Patents by Inventor Madduri Srinivasarao

Madduri Srinivasarao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FIBROBLAST ACTIVATION PROTEIN-TARGETED MAGNETIC RESONANCE IMAGING AGENTS, COMPOSITIONS, AND METHODS OF USE
    Publication number: 20230405153
    Abstract: A conjugate comprising FL-L-IA, wherein FL is a radical of a small molecule ligand that specifically binds with fibroblast activation protein (FAP), L is a linker, which binds an FL to IA, and IA is a radical of a magnetic resonance imaging (MRI) agent, or a pharmaceutically acceptable salt thereof; a composition comprising same; and a method of using the conjugate or composition to image cells, a tissue, or an organ that express(es) FAP with magnetic resonance imaging.
    Type: Application
    Filed: June 16, 2023
    Publication date: December 21, 2023
    Inventors: Philip Stewart Low, Ramesh Mukkamala, Madduri Srinivasarao
  • PI3 KINASE INHIBITORS AND USES THEREOF
    Publication number: 20230158153
    Abstract: A compound of the formula (II); a pharmaceutical composition comprising same; and methods for treating a fibrotic disease in a subject.
    Type: Application
    Filed: April 9, 2021
    Publication date: May 25, 2023
    Inventors: Philip Stewart Low, Madduri Srinivasarao
  • FIBROBLAST ACTIVATION PROTEIN (FAP)-TARGETED IMAGING AND THERAPY OF CANCERS AND OTHER FIBROTIC AND INFLAMMATORY DISEASES
    Publication number: 20220409747
    Abstract: Fibroblast activation protein (FAP)-targeting compounds (e.g., conjugates); a method for imaging cancer or fibrosis; and methods for treating an inflammatory disease/disorder and cancer.
    Type: Application
    Filed: September 17, 2020
    Publication date: December 29, 2022
    Inventors: Philip Stewart Low, Madduri Srinivasarao, Ramesh Mukkamala
  • DESIGN AND EFFICIENT SYNTHESIS OF LIPID-FLUORESCEIN CONJUGATES FOR CAR-T CELL THERAPY
    Publication number: 20220280648
    Abstract: The disclosure relates to lipid-fluorescein conjugates, compositions comprising same, and methods of synthesis and use, such as in the treatment of cancer.
    Type: Application
    Filed: July 2, 2020
    Publication date: September 8, 2022
    Inventors: Philip Stewart Low, Madduri Srinivasarao
  • MULTIVALENT FIBROBLAST-TARGETED AGENTS AND METHODS OF USE
    Publication number: 20220265870
    Abstract: Multivalent ligand-targeted active agents, such as detectable agents or therapeutic agents, for the imaging and treatment, respectively, of fibroblast activation protein (FAP)-positive cancer-associated fibroblasts (CAFs) and activated myofibroblasts in cancers and other fibrotic diseases.
    Type: Application
    Filed: July 22, 2020
    Publication date: August 25, 2022
    Inventors: Philip Stewart Low et al., Madduri Srinivasarao, Ramesh Mukkamala
  • Fertilizer composition and methods of making and using same
    Patent number: 11104618
    Abstract: In accordance with the present invention, disclosed herein is a fertilizer core and fertilizer granule and methods related thereto. The fertilizer core particle has an outer surface and comprising one or more fertilizer additives, one or more binders, and one or more pH buffering agents, and wherein the fertilizer core particle comprises from about 10 wt % to about 99 wt % of the one or more binders.
    Type: Grant
    Filed: July 18, 2016
    Date of Patent: August 31, 2021
    Assignee: SABIC GLOBAL TECHNOLOGIES B.V.
    Inventors: Sabeshan Kanagalingam, Ravi Hegde, Madduri Srinivasarao, Rajamalleswaramma Koripelly, Samik Gupta, Nilkamal Bag, Satish Burla, Yoganand Gurumallappa
  • Fertilizer composition and methods of making and using same
    Patent number: 11066342
    Abstract: In accordance with the present invention, disclosed herein is a fertilizer core and fertilizer granule and methods related thereto. The fertilizer core particle has an outer surface and comprising one or more fertilizer additives, one or more binders, and one or more pH buffering agents, and wherein the fertilizer core particle comprises from about 10 wt % to about 99 wt % of the one or more binders.
    Type: Grant
    Filed: July 18, 2016
    Date of Patent: July 20, 2021
    Assignee: SABIC GLOBAL TECHNOLOGIES B.V.
    Inventors: Sabeshan Kanagalingam, Ravi Hegde, Madduri Srinivasarao, Rajamalleswaramma Koripelly, Samik Gupta, Nilkamal Bag, Satish Burla, Yoganand Gurumallappa
  • FERTILIZER CAPSULE COMPRISING ONE OR MORE CORES AND METHOD OF MAKING SAME
    Publication number: 20200207678
    Abstract: In accordance with the present invention, disclosed herein is a fertilizer capsule comprising one or more cores, wherein each of the one or more cores independently comprises one or more fertilizer additives and a binder, and wherein each of the one or more cores comprises from 10 wt % to 99 wt % of the binder Also in accordance with the present invention, disclosed here is a method of producing a fertilizer core via an extrusion process.
