Abstract: The present invention relates to a pre-filled disposable injection device and a needle cannula in combination. The prefilled disposable injection device (1) is made from a housing (2) containing a non-exchangeable cartridge (10) for storing a liquid drug sufficient for a number of injections. The proximal end of the pre-filled injection device (1) carries the dose setting button (3) and the distal end carries the needle cannula (20) having a lumen (21) through which the settable dose is expelled. The distal end (23) of the needle cannula (20) is covered by a telescopic needle covering shield (30) which shield (30) can operate between a first position covering the tip (24) of the needle cannula (20) and a second retracted position allowing an injection to be performed.

Abstract: The present invention relates to a pre-filled disposable injection device and a needle cannula in combination. The prefilled disposable injection device (1) is made from a housing (2) containing a non-exchangeable cartridge (10) for storing a liquid drug sufficient for a number of injections. The proximal end of the pre-filled injection device (1) carries the dose setting button (3) and the distal end carries the needle cannula (20) having a lumen (21) through which the settable dose is expelled. The distal end (23) of the needle cannula (20) is covered by a telescopic needle covering shield (30) which shield (30) can operate between a first position covering the tip (24) of the needle cannula (20) and a second retracted position allowing an injection to be performed.

Abstract: A method of manufacturing one of a range of autoinjectors having cartridges (600, 600?, 600?) with different preset fill volumes, the method comprising the steps of: a) providing a front body assembly (100b, 100c, 100c?, 100c?), b) providing a cartridge (600, 600?, 600?) of given fill volume, c) providing a rear body assembly (100a) comprising a spring-driven drive ram assembly (310, 320) configured to drive the piston of a held cartridge (600, 600?, 600?), d) providing a ram spacer member (400, 400?, 400?), the ram spacer member defining a spacing geometry of length dimension (X1?, X1?, X1??, XS?, XS?, XS??, XR?, XR?, XR??) selected according to the fill volume of the cartridge (600, 600?, 600?), and e) assembling a front body assembly (100b, 100c, 100c?, 100c?), the cartridge (600, 600?, 600?), the ram spacer member (400, 400?, 400?) and the rear body assembly (100a) so that the ram spacer member (400, 400?, 400?) is arranged axially between the drive ram assembly (310, 320) of the rear body assembly (100a)

Abstract: A system for optimizing a patient's basal insulin dosage regimen over time, adapted to determine from blood glucose values whether and by how much to vary a patient's present recommended amount of the insulin-containing drug in order to maintain the patient's future blood glucose level measurements within a predefined range, and wherein a given blood glucose value is disregarded if no patient-actuated operation being indicative of the administration of a dose of an insulin containing drug has been detected in a pre-defined amount of time prior to the determination of the given blood glucose value.

Abstract: A needle unit (20) comprising: a needle hub (21) comprising a needle (23) and a needle shield (22), wherein the needle hub (21) and the needle shield (22) are arranged to form a needle unit (20) where the needle hub is arranged displaceably inside the needle shield such that the needle hub is displaceable along an axis which is parallel with the longitudinal axis of the needle (23) between a shielded position and an exposed position.

Abstract: An autoinjector (100) for expelling a single dose of drug from a drug cartridge (600) including a piston (630), the autoinjector including: a base (200, 220), a needle (500) that is fixedly mounted relative to the base (200, 220), a plunger (310, 320, 400) adapted for cooperation with the piston (630), an actuating spring (330) provided as a helical compression spring arranged to act on the plunger (310, 320, 400) by exerting an axial force on the plunger to drive the piston (630) distally, and a needle shield (350, 380) axially movable relative to the base (200, 220) between an extended position and a collapsed position. The autoinjector defines a lock (320, 328, 380, 388) that is released when the needle shield (350, 380) is moved from the extended position to the collapsed position.

Abstract: A system comprising a state changing appliance and a drug delivery device, the state changing appliance comprising first interface means for rotationally locking to a first exterior portion of the drug delivery device, second interface means for rotationally locking to a second exterior portion of the drug delivery device, the first exterior portion and the second exterior portion being angularly displaceable relative to one another from a first relative position to a second relative position, which second relative position defines a set dose to be expelled by the drug delivery device, and limiter means for limiting a relative angular displacement between the first interface means and the second interface means.

