Patents by Inventor Mah Lee Mary Ng

Mah Lee Mary Ng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Human monoclonal antibody with specificity for dengue virus serotype 1 E protein and uses thereof
    Patent number: 10294293
    Abstract: Compositions and methods for the treatment or prevention of Dengue virus infection in a vertebrate subject are provided. In particular, human neutralizing monoclonal antibodies to Dengue virus isolated from EBV immortalized B cells derived from patients who have recovered from Dengue infection are disclosed. Methods are provided for administering such antibodies to a vertebrate subject in an amount effective to reduce, eliminate, or prevent relapse from infection.
    Type: Grant
    Filed: June 1, 2016
    Date of Patent: May 21, 2019
    Assignees: National University of Singapore, DSO National Laboratories
    Inventors: Paul Anthony Macary, Ee Ping Evelyn Teoh, Brendon John Hanson, En Wei Teo, Angeline Pei Chiew Lim, Mah Lee Mary Ng, Shee Mei Lok, Petra Eveliina Kukkaro
  • APTAMERS FOR BINDING FLAVIVIRUS PROTEINS
    Publication number: 20170226511
    Abstract: The present invention relates to nucleic acids. In particular, it relates to aptamers capable of binding to a flavivirus structural protein or a flavivirus non-structural protein, useful as therapeutics for preventing, treating and/or diagnosing a flavivirus infection in a patient.
    Type: Application
    Filed: November 13, 2014
    Publication date: August 10, 2017
    Applicant: National University of Singapore
    Inventors: Mah Lee Mary NG, Krupakar PARTHASARATHY, Jin Shun Anthony CHUA, Hui Yu Haydan YEO
  • BIOTINYLATED PROTEIN
    Publication number: 20170158742
    Abstract: Disclosed are methods of screening a library of molecules to identify or select one or more molecules which selectively bind to a fused protein, or fragment thereof. The fused protein comprises a moiety and a protein selected from a group consisting of flavivirus structural and non-structural (NS) proteins. The method comprises contacting the library of molecules with the fused protein and detecting binding of one or more molecules to the fused protein.
    Type: Application
    Filed: December 13, 2016
    Publication date: June 8, 2017
    Inventors: Mah Lee Mary NG, Krupakar PARTHASARATHY, Mun Keat CHONG
  • HUMAN MONOCLONAL ANTIBODY WITH SPECIFICITY FOR DENGUE VIRUS SEROTYPE 1 E PROTEIN AND USES THEREOF
    Publication number: 20170029489
    Abstract: Compositions and methods for the treatment or prevention of Dengue virus infection in a vertebrate subject are provided. In particular, human neutralizing monoclonal antibodies to Dengue virus isolated from EBV immortalized B cells derived from patients who have recovered from Dengue infection are disclosed. Methods are provided for administering such antibodies to a vertebrate subject in an amount effective to reduce, eliminate, or prevent relapse from infection.
    Type: Application
    Filed: June 1, 2016
    Publication date: February 2, 2017
    Inventors: Paul Anthony Macary, Ee Ping Evelyn Teoh, Brendon John Hanson, En Wei Teo, Angeline Pei Chiew Lim, Mah Lee Mary Ng, Shee Mei Lok, Petra Eveliina Kukkaro
  • Human monoclonal antibody with specificity for Dengue virus serotype 1 E protein and uses thereof
    Patent number: 9376486
    Abstract: Compositions and methods for the treatment or prevention of Dengue virus infection in a vertebrate subject are provided. In particular, human neutralizing monoclonal antibodies to Dengue virus isolated from EBV immortalized B cells derived from patients who have recovered from Dengue infection are disclosed. Methods are provided for administering such antibodies to a vertebrate subject in an amount effective to reduce, eliminate, or prevent relapse from infection.
    Type: Grant
    Filed: December 14, 2011
    Date of Patent: June 28, 2016
    Assignees: National University of Singapore, DSO National Laboratories
    Inventors: Paul Anthony Macary, Ee Ping Evelyn Teoh, Brendon John Hanson, En Wei Teo, Angeline Pei Chiew Lim, Mah Lee Mary Ng, Shee Mei Lok, Petra Eveliina Kukkaro
  • BIOTINYLATED PROTEIN
    Publication number: 20150291664
    Abstract: The present invention relates to a fused protein. In particular, it relates to biotinylated protein comprising a protein selected from a group consisting of flavivirus structural and non-structural (NS) proteins.
    Type: Application
    Filed: November 22, 2013
    Publication date: October 15, 2015
    Applicant: National University of Singapore
    Inventors: Mah Lee Mary Ng, Krupakar Parthasarathy, Mun Keat Chong
  • Human Monoclonal Antibody with Specificity for Dengue Virus Serotype 1 E Protein and Uses Thereof
    Publication number: 20130259871
    Abstract: Compositions and methods for the treatment or prevention of Dengue virus infection in a vertebrate subject are provided. In particular, human neutralizing monoclonal antibodies to Dengue virus isolated from EBV immortalized B cells derived from patients who have recovered from Dengue infection are disclosed. Methods are provided for administering such antibodies to a vertebrate subject in an amount effective to reduce, eliminate, or prevent relapse from infection.
    Type: Application
    Filed: December 14, 2011
    Publication date: October 3, 2013
    Applicants: DSO NATIONAL LABORATORIES, NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Paul Anthony Macary, Ee Ping Evelyn Teoh, Brendon John Hanson, En Wei Teo, Angeline Pei Chiew Lim, Mah Lee Mary Ng, Shee Mei Lok, Petra Eveliina Kukkaro