Patents by Inventor Madhavan Nampoothiri

Madhavan Nampoothiri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9150892
    Abstract: Disclosed are processes for producing Arginine by fermentation in which sugars obtained by enzymatic starch hydrolysis from inexpensive starch containing agro-wastes, such as Cassava bagasse and Jackfruit seed powder, are fermented in the presence of microorganisms to produce a fermentated liquor containing Arginine, and recovering Arginine from the liquor. The process can economically be scaled up for the production of Arginine from unrefined sugar sources as it produced Arginine in higher yields, when compared to more expensive synthetic carbon sources, like dextrose or sucrose.
    Type: Grant
    Filed: February 25, 2010
    Date of Patent: October 6, 2015
    Assignees: Colgate-Palmolive Company, Council of Scientific and Industrial Research
    Inventors: Ashok Pandey, K. Madhavan Nampoothiri, Ravi Subramanyam
  • Publication number: 20120309061
    Abstract: Disclosed are processes for producing Arginine by fermentation in which sugars obtained by enzymatic starch hydrolysis from inexpensive starch containing agro-wastes, such as Cassava bagasse and Jackfruit seed powder, are fermented in the presence of microorganisms to produce a fermentated liquor containing Arginine, and recovering Arginine from the liquor. The process can economically be scaled up for the production of Arginine from unrefined sugar sources as it produced Arginine in higher yields, when compared to more expensive synthetic carbon sources, like dextrose or sucrose.
    Type: Application
    Filed: February 25, 2010
    Publication date: December 6, 2012
    Applicant: COLGATE-PALMOLIVE COMPANY
    Inventors: Ashok Pandey, K. Madhavan Nampoothiri, Ravi Subramanyam
  • Patent number: 6949374
    Abstract: The invention relates to a genetically modified coryneform bacterium, the fadD15 gene of which is amplified, and an isolated polynucleotide which codes for acyl-CoA synthase from coryneform bacteria, and also a method for the fermentative preparation of L-amino acids with amplification of the fadD15 gene in the bacteria and the use of the polynucleotide as a primer or hybridization probe.
    Type: Grant
    Filed: May 16, 2001
    Date of Patent: September 27, 2005
    Assignee: Degussa AG
    Inventors: Madhavan Nampoothiri K., Bettina Möckel, Walter Pfefferle, Lothar Eggeling, Hermann Sahm
  • Patent number: 6830921
    Abstract: The invention relates to an isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of a) polynucleotide which is identical to the extent of at least 70 % to a polynucleotide which codes for a polypeptide which comprises the amino acid sequence of SEQ ID No. 2, b) polynucleotide which codes for a polypeptide which comprises an amino acid sequence which is identical to the extent of at least 70 % to the amino acid sequence of SEQ ID No. 2, c) polynucleotide which is complementary to the polynucleotides of a) or b), and d) polynucleotide comprising at least 15 successive nucleotides of the polynucleotide sequence of a), b) or c), a process for the fermentative preparation of L-amino acids with enhancement of the acp gene and the use of the polynucleotide as a primer or hybridization probe.
    Type: Grant
    Filed: May 10, 2001
    Date of Patent: December 14, 2004
    Assignee: Degussa AG
    Inventors: Bettina Möckel, Anke Weissenborn, Walter Pfefferle, Hermann Sahm, Lothar Eggeling, Madhavan Nampoothiri
  • Publication number: 20040092710
    Abstract: This invention relates to a genetically modified coryneform bacterium, the cdsA gene of which is amplified, and to an isolated polynucleotide, which codes for phosphatidate cytidylyl transferase from coryneform bacteria and to a method for the fermentative production of L-amino acids with amplification of the cdsA gene in the bacteria and to the use of the polynucleotide as a primer or hybridization probe.
    Type: Application
    Filed: May 14, 2001
    Publication date: May 13, 2004
    Inventors: Madhavan Nampoothiri K., Bettina Mockel, Walter Pfefferle, Lothar Eggeling, Hermann Sahm
  • Patent number: 6680186
    Abstract: The present invention relates to polynucleotides corresponding to the plsC gene and which encode 1-acyl-SN-glycerol-3-phosphate acyltransferase, methods of producing L-amino acids, and methods of screening for polynucleotides which encode proteins having 1-acyl-SN-glycerol-3-phosphate acyltransferase activity.
    Type: Grant
    Filed: April 11, 2001
    Date of Patent: January 20, 2004
    Assignees: Degussa AG, Forschungszentrum Juelich GmbH
    Inventors: Madhavan Nampoothiri, Brigitte Bathe, Lothar Eggeling, Hermann Sahm
  • Patent number: 6638753
    Abstract: The invention relates to a genetically modified coryneform bacterium, the cma gene of which is amplified, and an isolated polynucleotide which codes for cyclopropane-mycolic acid synthase from coryneform bacteria, and also a method for the fermentative preparation of L-amino acids with amplification of the cma gene in the bacteria and the use of the polynucleotide as a primer or hydridization probe.
