Patents by Inventor Madeleine Bouzon

Madeleine Bouzon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mutants of Deoxycytidine Kinase Having Extended Enzymatic Activity
    Publication number: 20100136693
    Abstract: The invention relates to a method for artificial in vivo evolution of proteins, said method making it possible to bring about the evolution of a protein X by complementation of a relative protein Y, X and Y both belonging to the same class of enzyme commission (EC) nomenclature or belonging to related classes. The mutants D133E and R104Q of desoxycytidine kinase (DCK) were obtained; both of said mutations result in acquisition of thymidine kinase activity by DCK.
    Type: Application
    Filed: May 8, 2009
    Publication date: June 3, 2010
    Inventors: Philippe Marliere, Sylvie Pochet, Madeleine Bouzon
  • Mutants of deoxycytidine kinase having extended enzymatic activity
    Patent number: 7547513
    Abstract: The invention relates to a method for artificial in vivo evolution of proteins, said method making it possible to bring about the evolution of a protein X by complementation of a relative protein Y, X and Y both belonging to the same class of enzyme commission (EC) nomenclature or belonging to related classes. The mutants D133E and R104Q of desoxycytidine kinase (DCK) were obtained; both of said mutations result in acquisition of thymidine kinase activity by DCK.
    Type: Grant
    Filed: May 19, 2005
    Date of Patent: June 16, 2009
    Assignees: Institut Pasteur, Centre National de la Recherche Scientifique (CNRS)
    Inventors: Philippe Marliere, Sylvie Pochet, Madeleine Bouzon
  • Mutants of desoxycytidine kinase having extended enzymatic activity
    Publication number: 20070037269
    Abstract: The invention relates to a method for artificial in vivo evolution of proteins, said method making it possible to bring about the evolution of a protein X by complementation of a relative protein Y,X and Y both belonging to the same class of enzyme commission (EC) nomenclature or belonging to related classes. The mutants D133E and R104Q of desoxycytidine kinase (DCK) were obtained; both of said mutations result in acquisition of thymidine kinase activity by DCK.
    Type: Application
    Filed: May 19, 2005
    Publication date: February 15, 2007
    Inventors: Philippe Marliere, Sylvie Pochet, Madeleine Bouzon