Patents by Inventor Maggie Zeng

Maggie Zeng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Medical device with crystalline drug coating
    Patent number: 9056152
    Abstract: A medical device having a polymer-free outer surface layer comprising a crystalline drug selected from the group consisting of everolimus, tacrolimus, sirolimus, zotarolimus, biolimus, and rapamycin. The device may be produced by a method comprising the steps of providing a medical device; applying a solution of the drug to said portion of the outer surface to form a coating of amorphous drug; and vapor annealing the drug with a solvent vapor to form crystalline drug; wherein a seed layer of a crystalline form of said drug having a maximum particle size of about 10 ?m or less is applied to at least said portion of the outer surface of the device before or after applying the drug solution, but before vapor annealing the amorphous coating.
    Type: Grant
    Filed: September 23, 2011
    Date of Patent: June 16, 2015
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Steve Kangas, James Feng, Yen-Lane Chen, Maggie Zeng
  • Methods of converting amorphous drug substance into crystalline form
    Patent number: 8669360
    Abstract: A method for converting an amorphous drug, such as everolimus, or other macrolide immunosuppressive drug, into a crystalline form. The method utilizes a slurry of the drug in organic liquid phase and ages the slurry to achieve the conversion.
    Type: Grant
    Filed: September 23, 2011
    Date of Patent: March 11, 2014
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Maggie Zeng, Yen-Lane Chen, Maura Romanshek, Erin Meyer
  • Medical Device with Crystalline Drug Coating
    Publication number: 20130053947
    Abstract: A medical device having a polymer-free outer surface layer comprising a crystalline drug selected from the group consisting of everolimus, tacrolimus, sirolimus, zotarolimus, biolimus, and rapamycin. The device may be produced by a method comprising the steps of providing a medical device; applying a solution of the drug to said portion of the outer surface to form a coating of amorphous drug; and vapor annealing the drug with a solvent vapor to form crystalline drug; wherein a seed layer of a crystalline form of said drug having a maximum particle size of about 10 ?m or less is applied to at least said portion of the outer surface of the device before or after applying the drug solution, but before vapor annealing the amorphous coating.
    Type: Application
    Filed: September 23, 2011
    Publication date: February 28, 2013
    Applicant: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Steve Kangas, James Feng, Yen-Lane Chen, Maggie Zeng
  • METHODS OF CONVERTING AMORPHOUS DRUG SUBSTANCE INTO CRYSTALLINE FORM
    Publication number: 20130035483
    Abstract: A method for converting an amorphous drug, such as everolimus, or other macrolide immunosuppressive drug, into a crystalline form. The method utilizes a slurry of the drug in organic liquid phase and ages the slurry to achieve the conversion.
    Type: Application
    Filed: September 23, 2011
    Publication date: February 7, 2013
    Applicant: Boston Scientific Scimed, Inc.
    Inventors: Maggie Zeng, Yen-Lane Chen, Maura Romanshek, Erin Meyer