Patents by Inventor Madhavan P. Nair

Madhavan P. Nair has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • POLYOLS AND POLYOL-BASED HYDROGELS WITH ANTI-CANCER ACTIVITY
    Publication number: 20250009784
    Abstract: The present invention provides compositions and methods for selectively treating a cancer or tumor utilizing an effective amount of a vegetable oil-derived polyol or hydrogel particles comprising a vegetable oil-derived polyol. In some embodiments, the cancer is a gynecologic cancer, specifically an ovarian cancer. In other aspects, the present invention provides a method of targeting and imaging various tumors and/or tumor associated macrophages (TAMs).
    Type: Application
    Filed: April 2, 2024
    Publication date: January 9, 2025
    Applicant: THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES
    Inventors: Arti VASHIST, Andrea D. RAYMOND, Prem CHAPAGAIN, Madhavan P. NAIR, Carolyn D. RUNOWICZ
  • Absolute precipitation of exosomes (APEX) isolation
    Patent number: 12123024
    Abstract: The subject invention provides compositions and methods for isolating exosomes from, for example, biological fluid samples, cell cultures and/or cultured medium. Provided are Absolute Precipitation of Exosomes (APEX) reagents and precipitation techniques to isolate exosomes from various EV subsets, cells, dead cells, and/or cell debris. Advantageously, APEX is a rapid, effortless, inexpensive, high-recovery method to extract exosomes. This method is also faster and purer at isolating exosomes from other precipitation techniques.
    Type: Grant
    Filed: January 11, 2024
    Date of Patent: October 22, 2024
    Assignee: The Florida International University Board of Trustees
    Inventors: Andrea D. Raymond, Madhavan P. Nair, Arti Vashist, Mickensone Andre
  • Polyols and polyol-based hydrogels with anti-cancer activity
    Patent number: 11969438
    Abstract: The present invention provides compositions and methods for selectively treating a cancer or tumor utilizing an effective amount of a vegetable oil-derived polyol or hydrogel particles comprising a vegetable oil-derived polyol. In some embodiments, the cancer is a gynecologic cancer, specifically an ovarian cancer. In other aspects, the present invention provides a method of targeting and imaging various tumors and/or tumor associated macrophages (TAMs).
    Type: Grant
    Filed: July 7, 2023
    Date of Patent: April 30, 2024
    Assignee: The Florida International University Board of Trustees
    Inventors: Arti Vashist, Andrea D. Raymond, Prem Chapagain, Madhavan P. Nair, Carolyn D. Runowicz