Patents by Inventor Mads Nørregaard-Madsen

Mads Nørregaard-Madsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enzymatic encoding methods for efficient synthesis of large libraries
    Patent number: 11702652
    Abstract: Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).
    Type: Grant
    Filed: January 15, 2020
    Date of Patent: July 18, 2023
    Assignee: NUEVOLUTION A/S
    Inventors: Thomas Franch, Mikkel Dybro Lundorf, Søren Nyboe Jakobsen, Eva Kampmann Olsen, Anne Lee Andersen, Anette Holtmann, Anders Holm Hansen, Anders Malling Sørensen, Anne Goldbech, Daen de Leon, Ditte Kievsmose Kaldor, Frank Abildgaard Sløk, Gitte Nystrup Husemoen, Johannes Dolberg, Kim Birkebæk Jensen, Lene Petersen, Mads Nørregaard-Madsen, Michael Anders Godskesen, Sanne Schrøder Glad, Søren Neve, Thomas Thisted, Tine Titilola Akinleminu Kronborg, Christian Klarner Sams, Jakob Felding, Per-Ola Freskgard, Alex Haahr Gouliaev, Henrik Pedersen
  • ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES
    Publication number: 20200216836
    Abstract: Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).
    Type: Application
    Filed: January 15, 2020
    Publication date: July 9, 2020
    Applicant: NUEVOLUTION A/S
    Inventors: Thomas FRANCH, Mikkel Dybro LUNDORF, Søren Nyboe JAKOBSEN, Eva Kampmann OLSEN, Anne Lee ANDERSEN, Anette HOLTMANN, Anders Holm HANSEN, Anders Malling SØRENSEN, Anne GOLDBECH, Daen de LEON, Ditte Kievsmose KALDOR, Frank Abildgaard SLØK, Gitte Nystrup HUSEMOEN, Johannes DOLBERG, Kim Birkebæk JENSEN, Lene PETERSEN, Mads NØRREGAARD-MADSEN, Michael Anders GODSKESEN, Sanne Schrøder GLAD, Søren NEVE, Thomas THISTED, Tine Titilola Akinleminu KRONBORG, Christian Klarner SAMS, Jakob FELDING, Per-Ola FRESKGARD, Alex Haahr GOULIAEV, Henrik PEDERSEN
  • Templated molecules and methods for using such molecules
    Patent number: 10669538
    Abstract: The present invention relates to a method for synthesising templated molecules. In one aspect of the invention, the templated molecules are linked to the template which templated the synthesis thereof. The invention allows the generation of libraries which can be screened for e.g. therapeutic activity.
    Type: Grant
    Filed: October 13, 2016
    Date of Patent: June 2, 2020
    Assignee: NUEVOLUTION A/S
    Inventors: Henrik Pedersen, Alex Haahr Gouliaev, Thomas Franch, Christian Klarner Sams, Eva Kampmann Olsen, Frank Abilgaard Slok, Gitte Nystrup Husemoen, Jakob Felding, Lene Hyldtoft, Mads Norregaard-Madsen, Michael Anders Godskesen, Sanne Schroder Glad, Thomas Thisted, Per-Ola Freskgard, Anette Holtmann
  • ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES
    Publication number: 20190330618
    Abstract: Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).
    Type: Application
    Filed: January 22, 2019
    Publication date: October 31, 2019
    Inventors: Thomas FRANCH, Mikkel Dybro LUNDORF, Søren Nyboe JAKOBSEN, Eva Kampmann OLSEN, Anne Lee ANDERSEN, Anette HOLTMANN, Anders Holm HANSEN, Anders Malling SØRENSEN, Anne GOLDBECH, Daen de LEON, Ditte Kievsmose KALDOR, Frank Abildgaard SLØK, Gitte Nystrup HUSEMOEN, Johannes DOLBERG, Kim Birkebæk JENSEN, Lene PETERSEN, Mads NØRREGAARD-MADSEN, Michael Anders GODSKESEN, Sanne Schrøder GLAD, Søren NEVE, Thomas THISTED, Tine Titilola Akinleminu KRONBORG, Christian Klarner SAMS, Jakob FELDING, Per-Ola FRESKGARD, Alex GOULIAEV, Henrik PEDERSEN
  • Subtilase variants
    Patent number: 10351837
    Abstract: The present invention relates to subtilase variants exhibiting alterations relative to the parent subtilase in one or more properties including: wash performance, thermal stability, storage stability or catalytic activity. The subtilase variants of the invention are suitable for use in, e.g., cleaning or detergent compositions, such as laundry detergent compositions and dishwash compositions, including automatic dishwash compositions.
