Patents by Inventor Madeleine Mosse

Madeleine Mosse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5089251
    Abstract: The present invention relates to aromatic derivatives of the formula: ##STR1## in which: n represents an integer between 2 and 10;R.sub.1 and R.sub.2 are identical or different and represent a cycloalkyl containing 3 to 6 carbon atoms or an alkyl containing from 1 to 6 carbon atoms which is unsubstituted or substituted by a phenyl or benzyl group; orR.sub.1 and R.sub.2, together with the nitrogen atom to which they are bonded, form a heterocycle selected from pyrrolidin-1-yl, piperidino, azepin-1-yl, hexamethyleneimino, 4-methylpiperidino, 4-benzylpiperidino, 4-phenylpiperidino, 1,2,3,4-tetrahydroisoquinol-2-yl, morpholino and imidazol-1-yl groups;R.sub.3 represents a hydrogen, a halogen, a methyl or a phenyl;R.sub.4 represents a hydrogen, a halogen or a methyl; or R.sub.3 and R.sub.4, taken together with the benzene ring to which they are bonded, form a naphth-1-yl or naphth-2-yl group;Y represents a direct bond, a methyleneoxy group, a methylenethio group or a vinylene group; andR.sub.
    Type: Grant
    Filed: January 24, 1990
    Date of Patent: February 18, 1992
    Assignee: Sanofi
    Inventors: Madeleine Mosse, Vincenzo Proietto
  • Patent number: 5036077
    Abstract: The invention relates to compounds of the formula: ##STR1## in which: Ar represents a phenyl group substituted by R.sub.2, R.sub.3 and R.sub.4, or a naphth-1-yl or naphth-2-yl group, unsubstituted or substituted by 1 or 2 halogen atoms;X represents an oxygen atom or a sulfur atom;R.sub.1 represents H or a halogen atom;R.sub.2 represents a halogen atom, a trifluoromethyl group, a phenyl group which is unsubstituted by 1 or 3 halogen atoms, a benzyl group which is unsubstituted or substituted by 1 to 3 halogen atoms, a phenoxy group which is unsubstituted or substituted by 1 to 3 halogen atoms, or a C.sub.1 -C.sub.4 alkyl group;R.sub.3 and R.sub.4 represents H, a halogen atom or a C.sub.1 -C.sub.4 alkyl group; andthe benzyl group substitutes the piperidino radical in the 2-, 3- or 4-position,and their salts with mineral or organic acids.
    Type: Grant
    Filed: September 15, 1988
    Date of Patent: July 30, 1991
    Assignee: Sanofi
    Inventors: Didier Van Broeck, Madeleine Mosse
  • Patent number: 4946868
    Abstract: The invention concerns compositions with antimicrobial activity.These compositions contain a benzoic acid derivative with the formula: ##STR1## in which: A represents a straight or branched alkyl chain with 3 to 4 carbon atoms,X represents the oxygen atom or a direct bond,R represents hydrogen or an alkyl group with 2 to 6 carbon atoms, possibly substituted by an alcohol function and a salt of such a derivative.Applications: drugs, disinfectants and preservative agents.
    Type: Grant
    Filed: August 13, 1984
    Date of Patent: August 7, 1990
    Assignee: Sanofi
    Inventors: Henri Demarne, Robert Filhol, Madeleine Mosse
  • Patent number: 4916156
    Abstract: The present invention relates to aromatic derivatives of the formula: ##STR1## in which: n represents an integer between 2 and 10;R.sub.1 and R.sub.2 are identical or different and represent a cycloalkyl containing 3 to 6 carbon atoms or an alkyl containing from 1 to 6 carbon atoms which is unsubstituted or substituted by a phenyl or benzyl group; orR.sub.1 and R.sub.2, together with the nitrogen atom to which they are bonded, form a heterocycle selected from pyrrolidin-1-yl, piperidino, azepin-1-yl, hexamethyleneimino, 4-methylpiperidino, 4-benzylpiperidino, 4-phenylpiperidino, 1,2,3,4-tetrahydroisoquinol-2-yl, morpholino and imidazol-1-yl groups;R.sub.3 represents a hydrogen, a halogen, a methyl or a phenyl;R.sub.4 represents a hydrogen, a halogen or a methyl; or R.sub.3 and R.sub.4, taken together with the benzene ring to which they are bonded, form a naphth-1-yl or naphth-2-yl group;Y represents a direct bond, a methyleneoxy group, a methylenethio group or a vinylene group; andR.sub.
    Type: Grant
    Filed: April 6, 1988
    Date of Patent: April 10, 1990
    Assignee: Sanofi
    Inventors: Madeleine Mosse, Vincenzo Proietto
  • Patent number: 4820717
    Abstract: The present invention relates to new aromatic derivatives of formula: ##STR1## wherein: Alk is an alkylene group with 1 to 10 carbon atoms,R.sub.1 is hydrogen or an alkyl with 1 to 6 carbon atoms,R.sub.2 and R.sub.3 are similar or different and represent a cycloalkyl with 3 to 6 carbon atoms or a striaght or branched alkyl with 1 to 6 carbon atoms, either substituted or non-substituted by a phenyl or methyl phenyl group, or R.sub.2 and R.sub.3 form, together with the atom of nitrogen to which they are bonded, a mono-nitrogenous heterocycle containing no other heteroatom, such as pyrrolidino, piperidino, azepino, hexamethylene-imino, 4-methyl-piperidino, 4-phenyl-piperidino, 1,2,3,4-tetrahydro-2-isoquinolyl, 4-benzyl-piperidino;R.sub.4 is hydrogen, halogen, methyl or phenyl,R.sub.5 is hydrogen, halogen or methyl,or R.sub.4 and R.sub.5 together with the benzene ring to which they are bonded, constitute a 1-naphthyl or 2-naphthyl group,and the pharmaceutically acceptable salts with mineral or organic acids.
    Type: Grant
    Filed: September 30, 1986
    Date of Patent: April 11, 1989
    Assignee: Sanofi
    Inventors: Madeleine Mosse, Henri Demarne, Vincenzo Proietto
  • Patent number: 4720581
    Abstract: The present invention relates to benzamidine derivatives corresponding to the general formula ##STR1## in which: A represents a linear or branched alkyl chain containing from 3 to 9 carbon atoms; andX represents the oxygen atom or a direct bond, with the restriction that if X represents a direct bond, the benzamidine and the alkanol group are located in the para position, and also the pharmaceutically acceptable salts of the products of the formula (I);it also relates to a process for the preparation of the products of the formula (I) and the drugs for external use which contain a product of the formula (I).
    Type: Grant
    Filed: July 17, 1984
    Date of Patent: January 19, 1988
    Assignee: Sanofi
    Inventors: Madeleine Mosse, Henri Demarne, Robert Filhoi
  • Patent number: 4691043
    Abstract: Benzoic acid derivatives with the general formula: ##STR1## in which: A represents a straight or branched alkyl chain with 5 to 10 carbon atoms,X represents the oxygen atom or a direct bond,R represents hydrogen or an alkyl group with 2 to 6 carbon atoms, possibly substituted by an alcohol function,and the salts of the said derivatives.These derivatives display antimicrobial activity and are suitable as antiseptics, disinfectants and preservatives, particularly in the fields of pharmaceuticals, cosmetology and agri-foodstuffs.
    Type: Grant
    Filed: January 7, 1986
    Date of Patent: September 1, 1987
    Assignee: Sanofi
    Inventors: Henri Demarne, Robert Filhol, Madeleine Mosse