Patents by Inventor Magdi Habib

Magdi Habib has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220176359
    Abstract: The present invention provides a composite comprising graphene, a conjugated porous organic polymer and a metalloprotein and to methods of making the composite. The invention also relates to articles (e.g. to an electrode) comprising the composite and to uses of the composite, e.g. in heterogeneous catalysis of oxygen reduction reactions, and in oxygen sensing.
    Type: Application
    Filed: April 19, 2018
    Publication date: June 9, 2022
    Inventors: Magdi Habib YACOUB, Mohammed AL KORDI
  • Patent number: 10245244
    Abstract: Pharmaceutical formulations are described for use in the treatment of pulmonary arterial hypertension (PAH). The formulations comprise polymeric nanoparticles encapsulated within crosslinked polymeric hydrogel microparticles, wherein the polymeric nanoparticles carry a therapeutic agent suitable for treatment of PAH loaded within them (for example, prostacyclin synthetic analogs, PPAR ? agonists and NO donors). Preferred formulations are inhalable, dry powder pharmaceutical formulations, which are able to swell on administration to the lungs of a patient.
    Type: Grant
    Filed: January 9, 2015
    Date of Patent: April 2, 2019
    Assignee: HEART BIOTECH PHARMA LIMITED
    Inventors: Magdi Habib Yacoub, Ibrahim M El Sherbiny
  • Patent number: 10034837
    Abstract: Therapeutic formulations are described for use in the treatment of chronic obstructive pulmonary disease, bronchial asthma, cystic fibrosis, chlorine inhalation, influenza and acute myocardial infarction. The formulations comprise polymeric nanoparticles or polymeric nanoparticles encapsulated within cross-linked polymeric hydrogel microparticles, wherein the polymeric nanoparticles carry a therapeutic agent suitable for treatment of chronic obstructive pulmonary disease, bronchial asthma, cystic fibrosis, chlorine inhalation, influenza, acute myocardial infarction and heart failure. Preferred formulations are inhalable, dry powder therapeutic formulations, which are able to swell on administration to the lungs of a patient.
    Type: Grant
    Filed: June 24, 2016
    Date of Patent: July 31, 2018
    Assignee: HEART BIOTECH PHARMA LIMITED
    Inventors: Magdi Habib Yacoub, Ibrahim M. El-Sherbiny
  • Patent number: 9878073
    Abstract: The invention involves bioresorbable stents which elute nitric oxide (NO). The stent is comprised of three main key design elements: a bioresorbable scaffold, a bioresorbable polymeric coating layer(s), and NO-releasing nanoparticles incorporated in the bioresorbable polymeric coating layer, and optionally also in the scaffold. The NO-releasing nanoparticles are made of nontoxic biocompatible and biodegradable materials; for example a chitosan polymer and optionally a sugar.
    Type: Grant
    Filed: April 20, 2016
    Date of Patent: January 30, 2018
    Assignee: HEART BIOTECH LIMITED
    Inventors: Magdi Habib Yacoub, Ibrahim El-Sherbiny
  • Publication number: 20160374950
    Abstract: Therapeutic formulations are described for use in the treatment of chronic obstructive pulmonary disease, bronchial asthma, cystic fibrosis, chlorine inhalation, influenza and acute myocardial infarction. The formulations comprise polymeric nanoparticles or polymeric nanoparticles encapsulated within cross-linked polymeric hydrogel microparticles, wherein the polymeric nanoparticles carry a therapeutic agent suitable for treatment of chronic obstructive pulmonary disease, bronchial asthma, cystic fibrosis, chlorine inhalation, influenza, acute myocardial infarction and heart failure. Preferred formulations are inhalable, dry powder therapeutic formulations, which are able to swell on administration to the lungs of a patient.
    Type: Application
    Filed: June 24, 2016
    Publication date: December 29, 2016
    Inventors: Magdi Habib YACOUB, Ibrahim M. EL SHERBINY
  • Publication number: 20160303294
    Abstract: Disclosed herein are bioresorbable stents which elute nitric oxide (NO). The stent is comprised of three main key design elements: a bioresorbable scaffold, a bioresorbable polymeric coating layer(s), and NO-releasing nanoparticles incorporated in the bioresorbable polymeric coating layer, and optionally also in the scaffold. The NO-releasing nanoparticles are made of nontoxic biocompatible and biodegradable materials; for example a chitosan polymer and optionally a sugar.
    Type: Application
    Filed: April 20, 2016
    Publication date: October 20, 2016
    Inventors: Magdi Habib YACOUB, Ibrahim EL SHERBINY
  • Publication number: 20160303054
    Abstract: Described herein are pharmaceutical formulations for the treatment of hypercholesterolemia, comprising nanoparticles having a polymeric hydrophobic core which is associated with an inhibitor of PCSK9. The inhibitor may be EGF-A, EGF-B, or an siRNA. Preferred polymers include chitosan. The nanoparticle may further include a hydrophilic shell coating the core.
