Patents by Inventor Magdalena Wodnicka

Magdalena Wodnicka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Luminescent method for determining cell oxygen consumption
    Patent number: 7338778
    Abstract: The present invention relates to methods for detection and evaluation of metabolic activity of eukaryotic and/or prokaryotic cells based upon their ability to consume dissolved oxygen. The methods utilize a luminescence detection system which makes use of the sensitivity of the luminescent emission of certain compounds to the presence of oxygen, which quenches (diminishes) the compound's luminescent emission in a concentration dependent manner. Respiring eukaryotic and/or prokaryotic cells will affect the oxygen concentration of a liquid medium in which they are immersed. Thus, this invention provides a convenient system to gather information on the presence, identification, quantification and cytotoxic activity of eukaryotic and/or prokaryotic cells by determining their effect on the oxygen concentration of the media in which they are present.
    Type: Grant
    Filed: October 4, 2004
    Date of Patent: March 4, 2008
    Assignee: Becton, Dickinson and Company
    Inventors: J. Bruce Pitner, John Jacob Hemperly, Richard D. Guarino, Magdalena Wodnicka, David T. Stitt, Gregory J. Burrell, Timothy G. Foley, Jr., Patrick Shawn Beaty
  • Device for monitoring cells
    Publication number: 20050191613
    Abstract: The present invention relates to methods for detection and evaluation of metabolic activity of eukaryotic and/or prokaryotic cells based upon their ability to consume dissolved oxygen. The methods utilize a luminescence detection system which makes use of the sensitivity of the luminescent emission of certain compounds to the presence of oxygen, which quenches (diminishes) the compound's luminescent emission in a concentration dependent manner. Respiring eukaryotic and/or prokaryotic cells will affect the oxygen concentration of a liquid medium in which they are immersed. Thus, this invention provides a convenient system to gather information on the presence, identification, quantification and cytotoxic activity of eukaryotic and/or prokaryotic cells by determining their effect on the oxygen concentration of the media in which they are present.
    Type: Application
    Filed: October 4, 2004
    Publication date: September 1, 2005
    Inventors: J. Bruce Pitner, John Jacob Hemperly, Richard Guarino, Magdalena Wodnicka, David Stitt, Gregory Burrell, Timothy Foley, Patrick Shawn Beaty
  • Device for monitoring cells
    Patent number: 6900030
    Abstract: The present invention relates to methods for detection and evaluation of metabolic activity of eukaryotic and/or prokaryotic cells based upon their ability to consume dissolved oxygen. The methods utilize a luminescence detection system which makes use of the sensitivity of the luminescent emission of certain compounds to the presence of oxygen, which quenches (diminishes) the compound's luminescent emission in a concentration dependent manner. Respiring eukaryotic and/or prokaryotic cells will affect the oxygen concentration of a liquid medium in which they are immersed. Thus, this invention provides a convenient system to gather information on the presence, identification, quantification and cytotoxic activity of eukaryotic and/or prokaryotic cells by determining their effect on the oxygen concentration of the media in which they are present.
    Type: Grant
    Filed: April 4, 2002
    Date of Patent: May 31, 2005
    Assignee: Becton, Dickinson and Company
    Inventors: J. Bruce Pitner, John Jacob Hemperly, Richard D. Guarino, Magdalena Wodnicka, David T. Stitt, Gregory J. Burrell, Timothy G. Foley, Jr., Patrick Shawn Beaty
  • Device for monitoring cells
    Publication number: 20020155424
    Abstract: The present invention relates to methods for detection and evaluation of metabolic activity of eukaryotic and/or prokaryotic cells based upon their ability to consume dissolved oxygen. The methods utilize a luminescence detection system which makes use of the sensitivity of the luminescent emission of certain compounds to the presence of oxygen, which quenches (diminishes) the compound's luminescent emission in a concentration dependent manner. Respiring eukaryotic and/or prokaryotic cells will affect the oxygen concentration of a liquid medium in which they are immersed. Thus, this invention provides a convenient system to gather information on the presence, identification, quantification and cytotoxic activity of eukaryotic and/or prokaryotic cells by determining their effect on the oxygen concentration of the media in which they are present.
    Type: Application
    Filed: April 4, 2002
    Publication date: October 24, 2002
    Inventors: J. Bruce Pitner, John Jacob Hemperly, Richard D. Guarino, Magdalena Wodnicka, David T. Stitt, Gregory J. Burrell, Timothy G. Foley, Patrick Shawn Beaty
  • Device for monitoring cells
    Patent number: 6395506
    Abstract: The present invention relates to methods for detection and evaluation of metabolic activity of eukaryotic and/or prokaryotic cells based upon their ability to consume dissolved oxygen. The methods utilize a luminescence detection system which makes use of the sensitivity of the luminescent emission of certain compounds to the presence of oxygen, which quenches (diminishes) the compound's luminescent emission in a concentration dependent manner. Respiring eukaryotic and/or prokaryotic cells will affect the oxygen concentration of a liquid medium in which they are immersed. Thus, this invention provides a convenient system to gather information on the presence, identification, quantification and cytotoxic activity of eukaryotic and/or prokaryotic cells by determining their effect on the oxygen concentration of the media in which they are present.
    Type: Grant
    Filed: June 29, 1999
    Date of Patent: May 28, 2002
    Assignee: Becton, Dickinson and Company
    Inventors: J. Bruce Pitner, John Jacob Hemperly, Richard D. Guarino, Magdalena Wodnicka, David T. Stitt, Gregory J. Burrell, Timothy G. Foley, Jr., Patrick Shawn Beaty