    Type: Grant
    Filed: May 1, 2001
    Date of Patent: October 28, 2003
    Assignees: Degussa AG, Forschungszentrum Julich GmbH
    Inventors: Madhavan Nampoothiri K., Bettina Möckel, Lothar Eggeling, Hermann Sahm
  • Patent number: 6562607
    Abstract: This invention relates to a genetically modified coryneform bacterium, the cls gene of which is amplified, and to an isolated polynucleotide, which codes for cardiolipin synthase from coryneform bacteria and to a process for the fermentative production of L-amino acids with amplification of the cls gene in the bacteria and to the use of the polynucleotide as a primer or hybridization probe.
    Type: Grant
    Filed: May 4, 2001
    Date of Patent: May 13, 2003
    Assignees: Degussa-Huls Aktiengesellschaft, Forschungszentrum Julich GmbH
    Inventors: Madhavan Nampoothiri K., Bettina Möckel, Walter Pfefferle, Lothar Eggeling, Hermann Sahm
  • Publication number: 20030003558
    Abstract: The present invention relates to polynucleotides corresponding to the plsC gene and which encode 1-acyl-SN-glycerol-3-phosphate acyltransferase, methods of producing L-amino acids, and methods of screening for polynucleotides which encode proteins having 1-acyl-SN-glycerol-3-phosphate acyltransferase activity.
    Type: Application
    Filed: April 11, 2001
    Publication date: January 2, 2003
    Applicant: DEGUSSA-HUELS AKTIENGESELLSCHAFT
    Inventors: Madhavan Nampoothiri, Brigitte Bathe, Lothar Eggeling, Hermann Sahm
  • Publication number: 20020155555
    Abstract: The invention relates to a genetically modified coryneform bacterium, the pgsA2 gene of which is amplified, and an isolated polynucleotide which codes for CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase from coryneform bacteria, and also a method for the fermentative preparation of L-amino acids with amplification of the pgsA2 gene in the bacteria and the use of the polynucleotide as a primer or hydridization probe.
    Type: Application
    Filed: May 16, 2001
    Publication date: October 24, 2002
    Inventors: Madhavan Nampoothiri K., Bettina Mockel, Walter Pfefferle, Lothar Eggeling, Hermann Sahm
  • Publication number: 20020102667
    Abstract: This invention relates to a genetically modified coryneform bacterium, the cls gene of which is amplified, and to an isolated polynucleotide, which codes for cardiolipin synthase from coryneform bacteria and to a process for the fermentative production of L-amino acids with amplification of the cls gene in the bacteria and to the use of the polynucleotide as a primer or hybridization probe.
    Type: Application
    Filed: May 4, 2001
    Publication date: August 1, 2002
    Inventors: Madhavan Nampoothiri K., Bettina Mockel, Walter Pfefferle, Lothar Eggeling, Hermann Sahm
  • Publication number: 20020055154
    Abstract: The invention relates to an isolated polynucleotide comprising a polynucleotide sequence chosen from the group consisting of
    Type: Application
    Filed: May 10, 2001
    Publication date: May 9, 2002
    Inventors: Bettina Mockel, Anke Weissenborn, Walter Pfefferle, Hermann Sahm, Lothar Eggeling, Madhavan Nampoothiri
  • Publication number: 20020042107
    Abstract: The invention relates to a genetically modified coryneform bacterium, the fadD15 gene of which is amplified, and an isolated polynucleotide which codes for acyl-CoA synthase from coryneform bacteria, and also a method for the fermentative preparation of L-amino acids with amplification of the fadD15 gene in the bacteria and the use of the polynucleotide as a primer or hybridization probe.
    Type: Application
    Filed: May 16, 2001
    Publication date: April 11, 2002
    Inventors: Madhavan Nampoothiri K., Bettina Mockel, Walter Pfefferle, Lothar Eggeling, Hermann Sahm
  • Publication number: 20020042106
    Abstract: The invention relates to a genetically modified coryneform bacterium, the cma gene of which is amplified, and an isolated polynucleotide which codes for cyclopropane-mycolic acid synthase from coryneform bacteria, and also a method for the fermentative preparation of L-amino acids with amplification of the cma gene in the bacteria and the use of the polynucleotide as a primer or hydridization probe.
    Type: Application
    Filed: May 1, 2001
    Publication date: April 11, 2002
    Inventors: Madhavan Nampoothiri K., Bettina Mockel, Lothar Eggeling, Hermann Sahm
  • Publication number: 20020034794
    Abstract: An isolated nucleic acid that encodes glycerol-3-phosphate dehydrogenase from coryneform bacteria, variants, homologs and fragments thereof. Hybridization probes and primers, vectors and host cells comprising such sequences. Coryneform bacterium with an enhanced ability to express glycerol-3-phosphate dehyrogenase. Methods of fermentative production of L-amino acids using coryneform bacteria having enhanced expression of glycerol-3-phosphate dehydrogenase.
    Type: Application
    Filed: March 2, 2001
    Publication date: March 21, 2002
    Applicant: Degussa-Huels Aktiengesellschaft
    Inventors: Madhavan Nampoothiri, Brigitte Bathe, Lothar Eggeling, Hermann Sahm