Patents by Inventor Magdolna Sebestyen

Magdolna Sebestyen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds for targeting hepatocytes
    Publication number: 20060154867
    Abstract: We describe compounds that bind to and are internalized by hepatocytes. Association of these compounds to other molecules or complexes can be used to target the molecules or complexes to hepatocytes in vivo or in vitro.
    Type: Application
    Filed: January 20, 2006
    Publication date: July 13, 2006
    Inventors: Alexander Sokoloff, So Wong, Jon Wolff, Sean Monahan, James Ludtke, Lori Higgs, Darren Wakefield, Magdolna Sebestyen
  • Targeting compounds to a cell nucleus
    Publication number: 20060009411
    Abstract: We disclose gene delivery systems that target exogenous nucleic acids to the nucleus of mammalian cells and are delivered to chromatin during cellular mitosis, remaining within the nucleus after mitosis.
    Type: Application
    Filed: September 6, 2005
    Publication date: January 12, 2006
    Inventor: Magdolna Sebestyen
  • Process for the preparation of fluoromethyl-quinoline derivatives
    Patent number: 4659834
    Abstract: A process is disclosed for preparing a compound of the Formula (I) ##STR1## wherein R.sup.2 is trifluoromethyl or chloro;R.sup.3 is hydrogen or chloro; andX is halogen; wherein a compound of the Formula (II) ##STR2## wherein R.sup.5 is --CFCl.sub.2, --CF.sub.2 Cl, or --CCl.sub.3 ; andR.sup.6 is chloro or trichloromethyl;is fluoroinated either with a mixture of antimony (III) fluoride and antimony (V) chloride or bromide; or with antimony (V) fluoride; or with antimony (V) chloride and hydrogen fluoride.
    Type: Grant
    Filed: December 5, 1983
    Date of Patent: April 21, 1987
    Assignee: Alkaloida Vegyeszeti Gyar
    Inventors: Zoltan Salamon, Ilona Imre nee Virag, Magdolna Sebestyen
  • Chloromethyl quinoline derivatives and use thereof as analgesics
    Patent number: 4599345
    Abstract: A chlorinated quinoline derivative of formula (I) ##STR1## wherein R.sup.1 is --CCl.sub.3, --CF.sub.3, --CHCl.sub.2 or --CH.sub.2 Cl, R.sup.2 is hydrogen when R.sup.3 is not hydrogen, or is halogen, C.sub.1-4 alkoxy, C.sub.1-4 alkyl or R.sup.1, R.sup.3 is hydrogen when R.sup.2 is not hydrogen or is halogen, C.sub.1-4 alkyl, C.sub.1-4 alkoxy or CF.sub.3, R.sup.6 is hydrogen or halogen, X is halogen. The compounds are made by chlorination of selected compounds as disclosed and the new compounds can have antimicrobial, antifungal or analgesic effects.
    Type: Grant
    Filed: December 1, 1983
    Date of Patent: July 8, 1986
    Assignee: Alkaloide Vegyeszeti Gyar
    Inventors: Zoltan Salamon, Ilona Imre nee Virag, Magdolna Sebestyen