    Type: Grant
    Filed: November 18, 2016
    Date of Patent: July 16, 2019
    Assignee: Novozymes A/S
    Inventors: Tina Sejersgard Fano, Claus Von Der Osten, Malene Kappen Kruger, Mads Norregaard-Madsen
  • Enzymatic encoding methods for efficient synthesis of large libraries
    Patent number: 10287576
    Abstract: Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).
    Type: Grant
    Filed: December 12, 2016
    Date of Patent: May 14, 2019
    Assignee: NUEVOLUTION A/S
    Inventors: Thomas Franch, Mikkel Dybro Lundorf, Søren Nyboe Jakobsen, Eva Kampmann Olsen, Anne Lee Andersen, Anette Holtmann, Anders Holm Hansen, Anders Malling Sørensen, Anne Goldbech, Daen de Leon, Ditte Kievsmose Kaldor, Frank Abildgaard Sløk, Gitte Nystrup Husemoen, Johannes Dolberg, Kim Birkebæk Jensen, Lene Petersen, Mads Nørregaard-Madsen, Michael Anders Godskesen, Sanne Schrøder Glad, Søren Neve, Thomas Thisted, Tine Titilola Akinleminu Kronborg, Christian Klarner Sams, Jakob Felding, Per-Ola Freskgard, Alex Haahr Gouliaev, Henrik Pedersen
  • ENZYMATIC ENCODING METHODS FOR EFFICIENT SYNTHESIS OF LARGE LIBRARIES
    Publication number: 20170247688
    Abstract: Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).
    Type: Application
    Filed: December 12, 2016
    Publication date: August 31, 2017
    Applicant: NUEVOLUTION A/S
    Inventors: Thomas FRANCH, Mikkel Dybro LUNDORF, Søren Nyboe JACOBSEN, Eva Kampmann OLSEN, Anne Lee ANDERSEN, Anette HOLTMANN, Anders Holm HANSEN, Anders Malling SØRENSEN, Anne GOLDBECH, Daen de LEON, Ditte Kievsmose KALDOR, Frank Abildgaard SLØK, Gitte Nystrup HUSEMOEN, Johannes DOLBERG, Kim Birkebæk JENSEN, Lene PEDERSEN, Mads NØRREGAARD-MADSEN, Michael Anders GODSKESEN, Sanne Schrøder GLAD, Søren NEVE, Thomas THISTED, Tine Titilola Akinleminu KRONBORG, Christian Klarner SAMS, Jakob FELDING, Per-Ola FRESKGARD, Alex Haahr GOULIAEV, Henrik PEDERSEN
  • Subtilase variants
    Patent number: 9732310
    Abstract: The present invention relates to novel subtilase variants exhibiting alterations relative to the parent subtilase in one or more properties including: Wash performance, thermal stability, storage stability or catalytic activity. The variants of the invention are suitable for use in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dish wash compositions, including automatic dish wash compositions.
    Type: Grant
    Filed: December 21, 2010
    Date of Patent: August 15, 2017
    Assignee: NOVOZYMES A/S
    Inventors: Henriette Draborg, Peter Kamp Hansen, Mads Eskelund Bjornvad, Mads Norregaard-Madsen, Mikael Mikkelsen
  • TEMPLATED MOLECULES AND METHODS FOR USING SUCH MOLECULES
    Publication number: 20170198283
    Abstract: The present invention relates to a method for synthesising templated molecules. In one aspect of the invention, the templated molecules are linked to the template which templated the synthesis thereof. The invention allows the generation of libraries which can be screened for e.g. therapeutic activity.
    Type: Application
    Filed: October 13, 2016
    Publication date: July 13, 2017
    Inventors: Henrik PEDERSEN, Alex Haahr GOUILAEV, Thomas FRANCH, Christian Klarner SAMS, Eva Kampmann OLSEN, Frank Abilgaard SLOK, Gitte Nystrup HUSEMOEN, Jakob FELDING, Lene HYLDTOFT, Mads NORREGAARD-MADSEN, Michael Anders GODSKESEN, Sanne Schroder GLAD, Thomas THISTED, Per-Ola FRESKGARD, Anette HOLTMANN
  • Templated molecules and methods for using such molecules
    Patent number: 9688980
    Abstract: The present invention relates to a method for synthesising templated molecules. In one aspect of the invention, the templated molecules are linked to the template which templated the synthesis thereof. The intion allows the generation of libraries which can be screened for e.g. therapeutic activity.
