Abstract: The present application relates to process for preparation of Mavacamten, preparative methods of various crystalline forms of Mavacamten and amorphous form of Mavacamten, its preparative method, and pharmaceutical compositions thereof. The present application also relates to solid dispersions of Mavacamten, their preparative methods and pharmaceutical compositions containing solid dispersions of Mavacamten.

Abstract: Aspects of the present application relate to process for the preparation of Omecamtiv mecarbil and salts thereof. Specific aspects relate to novel urea intermediate, preparative process thereof and its use in the preparation of Omecamtiv mecarbil and salts thereof. The improved process for the preparation of Omecamtiv mecarbil are industrially viable.

Abstract: Aspects of the present application relate to process for the preparation of Pyrrolidine derivatives useful as key intermediates for active ingredients. Specific aspects relate to alternate process for the preparation of Upadacitinib intermediate, 4-ethylpyrrolidine-3-carboxylic acid, its ester or a salt thereof. Processes disclosed here in are cost effective and industrially viable as compared to known processes.

Abstract: Disclosed are methods and apparatus for network wide discovery of service ports of a gateway device in a storage area network (SAN) that are available for use by hosts on a first particular network segment, for example, for accessing storage devices in the SAN. The hosts of the first Internet Protocol (IP) network segment implement an IP and not a fiber channel protocol, while devices in the SAN (and possibly other hosts on other network segments) implement a fiber channel protocol. The particular network segment may also be isolated from other network segments that are each in communication with a different gateway device or set of service ports than the first network segment. In general, available ports are discovered with respect to a particular network segment, such as the first network segment. That is, only the service ports that are capable of communication with the first network segment are discovered to be available for the hosts of such first network segment.