Patents by Inventor Madeline A. LANCASTER

Madeline A. LANCASTER has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Supported in vitro developed tissue culture and culturing methods
    Patent number: 11884933
    Abstract: An elongated or fiber-supported multicellular aggregation of multipotent cells, wherein multipotent cells are arranged in an oblong or longish arrangement with an aspect ratio of a prolate dimension to a perpendicular dimension of at least 2:1, or supported by a fibrous structure, and wherein the aggregate contains cells at different stages of differentiation, and the aggregate contains polar cells; methods of generating such aggregates; methods of developing the aggregates further into tissue organoids and kits for such methods.
    Type: Grant
    Filed: January 11, 2017
    Date of Patent: January 30, 2024
    Assignee: IMBA—INSTITUT FÜR MOLEKULARE BIOTECHNOLOGIE GMBH
    Inventors: Jürgen Knoblich, Madeline A. Lancaster
  • THREE DIMENSIONAL HETEROGENEOUSLY DIFFERENTIATED TISSUE CULTURE
    Publication number: 20220333069
    Abstract: The present invention provides an artificial tissue culture comprising a heterogeneous population of cells of at least two different tissue sections, wherein said tissue sections are in a three dimensional structure, method of generating such a tissue and kits suitable for said method or maintain a three dimensional tissue culture.
    Type: Application
    Filed: May 2, 2022
    Publication date: October 20, 2022
    Inventors: Juergen Knoblich, Madeline A. Lancaster
  • Three dimensional heterogeneously differentiated tissue culture
    Patent number: 11345889
    Abstract: The present invention provides an artificial tissue culture comprising a heterogeneous population of cells of at least two different tissue sections, wherein said tissue sections are in a three dimensional structure, method of generating such a tissue and kits suitable for said method or maintain a three dimensional tissue culture.
    Type: Grant
    Filed: July 23, 2019
    Date of Patent: May 31, 2022
    Assignee: IMBA-Institut fur Molekulare Biotechnologie GMBH
    Inventors: Juergen Knoblich, Madeline A. Lancaster
  • CHOROID PLEXUS ORGANOIDS AND METHODS FOR PRODUCTION THEREOF
    Publication number: 20220106571
    Abstract: Methods and materials relating to cultured choroid plexus organoids comprising: (a) an epithelium comprising a tight epithelial barrier; and/or (b) one or more cysts surrounded by an epithelium, plus other authentic features and markers.
    Type: Application
    Filed: January 23, 2020
    Publication date: April 7, 2022
    Applicant: UNITED KINGDOM RESEARCH AND INNOVATION
    Inventors: MADELINE A. LANCASTER, LAURA PELLEGRINI
  • THREE DIMENSIONAL HETEROGENEOUSLY DIFFERENTIATED TISSUE CULTURE
    Publication number: 20190338245
    Abstract: The present invention provides an artificial tissue culture comprising a heterogeneous population of cells of at least two different tissue sections, wherein said tissue sections are in a three dimensional structure, method of generating such a tissue and kits suitable for said method or maintain a three dimensional tissue culture.
    Type: Application
    Filed: July 23, 2019
    Publication date: November 7, 2019
    Inventors: Juergen Knoblich, Madeline A. Lancaster
  • Three dimensional heterogeneously differentiated tissue culture
    Patent number: 10407664
    Abstract: The present invention provides an artificial tissue culture comprising a heterogeneous population of cells of at least two different tissue sections, wherein said tissue sections are in a three dimensional structure, method of generating such a tissue and kits suitable for said method or maintain a three dimensional tissue culture.
    Type: Grant
    Filed: December 13, 2013
    Date of Patent: September 10, 2019
    Assignee: IMBA—Institut Fur Molekulare Biotechnologie GMBH
    Inventors: Juergen Knoblich, Madeline A. Lancaster
  • SUPPORTED IN VITRO DEVELOPED TISSUE CULTURE AND CULTURING METHODS
    Publication number: 20190017016
    Abstract: An elongated or fiber-supported multicellular aggregation of multipotent cells, wherein multipotent cells are arranged in an oblong or longish arrangement with an aspect ratio of a prolate dimension to a perpendicular dimension of at least 2:1, or supported by a fibrous structure, and wherein the aggregate contains cells at different stages of differentiation, and the aggregate contains polar cells; methods of generating such aggregates; methods of developing the aggregates further into tissue organoids and kits for such methods.
    Type: Application
    Filed: January 11, 2017
    Publication date: January 17, 2019
    Inventors: Jürgen KNOBLICH, Madeline A. LANCASTER