Patents by Inventor Madelaine Robertson

Madelaine Robertson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR MODULATING PLASMINOGEN
    Publication number: 20240141357
    Abstract: The present disclosure provides a duplex or single-stranded siRNA molecule against plasminogen, the siRNA molecule containing modified or unmodified nucleotides and wherein at least one strand of the duplex or the single-stranded siRNA has a sequence that has at least 80% sequence identity to any one of SEQ NOs: 1 to 28. Further provided is a duplex or single-stranded siRNA molecule against plasminogen, the siRNA molecule containing modified or unmodified nucleotides and is between 25 and 35 nucleotides in length. The siRNA molecule may be formulated in a lipid nanoparticle as described herein.
    Type: Application
    Filed: February 14, 2022
    Publication date: May 2, 2024
    Applicant: THE UNIVERSITY OF BRITISH COLUMBIA
    Inventors: Christian J. Kastrup, Amy W. Strilchuk, Jerry Leung, Pieter R. Cullis, Madelaine Robertson