    Type: Grant
    Filed: December 16, 2014
    Date of Patent: June 27, 2017
    Assignee: NUEVOLUTION
    Inventors: Henrik Pedersen, Alex Haahr Gouliaev, Thomas Franch, Christian Klarner Sams, Eva Kampmann Olsen, Frank Abilgaard Slok, Gitte Nystrup Husemoen, Jakob Felding, Lene Hyldtoft, Mads Norregaard-Madsen, Michael Anders Godskesen, Sanne Schroder Glad, Thomas Thisted, Per-Ola Freskgard, Anette Holtmann
  • Subtilase Variants
    Publication number: 20170096654
    Abstract: The present invention relates to subtilase variants exhibiting alterations relative to the parent subtilase in one or more properties including: wash performance, thermal stability, storage stability or catalytic activity. The subtilase variants of the invention are suitable for use in, e.g., cleaning or detergent compositions, such as laundry detergent compositions and dishwash compositions, including automatic dishwash compositions.
    Type: Application
    Filed: November 18, 2016
    Publication date: April 6, 2017
    Applicant: Novozymes A/S
    Inventors: Tina Sejersgard Fano, Claus Von Der Osten, Malene Kappen Kruger, Mads Norregaard-Madsen
  • Enzymatic encoding methods for efficient synthesis of large libraries
    Patent number: 9574189
    Abstract: Disclosed is a method for obtaining a bifunctional complex comprising a molecule linked to a single stranded identifier oligonucleotide, wherein a nascent bifunctional complex comprising a chemical reaction site and a priming site for enzymatic addition of a tag is a) reacted at the chemical reaction site with one or more reactants, and b) reacted enzymatically at the priming site with one or more tag(s) identifying the reactant(s).
    Type: Grant
    Filed: December 1, 2006
    Date of Patent: February 21, 2017
    Assignee: Nuevolution A/S
    Inventors: Thomas Franch, Mikkel Dybro Lundorf, Søren Nyboe Jacobsen, Eva Kampmann Olsen, Anne Lee Andersen, Anette Holtmann, Anders Holm Hansen, Anders Malling Sørensen, Anne Goldbech, Daen de Leon, Ditte Kievsmose Kaldor, Frank Abildgaard Sløk, Gitte Nystrup Husemoen, Johannes Dolberg, Kim Birkebæ Jensen, Lene Pedersen, Mads Nørregaard-Madsen, Michael Anders Godskesen, Sanne Schrøder Glad, Søren Neve, Thomas Thisted, Tine Titilola Akinleminu Kronborg, Christian Klarner Sams, Jakob Felding, Per-Ola Freskgård, Alex Haahr Gouliaev, Henrik Pedersen
  • Subtilase variants
    Patent number: 9528100
    Abstract: The present invention relates to novel subtilase variants exhibiting alterations relative to the parent subtilase in one or more properties including: Wash performance, thermal stability, storage stability or catalytic activity. The variants of the invention are suitable for use in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dishwash compositions, including automatic dishwash compositions.
    Type: Grant
    Filed: September 30, 2014
    Date of Patent: December 27, 2016
    Assignee: Novozymes A/S
    Inventors: Tina Sejersgard Fano, Claus Von Der Osten, Malene Kappen Kruger, Mads Norregaard-Madsen
  • TEMPLATED MOLECULES AND METHODS FOR USING SUCH MOLECULES
    Publication number: 20150315567
    Abstract: The present invention relates to a method for synthesising templated molecules. In one aspect of the invention, the templated molecules are linked to the template which templated the synthesis thereof. The intion allows the generation of libraries which can be screened for e.g. therapeutic activity.
