Patents by Inventor Madhavi Kannan

Madhavi Kannan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ARTIFICIAL IMMUNOHISTOCHEMICAL IMAGE SYSTEMS AND METHODS
    Publication number: 20230145084
    Abstract: The disclosure provides a method of generating an artificial immunohistochemistry (IHC) image of cells. The method includes receiving a hematoxylin and eosin (H&E) stained whole slide image (WSI) generated by a brightfield microscopy imaging modality of at least a portion of cells included in a specimen, applying, to the H&E brightfield image, at least one trained model, the trained model being trained to generate the artificial IHC image based on the H&E brightfield image, receiving the artificial IHC image from the trained model.
    Type: Application
    Filed: January 4, 2023
    Publication date: May 11, 2023
    Inventors: Madhavi Kannan, Brian Larsen, Aly Khan, Ameen Salahudeen
  • Platform For Co-Culture Imaging To Characterize In Vitro Efficacy Of Heterotypic Effector Cellular Therapies In Cancer
    Publication number: 20230036156
    Abstract: A method for characterizing cancer organoid response to an immune cell based therapy, includes providing a panel of different combinations of cancer organoid cells and immune cells to culturing wells and culturing the different combination under conditions that support organoid growth. Brightfield and corresponding fluorescence images of the culturing wells are captured and provided to one or more trained machine learning algorithms that identify and distinguish cancer organoid cells from immune cells and characterize cancer organoid morphology changes caused by an immune cell based therapies, from which an analytical report including a characterization of cancer organoid cell death caused by the immune cell based therapy is provided.
    Type: Application
    Filed: July 29, 2022
    Publication date: February 2, 2023
    Inventors: Chi-Sing Ho, Madhavi Kannan, Sonal Khare, Brian Larsen, Brandon Mapes, Ameen Salahudeen, Jagadish Venkataraman
  • Artificial fluorescent image systems and methods
    Patent number: 11561178
    Abstract: The disclosure provides a method of generating an artificial fluorescent image of cells is provided.
    Type: Grant
    Filed: April 20, 2021
    Date of Patent: January 24, 2023
    Assignee: Tempus Labs, Inc.
    Inventors: Madhavi Kannan, Brian Larsen, Aly A. Khan, Ameen Salahudeen
  • SYSTEMS AND METHODS FOR PREDICTING THERAPEUTIC SENSITIVITY
    Publication number: 20220392640
    Abstract: Methods, systems, and software are provided for using organoid cultures, e.g., patient-derived tumor organoid cultures, to improve treatment predictions and outcomes.
    Type: Application
    Filed: October 22, 2020
    Publication date: December 8, 2022
    Inventors: Ameen Salahudeen, Brian M. Larsen, Michelle M. Stein, Luka A. Karginov, Madhavi Kannan, Aly A. Khan, Verónica Sánchez Freire, Yilin Zhang
  • LARGE SCALE ORGANOID ANALYSIS
    Publication number: 20220341914
    Abstract: Methods, systems, and software are provided for using organoid cultures, e.g., patient-derived tumor organoid cultures, to improve treatment predictions and outcomes.
    Type: Application
    Filed: July 5, 2022
    Publication date: October 27, 2022
    Inventors: Brian M. Larsen, Michelle M. Stein, Luka A. Karginov, Ameen Salahudeen, Madhavi Kannan, Aly A. Khan, Verónica Sánchez Freire, Yilin Zhang
  • Large scale organoid analysis
    Patent number: 11415571
    Abstract: Methods, systems, and software are provided for using organoid cultures, e.g., patient-derived tumor organoid cultures, to improve treatment predictions and outcomes.
    Type: Grant
    Filed: December 7, 2020
    Date of Patent: August 16, 2022
    Assignee: Tempus Labs, Inc.
    Inventors: Brian M. Larsen, Michelle M. Stein, Luka A. Karginov, Ameen Salahudeen, Madhavi Kannan, Aly A. Khan, Verónica Sánchez Freire, Yilin Zhang
  • ARTIFICIAL FLOURESCENT IMAGE SYSTEMS AND METHODS
    Publication number: 20210325308
    Abstract: The disclosure provides a method of generating an artificial fluorescent image of cells is provided.
    Type: Application
    Filed: April 20, 2021
    Publication date: October 21, 2021
    Inventors: Madhavi Kannan, Brian Larsen, Aly A. Khan, Ameen Salahudeen
  • LARGE SCALE ORGANOID ANALYSIS
    Publication number: 20210172931
    Abstract: Methods, systems, and software are provided for using organoid cultures, e.g., patient-derived tumor organoid cultures, to improve treatment predictions and outcomes.
    Type: Application
    Filed: December 7, 2020
    Publication date: June 10, 2021
    Inventors: Brian M. Larsen, Michelle M. Stein, Luka A. Karginov, Ameen Salahudeen, Madhavi Kannan, Aly A. Khan, Verónica Sánchez Freire, Yilin Zhang