Patents by Inventor Madison R. Rackear

Madison R. Rackear has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RNA-GUIDED NUCLEASES AND ACTIVE FRAGMENTS AND VARIANTS THEREOF AND METHODS OF USE
    Publication number: 20230203463
    Abstract: Compositions and methods for binding to a target sequence of interest are provided. The compositions find use in cleaving or modifying a target sequence of interest, detecting a target sequence of interest, and modifying the expression of a sequence of interest. Compositions comprise RNA-guided nuclease polypeptides, CRISPR RNAs, trans-activating CRISPR RNAs, guide RNAs, and nucleic acid molecules encoding the same. Vectors and host cells comprising the nucleic acid molecules are also provided. Further provided are CRISPR systems for binding a target sequence of interest, wherein the CRISPR system comprises an RNA-guided nuclease polypeptide and one or more guide RNAs.
    Type: Application
    Filed: December 28, 2020
    Publication date: June 29, 2023
    Applicant: LifeEDIT Therapeutics, Inc.
    Inventors: Alexandra Briner Crawley, Philip Borden, Tyson D. Bowen, Michael Coyle, Madison R. Rackear, Tedd D. Elich