Abstract: There are disclosed certain octahydrofuro[3,4-b]pyrazines of formula (1a), and pharmaceutically acceptable salts thereof, together with compositions containing them and their use in therapy. The compounds are GLP-1 receptor modulators and are thereby particularly useful in the treatment or prophylaxis of cardiovascular disease and metabolic conditions, for example Type 2 diabetes.

Abstract: The invention relates to a garment sorting system and method for sorting garments arranged on garment carriers. The system comprises a first transporting conveyor arrangement (5) arranged to receive a garment carrier from a pairing station which transports the garment carriers to an identification and sorting arrangement on a second conveyor arrangement comprising an identification device arranged to identify a garment carrier from an identification code for further sorting. For each garment carrier, a sorting rail address is requested by the identification and sorting arrangement from a garment identification database. The identified garment carrier is transported to a plurality of sorting rails, where the second transporting conveyor arrangement comprises a sorting interface for each sorting rail such that the identified garment carrier is moved from the second transporting conveyor arrangement to the correct sorting rail by operation of the corresponding sorting interface.

Abstract: There are disclosed certain 2,5-diazabicyclo[4.2.0]octanes of formula (I) and octahydrofuro[3,4-b]pyrazines, and pharmaceutically acceptable salts thereof, together with compositions containing them and their use in therapy. The compounds are GLP-1 receptor modulators and are thereby particularly useful in the treatment or prophylaxis of cardiovascular disease and metabolic conditions, for example Type 2 diabetes.

Abstract: There are disclosed certain 3-azabicyclo[3.1.0]hexanes, and pharmaceutically acceptable salts thereof, together with compositions containing them and their use in therapy. The compounds are GLP-1 receptor modulators and are thereby particularly useful in the treatment or prophylaxis of cardiovascular disease and metabolic conditions, for example Type 2 diabetes.

Abstract: There are disclosed certain 3-azabicyclo[3.1.0]hexanes, and pharmaceutically acceptable salts thereof, together with compositions containing them and their use in therapy. The compounds are GLP-1 receptor modulators and are thereby particularly useful in the treatment or prophylaxis of cardiovascular disease and metabolic conditions, for example Type 2 diabetes.

Abstract: There are disclosed certain 2,5-diazabicyclo[4.2.0]octanes of formula (I), and pharmaceutically acceptable salts thereof, together with compositions containing them and their use in therapy. The compounds are GLP-1 receptor modulators and are thereby particularly useful in the treatment or prophylaxis of cardiovascular disease and metabolic conditions, for example Type 2 diabetes.

Abstract: The invention relates to a garment sorting system and method for sorting garments arranged on garment carriers. The system comprises a first transporting conveyor arrangement arranged to receive a garment carrier from a pairing station which transports the garment carriers to an identification and sorting arrangement on a second conveyor arrangement comprising an identification device arranged to identify a garment carrier from an identification code for further sorting. For each garment carrier, a sorting rail address is requested by the identification and sorting arrangement from a garment identification database. The identified garment carrier is transported to a plurality of sorting rails, where the second transporting conveyor arrangement comprises a sorting interface for each sorting rail such that the identified garment carrier is moved from the second transporting conveyor arrangement to the correct sorting rail by operation of the corresponding sorting interface.

Abstract: A pump for delivering a fluid includes a pump housing that defines at least one reservoir having a circumferentially open first end, a circumferentially closed second end and a chamber to receive the fluid. The pump includes a plunger assembly having at least one plunger arm and a cannula fluidly coupled to the plunger arm to dispense the fluid from the pump. The plunger arm is receivable within the first end of the reservoir, and the at least one plunger arm defining an internal conduit to receive the fluid from the at least one fluid reservoir. The internal conduit is fluidly coupled to the cannula. The plunger assembly is movable in a first direction relative to the pump housing to advance the plunger arm within the fluid reservoir to dispense the fluid from the fluid reservoir out of the pump via the cannula.

Abstract: Embodiments of the present disclosure provide a method, a first node, a second node, and a computer program product for providing an interruption free communication, in a wireless communication network. The method is performed by a second node in the wireless communication network. The method includes detecting that one or more management operations are to be executed at the second node, the execution of the one or more management operations causing an interruption of the wireless communication to from a user equipment. Upon detecting that the one or more management operations are to be executed at the second node, the method includes receiving an indication from one or more first nodes, the indication indicating to the second node whether or not to execute the one or more management operations. Further, the method includes determining to execute the one or more management operations based on the received indication.

Abstract: Heating chamber for a portable stove comprises a fixation mechanism for securing, in a leak-free manner, a container such as a bottle to a first surface of the heating chamber; one or more compartments fillable with liquid, typically water, dispensed from the container; a pressure compensation valve; and an outlet configured to release the liquid from the heating chamber.

