Abstract: Disclosed herein are systems and methods for providing targeted temperature management (TTM) therapy to a patient. For example, TTM systems can include rotatable connector systems for coupling a fluid deliver line to a thermal contact pad. Embodiments of the connector system can include connector pairs that comprise one lumen or multiple lumens. The TTM system includes embodiments where a second thermal pad is coupled to a first thermal pad.

Abstract: A medical pad for exchanging thermal energy between a targeted temperature management (TTM) fluid and a patient. The medical pad includes a fluid containing layer configured for circulation of a TTM fluid therein. The pad may further include a bistable stiffening structure configured to transition between a first stable shape and a second stable shape. The pad may further include a thermally-conductive compressible foam layer disposed between the fluid containing layer and a patient contact side of the pad. a self-adhering stretchable band configured to secure the pad to the patient. The pad may further include a semi-permeable layer disposed between an underside of the fluid containing layer and a hydrogel layer so that the TTM fluid may migrate from the fluid containing layer to the hydrogel layer.

Abstract: Disclosed are systems, pads, and methods for targeted temperature management. A pad can include a multilayered pad body, a pad inlet connector, and a pad outlet connector. The pad body can include a plurality of separable longitudinal portions, wherein each longitudinal portion of the longitudinal portions includes a conduit, a patient-interfacing layer over the conduit, and an insulation layer over the conduit opposite the patient-interfacing layer. The conduit can be configured to convey a temperature-controlled fluid as a supply fluid from a hydraulic system or convey a return fluid back to the hydraulic system. The patient-interfacing layer can include a thermally conductive medium configured for placement on a patient’s body. The insulation layer can include an insulative foam. The pad inlet connector can be configured for charging the pad with the supply fluid while the pad outlet connector can be configured for discharging the return fluid from the pad.

Abstract: A sealing member for providing a seal between fluid connectors includes a tubular member defining a lumen extending between a first end and a second end. The tubular member may receive a first connector via the first end and a second connector via the second end, and includes an annular wall extending between a first annular portion adjacent the first end and a second annular portion adjacent the second end. The first annular portion may engage the first connector, and the second annular portion may engage the second connector. When a pressure within the lumen is negative, atmospheric acting inward on the annular wall compresses the sealing member to define a contact force between the second annular portion and the second connector sufficient to define a fluid seal between the sealing member and the second connector.

Abstract: Disclosed herein are systems, pads, and methods for targeted temperature management. For example, a pad can include a multilayered pad body, a pad inlet connector, and a pad outlet connector. The pad body can include a conduit layer and a non-adhesive, thermally conductive layer over the conduit layer. The conduit layer can include one or more conduits configured to convey a temperature-controlled fluid as a supply fluid from a hydraulic system of a control module. The one-or-more conduits can also configured to convey the temperature-controlled fluid as a return fluid back to the hydraulic system. The conductive layer can be configured for placement on a portion of a patient's body. The pad inlet connector can include a pad inlet configured for charging the conduit layer with the supply fluid. The pad outlet connector can include a pad outlet configured for discharging the return fluid from the conduit layer.

Abstract: Disclosed herein are systems, pads, and methods thereof for targeted temperature management. In an example, a pad for targeted temperature management can include a pad body, a conduit system, one or more inlets, and one or more outlets. The pad body can be of a conformable material configured to conform to a body of a patient on the pad. The conduit system can be disposed in the pad body or an overlayer configured for placement over the pad body. The conduit system can include one or more conduits configured to convey a fluid through the pad body or the overlayer. The one-or-more inlets can be configured for charging the conduit system with the fluid, while the one-or-more outlets can be configured for discharging the fluid from the conduit system. Methods of the systems and pads can include methods of use. In another example, a deformable pad can be configured for receiving a neonatal patient.

Abstract: Disclosed herein are systems, pads, and methods thereof for targeted temperature management. A first pad can include a multilayered pad body and an inflatable cuff around the pad body. The pad body can include a conformable layer, a conduit layer over the conformable layer, and an insulation layer over the conduit layer. The conformable layer can include a conformable material configured to conform around a limb of a patient. The conduit layer can include one or more conduits configured to convey a fluid through the conduit layer. The insulation layer can be configured to insulate the conduit layer from an ambient temperature of an environment around the patient. The inflatable cuff can be configured to press the pad body against the limb of the patient when the inflatable cuff is inflated. Methods of the systems and pads can include methods of use.