Abstract: An injection device for expelling a dose of drug from a held cartridge (600) is described. A needle shield (350, 380) is axially movable relative to a base (200, 220, 230) between a proximal collapsed position and a distal extended position. A needle shield lock comprises a deflectable lock element (392) operable to prevent the needle shield (350, 380) from being moved towards the proximal collapsed position. A lock activator (402) associated with a plunger (310, 400) exerts an activation force on the deflectable lock element when the plunger assumes a final position. A biasing means (403) is arranged to act between the lock activator (402) and the deflectable lock element (392), the biasing means (403) being configured to resiliency transfer the activation force from the lock activator (402) to the deflectable lock element (392) to enable the needle shield (350, 380) to become locked in the distal extended position but only when the plunger (310, 400) assumes the final position.

Abstract: A system comprising a state changing appliance and a drug delivery device, the state changing appliance comprising first interface means for rotationally locking to a first exterior portion of the drug delivery device, second interface means for rotationally locking to a second exterior portion of the drug delivery device, the first exterior portion and the second exterior portion being angularly displaceable relative to one another from a first relative position to a second relative position, which second relative position defines a set dose to be expelled by the drug delivery device, and limiter means for limiting a relative angular displacement between the first interface means and the second interface means.

Abstract: A needle unit (20) comprising: a needle hub (21) comprising a needle (23) and a needle shield (22), wherein the needle hub (21) and the needle shield (22) are arranged to form a needle unit (20) where the needle hub is arranged displaceably inside the needle shield such that the needle hub is displaceable along an axis which is parallel with the longitudinal axis of the needle (23) between a shielded position and an exposed position.

Abstract: A method of manufacturing one of a range of autoinjectors having cartridges (600, 600?, 600?) with different preset fill volumes, the method comprising the steps of: a) providing a front body assembly (100b, 100c, 100c?, 100c?), b) providing a cartridge (600, 600?, 600?) of given fill volume, c) providing a rear body assembly (100a) comprising a spring-driven drive ram assembly (310, 320) configured to drive the piston of a held cartridge (600, 600?, 600?), d) providing a ram spacer member (400, 400?, 400?), the ram spacer member defining a spacing geometry of length dimension (X1?, X1?, X1??, XS?, XS?, XS??, XR?, XR?, XR??) selected according to the fill volume of the cartridge (600, 600?, 600?), and e) assembling a front body assembly (100b, 100c, 100c?, 100c?), the cartridge (600, 600?, 600?), the ram spacer member (400, 400?, 400?) and the rear body assembly (100a) so that the ram spacer member (400, 400?, 400?) is arranged axially between the drive ram assembly (310, 320) of the rear body assembly (100a)

Abstract: A system for optimizing a patient's basal insulin dosage regimen over time, adapted to determine from blood glucose values whether and by how much to vary a patient's present recommended amount of the insulin-containing drug in order to maintain the patient's future blood glucose level measurements within a predefined range, and wherein a given blood glucose value is disregarded if no patient-actuated operation being indicative of the administration of a dose of an insulin containing drug has been detected in a pre-defined amount of time prior to the determination of the given blood glucose value.

Abstract: An autoinjector (100) for expelling a dose of a drug from a held cartridge (600) is described. A needle shield (350, 380) is axially movable relative to a base (200, 220) between an extended position and a collapsed position to operate a trigger lock (328, 388) configured for releasably maintaining a plunger (310, 400) in an initial axial position against the force of an actuator (330). One of the needle shield (350, 380) and the base (200, 220) defines one or more contact surfaces (382) each being resiliently slideable over a respective cooperating ramp surface (212) formed in the other of the needle shield (350, 380) and the base (200, 220) to provide a resistance to movement of the needle shield (350, 380) during needle shield displacement from the extended position towards the collapsed position. A high resistance to movement is obtained in a first stage of said needle shield displacement followed by a low resistance to movement in a second stage.

Abstract: An injection device for expelling a dose of drug from a held cartridge (600) is described. A needle shield (350, 380) is axially movable relative to a base (200, 220, 230) between a proximal collapsed position and a distal extended position. A needle shield lock comprises a deflectable lock element (392) operable to prevent the needle shield (350, 380) from being moved towards the proximal collapsed position. A lock activator (402) associated with a plunger (310, 400) exerts an activation force on the deflectable lock element when the plunger assumes a final position. A biasing means (403) is arranged to act between the lock activator (402) and the deflectable lock element (392), the biasing means (403) being configured to resiliency transfer the activation force from the lock activator (402) to the deflectable lock element (392) to enable the needle shield (350, 380) to become locked in the distal extended position but only when the plunger (310, 400) assumes the final position.

