella sorokiniana, a mitochondrial transporter protein of Chlorella variabilis, a mitochondrial transporter protein of Chondrus crispus, a mitochondrial transporter protein of Gonium pectorale, or a mitochondrial transporter protein of Volvox carteri. The mitochondrial transporter protein is localized to mitochondria of the transgenic land plant based on a mitochondrial targeting signal intrinsic to the mitochondrial transporter protein.
    Type: Application
    Filed: February 22, 2018
    Publication date: February 20, 2020
    Inventors: Oliver P. Peoples, Kristi D. Snell, Meghna Malik, Madana M.R. Ambavaram
  • Publication number: 20200048651
    Abstract: Methods comprising DNA constructs and polynucleotides of functional transcription factors for improving photosynthetic capacity, biomass and/or grain yield and stress tolerance in various crop and model plants, dicots and monocots with the C3 or C4 photosynthetic pathways are described herein.
    Type: Application
    Filed: September 13, 2019
    Publication date: February 13, 2020
    Inventors: Madana M.R. Ambavaram, Mariya Somleva
  • Patent number: 10450580
    Abstract: Methods comprising DNA constructs and polynucleotides of functional transcription factors for improving photosynthetic capacity, biomass and/or grain yield and stress tolerance in various crop and model plants, dicots and monocots with the C3 or C4 photosynthetic pathways are described herein.
    Type: Grant
    Filed: February 15, 2018
    Date of Patent: October 22, 2019
    Assignee: Yield10 Bioscience, Inc.
    Inventors: Madana M.R. Ambavaram, Mariya Somleva
  • Publication number: 20160194650
    Abstract: Methods comprising DNA constructs and polynucleotides of functional transcription factors for improving photosynthetic capacity, biomass and/or grain yield and stress tolerance in various crop and model plants, dicots and monocots with the C3 or C4 photosynthetic pathways are described herein.
    Type: Application
    Filed: December 18, 2013
    Publication date: July 7, 2016
    Inventors: Madana M.R. Ambavaram, Mariya Somleva