    Type: Application
    Filed: April 20, 2016
    Publication date: October 20, 2016
    Inventors: Magdi Habib YACOUB, Ibrahim EL SHERBINY
  • Publication number: 20160194378
    Abstract: Provided is a peptide and a hydrogel prepared therefrom. The peptide comprises the sequence Gly-(A)-(Gly-X-Y)m-M-(Gly-X-Y)n-Gly-(B)-Gly, wherein A and B are telopeptides, X and Y are any amino acid, m and n are integers of at least 3 and M is a receptor binding sequence. Artificial collagen derived from the peptide of the invention provides an alternative to the use of animal- or human-derived collagen in industrial, biological and biomedical applications.
    Type: Application
    Filed: March 18, 2014
    Publication date: July 7, 2016
    Inventors: Anthony Edward George CASS, Magdi Habib YACOUB
  • Patent number: 9333284
    Abstract: A ventricular assist device comprising a housing defining an interior space, at least two ports opening into said interior space, and at least one pump for pumping blood between the ports through said interior space, the ports and interior space providing a continuous blood flow path that is not interrupted by valves.
    Type: Grant
    Filed: April 4, 2013
    Date of Patent: May 10, 2016
    Assignee: Heart Biotech Limited
    Inventors: Raymond Thompson, Magdi Habib Yacoub
  • Publication number: 20150196516
    Abstract: Pharmaceutical formulations are described for use in the treatment of pulmonary arterial hypertension (PAH). The formulations comprise polymeric nanoparticles encapsulated within crosslinked polymeric hydrogel microparticles, wherein the polymeric nanoparticles carry a therapeutic agent suitable for treatment of PAH loaded within them (for example, prostacyclin synthetic analogs, PPAR ? agonists and NO donors). Preferred formulations are inhalable, dry powder pharmaceutical formulations, which are able to swell on administration to the lungs of a patient.
    Type: Application
    Filed: January 9, 2015
    Publication date: July 16, 2015
    Inventors: Magdi Habib YACOUB, Ibrahim M. EL SHERBINY
  • Publication number: 20150148897
    Abstract: A method of forming a matrix of aligned nanofibres of elevated pore size and porosity comprises spraying a polymer solution towards a rotating drum so as to form nanofibres which are collected on the drum. The matrix can be used to form artificial tissue by removing the matrix from the drum, depositing cells onto the matrix and allowing the cells to form artificial tissue. Such artificial tissue finds use in the treatment of disease or damaged tissue, and in particular in the treatment of cardiovascular disease.
    Type: Application
    Filed: November 26, 2014
    Publication date: May 28, 2015
    Inventors: Jerome Jean-Luc SOHIER, Magdi Habib Yacoub
  • Publication number: 20130289335
    Abstract: A ventricular assist device comprising a housing defining an interior space, at least two ports opening into said interior space, and at least one pump for pumping blood between the ports through said interior space, the ports and interior space providing a continuous blood flow path that is not interrupted by valves.
    Type: Application
    Filed: April 4, 2013
    Publication date: October 31, 2013
    Inventors: Raymond Thompson, Magdi Habib Yacoub
  • Publication number: 20110071337
    Abstract: A ventricular assist device comprising a housing defining an interior space, at least two ports opening into said interior space, and at least one pump for pumping blood between the ports through said interior space, the ports and interior space providing a continuous blood flow path that is not interrupted by valves.
    Type: Application
    Filed: March 26, 2008
    Publication date: March 24, 2011
    Applicant: Cardio Assist Ltd.
    Inventors: Raymond Thompson, Magdi Habib Yacoub
  • Patent number: 4688554
    Abstract: Apparatus for directing the tip of a scoping instrument having an elongated image transmitting optical system. The elongated optical system is slidably received within the tubular member of a directing cannula mechanism having a bending section at its distal end. The optical system is then held against longitudinal movement relative to the cannula mechanism at a location distant from the distal end. The cannula mechanism can be rotated on its axis for moving the tip of the optical system through 360.degree. of azimuth. A control mechanism is operable from a proximal end of the directing cannula mechanism and includes a single cable which extends through the tubular member to an annular member at the extremity of the distal end. When the desired azimuthal position of the cannula mechanism is achieved the cable is tensioned, enabling the annular member, and with it the tip of the optical system, to be deflected through an arc of 90.degree., or more.
    Type: Grant
    Filed: April 10, 1986
    Date of Patent: August 25, 1987
    Assignee: American Hospital Supply Corp.
    Inventor: Magdi Habib