Abstract: An autoinjector (100) for expelling a single dose of drug from a held cartridge (600) comprising a piston (630), the autoinjector comprising: a) a base (200, 220), b) a needle (500) that is fixedly mounted relative to the base (200, 220), c) a plunger (310, 320, 400) adapted for cooperation with the piston (630), d) an actuating spring (330) arranged to act on the plunger (310, 320, 400) to drive the piston (630) distally, and e) a needle shield (350, 380) axially movable relative to the base (200, 220) between an extended position and a collapsed position. In an initial state, a thread (325) of the plunger (310, 320, 400) engages a base thread (205) to maintain the plunger in an initial axial position. The autoinjector defines a lock (320, 328, 380, 388) that is released when the needle shield (350, 380) is moved from the extended position to the collapsed position.

Abstract: The present invention relates to a medicament injection device (100) that comprises a housing (110, 120) and an actuator (400, 500) configured for expelling medicament from a held reservoir (200) through an injection needle (250). A needle shield (150) is movable from a distal position through an intermediary position and further proximally to activate dose expelling. A carrier (300) movable within the housing (110, 120) holds the injection needle (250). A detent mechanism couples carrier (300) with the needle shield (150) as the needle shield (150) moves from the distal to the intermediary position. When the needle shield is moved further proximally the detent mechanism decouples the carrier (300) from the needle shield (150). A carrier spring device (680) is arranged between the housing (110, 120) and the carrier (300). The injection device (100) provides increased safety against potential damage to the injection needle (150) in case the injection device (100) is dropped on a hard surface.

Abstract: A system comprising a state changing appliance and a drug delivery device, the state changing appliance comprising first interface means for rotationally locking to a first exterior portion of the drug delivery device, second interface means for rotationally locking to a second exterior portion of the drug delivery device, the first exterior portion and the second exterior portion being angularly displaceable relative to one another from a first relative position to a second relative position, which second relative position defines a set dose to be expelled by the drug delivery device, and limiter means for limiting a relative angular displacement between the first interface means and the second interface means.

Abstract: The invention relates to a needle device which is made from a housing (1, 2, 3) having a distal wall (4) with a front (5). The housing further holds a compartment (21, 22) containing a liquid drug to be expelled. A needle cannula (10) for expelling the liquid drug having a distal end (1 1) and a proximal end (12) is also present, the needle cannula (10) being axially movable from a first position to a second position; The first position being a position in which the distal end (1 1) of the needle cannula (10) is retracted proximally behind the front (5) of the distal wall (4) of the housing (1, 2, 3), and wherein the proximal end (12) of the needle cannula (10) is located outside the first compartment (21, 22), and the second position being a position in which the distal end (1 1) of the needle cannula (10) is extended distally to the front (5) of the distal wall (4) of the housing (1, 2, 3), and wherein the proximal (12) end is located inside the compartment (21, 22).

Abstract: The present invention relates to a pre-filled disposable injection device and a needle cannula in combination. The prefilled disposable injection device (1) is made from a housing (2) containing a non-exchangeable cartridge (10) for storing a liquid drug sufficient for a number of injections. The proximal end of the pre-filled injection device (1) carries the dose setting button (3) and the distal end carries the needle cannula (20) having a lumen (21) through which the settable dose is expelled. The distal end (23) of the needle cannula (20) is covered by a telescopic needle covering shield (30) which shield (30) can operate between a first position covering the tip (24) of the needle cannula (20) and a second retracted position allowing an injection to be performed.

Abstract: A system for optimizing a patient's insulin treatment, comprising a drug delivery device (320) with an identifier representing information for a specific drug contained in a reservoir. An accessory device (310) comprises a blood glucose meter (BGM) and a processor programmed to determine for at least two pre-defined specific drugs a recommendation for an amount of the given drug based on a blood glucose value. The recommendation for a given pre-defined drug can be calculated when the corresponding identifier has been captured with the accessory device in a current mounted state, the recommended dose being calculated based on one or more blood glucose values, one or more patient specific parameters as well as parameters for the identified specific type of drug.