    Type: Application
    Filed: March 9, 2020
    Publication date: July 2, 2020
    Applicant: SAUDI BASIC INDUSTRIES CORPORATION
    Inventors: Sabeshan KANAGALINGAM, Ravi HEGDE, Madduri SRINIVASARAO, Anton KUMANAN, Rajamalleswaramma KORIPELLY, Samik GUPTA
  • Fertilizer composition and methods of making and using same
    Patent number: 10689306
    Abstract: In accordance with the present invention, disclosed herein is a fertilizer core particle and fertilizer granule. The fertilizer core particle has one or more fertilizer additives, one or more binders comprising a wax, and one or more pH buffering agents, and wherein the core particle comprises from about 10 wt % to about 99 wt % of the one or more binders comprising a wax.
    Type: Grant
    Filed: July 18, 2016
    Date of Patent: June 23, 2020
    Assignee: SABIC GLOBAL TECHNOLOGIES B.V.
    Inventors: Sabeshan Kanagalingam, Ravi Hegde, Madduri Srinivasarao, Rajamalleswaramma Koripelly, Samik Gupta, Nilkamal Bag, Satish Burla, Yoganand Gurumallappa
  • Fertilizer capsule comprising one or more cores and method of making same
    Patent number: 10640430
    Abstract: Fertilizer capsules, methods of making the fertilizer capsules, and uses of the fertilizer capsules are described. A fertilizer capsule can include one or more cores. Each core can include one or more fertilizer additives and 10 to 99 wt. % of an extrudable binder.
    Type: Grant
    Filed: January 28, 2015
    Date of Patent: May 5, 2020
    Assignee: SAUDI BASIC INDUSTRIES CORPORATION
    Inventors: Sabeshan Kanagalingam, Ravi Hegde, Madduri Srinivasarao, Anton Kumanan, Rajamalleswaramma Koripelly, Samik Gupta
  • Targeted Ligand-Payload Based Drug Delivery for Cell Therapy
    Publication number: 20200054676
    Abstract: A drug delivery platform providing flexible fine tune of cell therapy is disclosed herein. Particularly, an engineered fusion protein is coupled with a high affinity ligand carrying at least one payload of drug to be internalized by the transplanted cell to observe or regulate transplanted cell therapy effects.
    Type: Application
    Filed: February 17, 2018
    Publication date: February 20, 2020
    Inventors: Philip S. LOW, Madduri SRINIVASARAO, Boning ZHANG
  • FERTILIZER COMPOSITION AND METHODS OF MAKING AND USING SAME
    Publication number: 20180208519
    Abstract: In accordance with the present invention, disclosed herein is a fertilizer core and fertilizer granule and methods related thereto. The fertilizer core particle has an outer surface and comprising one or more fertilizer additives, one or more binders, and one or more pH buffering agents, and wherein the fertilizer core particle comprises from about 10 wt % to about 99 wt % of the one or more binders.
    Type: Application
    Filed: July 18, 2016
    Publication date: July 26, 2018
    Inventors: Sabeshan KANAGALINGAM, Ravi HEGDE, Madduri SRINIVASARAO, Rajamalleswaramma KORIPELLY, Samik GUPTA, Nilkamal BAG, Satish BURLA, Yoganand GURUMALLAPPA
  • FERTILIZER COMPOSITION AND METHODS OF MAKING AND USING SAME
    Publication number: 20180208513
    Abstract: In accordance with the present invention, disclosed herein is a fertilizer core particle and fertilizer granule. The fertilizer core particle has one or more fertilizer additives, one or more binders comprising a wax, and one or more pH buffering agents, and wherein the core particle comprises from about 10 wt % to about 99 wt % of the one or more binders comprising a wax.
    Type: Application
    Filed: July 18, 2016
    Publication date: July 26, 2018
    Inventors: Sabeshan KANAGALINGAM, Ravi HEGDE, Madduri SRINIVASARAO, Rajamalleswaramma KORIPELLY, Samik GUPTA, Nilkamal BAG, Satish BURLA, Yoganand GURUMALLAPPA
  • FERTILIZER CAPSULE COMPRISING ONE OR MORE CORES AND METHOD OF MAKING SAME
    Publication number: 20160340265
    Abstract: In accordance with the present invention, disclosed herein is a fertilizer capsule comprising one or more cores, wherein each of the one or more cores independently comprises one or more fertilizer additives and a binder, and wherein each of the one or more cores comprises from 10 wt % to 99 wt % of the binder Also in accordance with the present invention, disclosed here is a method of producing a fertilizer core via an extrusion process.
    Type: Application
    Filed: January 28, 2015
    Publication date: November 24, 2016
    Inventors: Sabeshan Kanagalingam, Ravi Hegde, Madduri Srinivasarao, Anton Kumanan, Rajamalleswaramma Koripelly, Samik Gupta