Patents by Inventor Magdalena Otrocka

Magdalena Otrocka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Idoxuridine and its analogs as neuroprotectans for the treatment of parkinsonism
    Patent number: 11103525
    Abstract: The invention relates to compounds that are useful in the treatment of parkinsonism, such as parkinsonism in connection with Parkinson's disease (PD); dementia with Lewy bodies (DLB); multiple system atrophy (MSA); corticobasal degeneration (CBD); or progressive supranuclear palsy (PSP). The said compounds include in particular idoxuridine and analogs thereof as well as their metabolic precursors, such as ropidoxuridine. The invention further relates to method for identifying compounds useful for the treatment of parkinsonism, said methods comprising detecting the capability of compound to increase the amount of GPR37 in cell membranes. The invention further relates to methods for the chemical synthesis of ropidoxuridine.
    Type: Grant
    Filed: February 6, 2018
    Date of Patent: August 31, 2021
    Inventors: Per Svenningsson, Lina Leinartaite, Magdalena Otrocka, Vedran Hasimbegovic, Birgitta Pettersson
  • IDOXURIDINE AND ITS ANALOGS AS NEUROPROTECTANS FOR THE TREATMENT OF PARKINSONISM
    Publication number: 20190388451
    Abstract: The invention relates to compounds that are useful in the treatment of parkinsonism, such as parkinsonism in connection with Parkinson's disease (PD); dementia with Lewy bodies (DLB); multiple system atrophy (MSA); corticobasal degeneration (CBD); or progressive supranuclear palsy (PSP). The said compounds include in particular idoxuridineand analogs thereof as well as their metabolic precursors, such as ropidoxuridine. The invention further relates to method for identifying compounds useful for the treatment of parkinsonism, said methods comprising detecting the capability of compound to increase the amount of GPR37 in cell membranes. The invention further relates to methods for the chemical synthesis of ropidoxuridine.
    Type: Application
    Filed: February 6, 2018
    Publication date: December 26, 2019
    Inventors: Per Svenningsson, Lina Leinartaite, Magdalena Otrocka, Vedran Hasimbegovic, Birgitta Pettersson