Patents by Inventor Madhubabu Alapharthi

Madhubabu Alapharthi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for Preparing Ethyl (s)-2-Ethoxy-4-[N-[1-(2-Piperidinophenyl)-3-Methyl-1-Butyl]Aminocarbonyl Methyl]Benzoate and Use Thereof for the Preparation of Repaglinide
    Publication number: 20120065404
    Abstract: Described herein is an improved, commercially viable and industrially advantageous process for the preparation of Repaglinide intermediate, ethyl (S)-2-ethoxy-4-[N-(1-(2-piperidino-phenyl)-3-methyl-1-butyl)-aminocarbonylmethyl]-benzoate. The process provides the Repaglinide intermediate in higher yield and purity compared to the previously disclosed processes, thereby providing for production of Repaglinide and its pharmaceutically acceptable salts in high purity and in high yield.
    Type: Application
    Filed: November 21, 2011
    Publication date: March 15, 2012
    Applicant: ACTAVIS GROUP PTC HF
    Inventors: Venkata Sasidhar Balla, Madhubabu Alapharthi, Nitin Sharadchandra Pradhan, Jon Valgeirsson
  • Process for preparing ethyl (S)-2-ethoxy-4-[N-[1-(2-piperidinophenyl)-3-methyl-1-butyl]aminocarbonyl methyl]benzoate and use thereof for the preparation of Repaglinide
    Patent number: 8101769
    Abstract: Described herein is an improved, commercially viable and industrially advantageous process for the preparation of Repaglinide intermediate, ethyl (S)-2-ethoxy-4-[N-(1-(2-piperidino-phenyl)-3-methyl-1-butyl)-aminocarbonylmethyl]-benzoate. The process provides the Repaglinide intermediate in higher yield and purity compared to the previously disclosed processes, thereby providing for production of Repaglinide and its pharmaceutically acceptable salts in high purity and in high yield.
    Type: Grant
    Filed: February 14, 2008
    Date of Patent: January 24, 2012
    Assignee: Actavis Group PTC EHF
    Inventors: Venkata Sasidhar Balla, Madhubabu Alapharthi, Nitin Sharadchandra Pradhan, Jon Valgeirsson
  • Process for Preparing Ethyl (s)-2-Ethoxy-4-[N-[1-(2-Piperidinophenyl)-3-Methyl-1-Butyl]Aminocarbonyl Methyl]Benzoate and Use Thereof for the Preparation of Repaglinide
    Publication number: 20080200684
    Abstract: Described herein is an improved, commercially viable and industrially advantageous process for the preparation of Repaglinide intermediate, ethyl (S)-2-ethoxy-4-[N-(1-(2-piperidino-phenyl)-3-methyl-1-butyl)-aminocarbonylmethyl]-benzoate. The process provides the Repaglinide intermediate in higher yield and purity compared to the previously disclosed processes, thereby providing for production of Repaglinide and its pharmaceutically acceptable salts in high purity and in high yield.
    Type: Application
    Filed: February 14, 2008
    Publication date: August 21, 2008
    Applicant: ACTAVIS GROUP PTC hf
    Inventors: Venkata Sasidhar Balla, Madhubabu Alapharthi, Nitin Sharadchandra Pradhan, Jon Valgeirsson