Abstract: The disclosure relates to a lining for a haul truck body, said lining being arranged to extend over a haul truck body for carrying a load, wherein the lining is formed by a plurality of lining elements comprising at least a first type of lining elements, termed load-breaking lining elements, and a second type of lining elements, different from the load-breaking lining elements, said load-breaking lining elements being structured and arranged to restrict, to a higher degree than the second type of lining elements, movement of said load in relation to the lining. The disclosure further relates to a haul truck body comprising the lining and a haul truck comprising the haul truck body.

Abstract: A wearable infusion port for infusing a fluid includes a first housing that defines an inlet port to receive the fluid, and a second housing coupled to the first housing. The second housing is to be coupled to an anatomy. The wearable infusion port includes a valve assembly fluidly coupled to the inlet port, and the valve assembly is movable from a closed state to an opened state to dispense the fluid. The wearable infusion port includes a cannula assembly extending through the first housing and the second housing, and the cannula assembly includes a cannula fluidly coupled to the valve assembly. The cannula is to be coupled to the anatomy. The wearable infusion port includes a flow sensor fluidly coupled to the inlet port and the cannula. The flow sensor is fluidly coupled upstream from the cannula to observe an amount of fluid received by the cannula.

Abstract: A portable outdoor stove comprises a gas control valve, the gas control valve being dockable by a fuel supply means; a burner unit provided on the gas control valve; a plurality of supports attached to the portable outdoor stove, the supports being foldable at least between a first position and a second position; wherein in the first position, the supports are adapted to provide a hold for a receptacle such as a pot to be heated by the burner unit; wherein in the second position, the supports are adapted to form a cover around the burner unit such that the burner unit does not project outside the cover.

Abstract: A pump for delivering a fluid includes a pump housing that defines at least one reservoir having a circumferentially open first end, a circumferentially closed second end and a chamber to receive the fluid. The pump includes a plunger assembly having at least one plunger arm and a cannula fluidly coupled to the plunger arm to dispense the fluid from the pump. The plunger arm is receivable within the first end of the reservoir, and the at least one plunger arm defining an internal conduit to receive the fluid from the at least one fluid reservoir. The internal conduit is fluidly coupled to the cannula. The plunger assembly is movable in a first direction relative to the pump housing to advance the plunger arm within the fluid reservoir to dispense the fluid from the fluid reservoir out of the pump via the cannula.

Abstract: Medical devices and related patient management systems and methods are provided. A method of monitoring a plurality of patients involves a computing device obtaining measurement data for the plurality of patients from a database, obtaining one or more prioritization rules from the database, generating a prioritized list of the plurality of patients based on the measurement data in accordance with the one or more prioritization rules, and providing a dashboard graphical user interface (GUI) display including the prioritized list. The prioritized list on the dashboard GUI display is dynamically updated in accordance with the prioritization rule(s) in response to updated measurement data in the database.

Abstract: The disclosure relates to a lining for a haul truck body, said lining being arranged to extend over surfaces of said haul truck body, wherein said surfaces define at least one impact region and at least one wear region; wherein said lining within said at least one impact region presents one or more impact lining elements; wherein said lining within said at least one wear region presents one or more wear lining elements; and wherein said impact lining elements have a higher impact resistance than said wear lining elements and said wear lining elements have a higher wear resistance than the impact lining elements. The disclosure further relates to a haul truck body comprising the lining and a haul truck comprising the haul truck body.

Abstract: A neurostimulation device, external programmer, or remote programming device may receive blood flow information relating to blood flow values from one or more blood flow sensing devices, either directly or via network connections, and perform, direct or control, based on the blood flow information, generation of neurostimulation efficacy information, information to assist in programming of one or more neurostimulation parameter, and/or automatic control of one or more neurostimulation stimulation parameters.

Abstract: A pump for delivering a fluid includes a pump housing that defines at least one reservoir having a circumferentially open first end, a circumferentially closed second end and a chamber to receive the fluid. The pump includes a plunger assembly having at least one plunger arm and a cannula fluidly coupled to the plunger arm to dispense the fluid from the pump. The plunger arm is receivable within the first end of the reservoir, and the at least one plunger arm defining an internal conduit to receive the fluid from the at least one fluid reservoir. The internal conduit is fluidly coupled to the cannula. The plunger assembly is movable in a first direction relative to the pump housing to advance the plunger arm within the fluid reservoir to dispense the fluid from the fluid reservoir out of the pump via the cannula.

Abstract: An electronic device (12) in a cluster (10) that has the potential to serve as a new cluster head (36) receives cluster head assistance data from a current cluster head (36) device. The cluster head assistance data includes at least one data item related to establishment of operative communication with the wireless communications network (28) over a network communications interface (26) of the electronic device. If the electronic device is assigned to be the new cluster head, it injects the at least one data item into a process related to operation of the network communications interface and establishment of the operative communication with the wireless communications network; establishes the operative communication with the wireless communications network; and carries out cluster head functions on behalf of the cluster.