    Type: Application
    Filed: December 16, 2014
    Publication date: November 5, 2015
    Inventors: Henrik PEDERSEN, Alex Haahr GOUILAEV, Thomas FRANCH, Christian Klarner SAMS, Eva Kampmann OLSEN, Frank Abilgaard SLOK, Gitte Nystrup HUSEMOEN, Jakob FELDING, Lene HYLDTOFT, Mads NORREGAARD-MADSEN, Michael Anders GODSKESEN, Sanne Schroder GLAD, Thomas THISTED, Per-Ola FRESKGARD, Anette HOLTMANN
  • Subtilase Variants
    Publication number: 20150024990
    Abstract: The present invention relates to novel subtilase variants exhibiting alterations relative to the parent subtilase in one or more properties including: Wash performance, thermal stability, storage stability or catalytic activity. The variants of the invention are suitable for use in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dishwash compositions, including automatic dishwash compositions.
    Type: Application
    Filed: September 30, 2014
    Publication date: January 22, 2015
    Inventors: Tina Sejersgard Fano, Claus Von Der Osten, Malene Kappen Kruger, Mads Norregaard-Madsen
  • Templated molecules and methods for using such molecules
    Patent number: 8932992
    Abstract: The present invention relates to a method for synthesizing templated molecules. In one aspect of the invention, the templated molecules are linked to the template which templated the synthesis thereof. The intion allows the generation of libraries which can be screened for e.g. therapeutic activity.
    Type: Grant
    Filed: December 9, 2008
    Date of Patent: January 13, 2015
    Assignee: Nuevolution A/S
    Inventors: Henrik Pedersen, Alex Haahr Gouilaev, Thomas Franch, Christian Klarner Sams, Eva Kampmann Olsen, Frank Abilgaard Sløk, Gitte Nystrup Husemoen, Jakob Felding, Lene Hyldtoft, Mads Nørregaard-Madsen, Michael Anders Godskesen, Sanne Schrøder Glad, Thomas Thisted, Per-Ola Freskgård, Anette Holtmann
  • Subtilase Variants
    Publication number: 20140018283
    Abstract: The present invention relates to novel subtilase variants exhibiting alterations relative to the parent subtilase in one or more properties including: Wash performance, thermal stability, storage stability or catalytic activity. The variants of the invention are suitable for use in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dishwash compositions, including automatic dishwash compositions.
    Type: Application
    Filed: September 24, 2013
    Publication date: January 16, 2014
    Applicant: Novozymes A/S
    Inventors: Tina Sejersgard Fano, Claus Von Der Osten, Malene Kappen Kruger, Mads Norregaard-Madsen
  • Subtilase variants
    Patent number: 8569035
    Abstract: The present invention relates to novel subtilase variants exhibiting alterations relative to the parent subtilase in one or more properties including: Wash performance, thermal stability, storage stability or catalytic activity. The variants of the invention are suitable for use in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dishwash compositions, including automatic dishwash compositions.
    Type: Grant
    Filed: April 29, 2013
    Date of Patent: October 29, 2013
    Assignee: Novozymes A/S
    Inventors: Tina Sejersgard Fano, Claus Von Der Osten, Malene Kappen Kruger, Mads Norregaard-Madsen
  • Subtilase Variants
    Publication number: 20120149624
    Abstract: The present invention relates to novel subtilase variants exhibiting alterations relative to the parent subtilase in one or more properties including: Wash performance, thermal stability, storage stability or catalytic activity. The variants of the invention are suitable for use in e.g. cleaning or detergent compositions, such as laundry detergent compositions and dish wash compositions, including automatic dish wash compositions.
    Type: Application
    Filed: December 20, 2010
    Publication date: June 14, 2012
    Applicant: Novozymes A/S
    Inventors: Henriette Draborg, Peter Kamp Hansen, Mads Eskelund Bjornvad, Mads Norregaard-Madsen, Mikael Mikkelsen
  • Proteases and variants thereof
    Patent number: 8119386
    Abstract: The present invention relates to isolated proteases of the RP-II type and variants of RP-II proteases exhibiting improved properties in comparison to the parent RP-II protease, DNA constructs and vectors coding for the expression of said proteases and variants, host cells capable of expressing the proteases and variants from the DNA constructs, as well as a method of producing them by cultivating said host cells. The proteases may advantageously be used as constituents in detergent compositions and additives, optionally in combination with other enzymes such as proteases, lipases, cellulases, amylases, peroxidases or oxidases.
    Type: Grant
    Filed: January 26, 2011
    Date of Patent: February 21, 2012
    Assignee: Novozymes Als
    Inventors: Mads Norregaard-Madsen, Peter Rahbek Ostergaard, Claus Bo Voge Christensen, Soren Flensted Lassen