Abstract: Present invention relates to a novel treatment regimen for cancer.

Abstract: A method of treating a bacterial infection in a subject includes administering at least a first finely divided (particulate) material, which may have at least a second material, the first material is not bioresorbable or very slowly bioresorable and the second material or materials are bioresorbable at a higher rate than the first material, allowing a certain period of time to pass in order to provide for the first particulate material to be exposed to the body and/or second material or materials to be wholly or partly absorbed by the body of the subject, and administering one or more pharmaceutically active compounds. The first material is optionally pre-loaded or soaked with one or more pharmaceutically active compounds, and the second material is optionally pre-loaded or soaked with one or more pharmaceutically active compounds. The pharmaceutically active compound is a compound capable of treating or ameliorating a bacterial infection.

Abstract: A method of treating a bacterial infection in a subject includes administering at least a first finely divided (particulate) material, which may have at least a second material, the first material is not bioresorbable or very slowly bioresorable and the second material or materials are bioresorbable at a higher rate than the first material, allowing a certain period of time to pass in order to provide for the first particulate material to be exposed to the body and/or second material or materials to be wholly or partly absorbed by the body of the subject, and administering one or more pharmaceutically active compounds. The first material is optionally pre-loaded or soaked with one or more pharmaceutically active compounds, and the second material is optionally pre-loaded or soaked with one or more pharmaceutically active compounds. The pharmaceutically active compound is a compound capable of treating or ameliorating a bacterial infection.

Abstract: A method for bone healing or treatment of bone fracture in a subject includes optionally pre-drilling a hole or creating a cavity in a body tissue, implanting a device onto or into the body tissue, or at least partially inserting a device into the cavity or hole, administering a composition into the device and/or near the device. The composition includes a first finely divided particulate material, and can optionally include at least a second material. The first material is not bioresorbable or is very slowly bioresorbable and the second material or materials are bioresorbable at a higher rate than the first material. The method can optionally include fully inserting the device into the hole or cavity, and can optionally include administering a pharmaceutical composition to the subject.

Abstract: Present invention relates to a novel composition administering pharma agents using a bi-phasic recruiting moiety.

Abstract: A biosensor for detecting a biomarker in a bodily fluid, secretion or exudation is described that includes a first electrode, a second electrode, an electrode coating and a mechanical electrode stabilizer. The biomarker is an enzyme catalyzing a chemical reaction in which a singularity or plurality of constituents of the electrode coating are chemically altered by the breaking of covalent chemical bonds when being in contact with the same. The electrode coating can be a natural or synthetic substrate of the biomarker. The first electrode and the second electrode are electrically conductive and are kept in a substantially constant and uniform distance from each other by means of the mechanical electrode stabilizer. The exposed electrically conductive surface of at least one of the first electrode and the second electrode are substantially fully covered by the electrode coating.

Abstract: A joint surface replacement or joint prosthesis for the distal radioulnar (DRU) joint. A complete surface replacement comprises two parts, a radial component (1) and an ulnar component (2), both of which are designed to be inserted radially relative the radius (6) and the ulna (7). The radial (1) and ulnar (2) components are constructed to assure that the concave surface of the radial component may be pivoted and translated around the convex surface of the ulnar component during rotational movement of the forearm. Either component may be singularly implanted when there is no deterioration of the mating component. By providing these components in a range of thicknesses and lengths, more effective stabilization of such joint is possible.

Abstract: A joint surface replacement or joint prosthesis for the distal radioulnar (DRU) joint. A complete surface replacement comprises two parts, a radial component (1) and an ulnar component (2), both of which are designed to be inserted radially relative the radius (6) and the ulna (7). The radial (1) and ulnar (2) components are constructed to assure that the concave surface of the radial component may be pivoted and translated around the convex surface of the ulnar component during rotational movement of the forearm. Either component may be singularly implanted when there is no deterioration of the mating component. By providing these components in a range of thicknesses and lengths, more effective stabilization of such joint is possible.