Patents by Inventor Mafalda PAGANO

Mafalda PAGANO has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • AMIDO CYCLOHEXANE ACID DERIVATIVES AS LPA RECEPTOR INHIBITORS
    Publication number: 20230250093
    Abstract: The present invention relates to compounds of general formula (I) inhibiting lysophosphatidic acid receptor 1 (LPA1), particularly the invention relates to compounds that are Ami do cyclohexane acid derivatives, methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful in the treatment of diseases or conditions associated with a dysregulation of LPA receptors, in particular fibrosis.
    Type: Application
    Filed: July 15, 2021
    Publication date: August 10, 2023
    Applicant: CHIESI FARMACEUTICI S.P.A.
    Inventors: Elisabetta ARMANI, Gabriele AMARI, Andrea RIZZI, Mafalda PAGANO, Luca RAVEGLIA, Claudia BEATO
  • THIENOPYRIMIDINE DERIVATIVES AS LPA RECEPTOR 2 INHIBITORS
    Publication number: 20230061417
    Abstract: The present invention relates to a compounds of general formula (I) inhibiting lysophosphatidic acid receptor 2 (LPA2), particularly the invention relates to compounds that are thienopyrimidine derivatives, methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful in the treatment of diseases or conditions associated with a dysregulation of LPA receptors, in particular fibrosis.
    Type: Application
    Filed: December 10, 2020
    Publication date: March 2, 2023
    Inventors: Gabriele AMARI, Elisabetta ARMANI, Mafalda PAGANO, Luca RAVEGLIA
  • QUINAZOLINE DERIVATIVES AS LPA RECEPTOR 2 INHIBITORS
    Publication number: 20230063121
    Abstract: The present invention relates to a compounds of general formula (I) inhibiting lysophosphatidic acid receptor 2 (LPA2), particularly the invention relates to compounds that are quinazoline derivatives, methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful in the treatment of diseases or conditions associated with a dysregulation of LPA receptors, in particular fibrosis.
    Type: Application
    Filed: December 10, 2020
    Publication date: March 2, 2023
    Inventors: Gabriele AMARI, Elisabetta ARMANI, Mafalda PAGANO, Luca RAVEGLIA, Marta GIULIANI, Claudia BEATO
  • AROMATIC AMIDO DERIVATIVES AS LPA RECEPTOR 2 INHIBITORS
    Publication number: 20230043672
    Abstract: The present invention relates to compounds of general formula (I) inhibiting lysophosphatidic acid receptor 2 (LPA2), particularly the invention relates to compounds that are aromatic amido derivatives, methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful in the treatment of diseases or conditions associated with a dysregulation of LPA receptors, in particular fibrosis.
    Type: Application
    Filed: December 10, 2020
    Publication date: February 9, 2023
    Inventors: Gabriele AMARI, Elisabetta ARMANI, Mafalda PAGANO, Luca RAVEGLIA, Claudia BEATO