Patents by Inventor Magdalena NAUERTH

Magdalena NAUERTH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMBINATION OF REVERSIBLE AND IRREVERSIBLE CELL LABELING FOR ANALIZING RECEPTOR-LIGAND KOFF RATE
    Publication number: 20220229054
    Abstract: The invention relates to a method of determining the dissociation rate constant (koff) of a receptor molecule R on a target cell using a combination of reversible and irreversible cell labeling. The invention further relates to a cell comprising such a receptor molecule R, wherein the cell has bound to it such a combination of cell labeling. The invention further relates to a kit and an apparatus useful in performing the methods of the invention. The invention further relates to a method of isolation a high-avidity T cell.
    Type: Application
    Filed: March 29, 2022
    Publication date: July 21, 2022
    Applicants: TECHNISCHE UNIVERSITAET MUENCHEN, JUNO THERAPEUTICS GMBH
    Inventors: Magdalena NAUERTH, Dirk BUSCH, Lothar GERMEROTH
  • Combination of reversible and irreversible cell labeling for analizing receptor-ligand krate
    Patent number: 11320431
    Abstract: The invention relates to a method of determining the dissociation rate constant (koff) of a receptor molecule R on a target cell using a combination of reversible and irreversible cell labeling. The invention further relates to a cell comprising such a receptor molecule R, wherein the cell has bound to it such a combination of cell labeling. The invention further relates to a kit and an apparatus useful in performing the methods of the invention. The invention further relates to a method of isolation a high-avidity T cell.
    Type: Grant
    Filed: June 27, 2017
    Date of Patent: May 3, 2022
    Assignees: TECHNISCHE UNIVERSITAET MUENCHEN, JUNO THERAPEUTICS GMBH
    Inventors: Magdalena Nauerth, Dirk Busch, Lothar Germeroth
  • COMBINATION OF REVERSIBLE AND IRREVERSIBLE CELL LABELING FOR ANALIZING RECEPTOR-LIGAND KOFF RATE
    Publication number: 20190227061
    Abstract: The invention relates to a method of determining the dissociation rate constant (koff) of a receptor molecule R on a target cell using a combination of reversible and irreversible cell labeling. The invention further relates to a cell comprising such a receptor molecule R, wherein the cell has bound to it such a combination of cell labeling. The invention further relates to a kit and an apparatus useful in performing the methods of the invention. The invention further relates to a method of isolation a high-avidity T cell.
    Type: Application
    Filed: June 27, 2017
    Publication date: July 25, 2019
    Applicants: TECHNISCHE UNIVERSITAET MUENCHEN, JUNO THERAPEUTICS GMBH
    Inventors: Magdalena NAUERTH, Dirk BUSCH, Lothar GERMEROTH