Patents by Inventor Maha El-Sayed

Maha El-Sayed has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260152642
    Abstract: Aqueous coating compositions are disclosed that are capable of forming residual antimicrobial coatings having improved performance related to residual efficacy and duration. In various embodiments, an antimicrobial coating composition comprises at least one antimicrobial compound, at least one durable matrix forming compound, and optionally, at least one performance-enhancing additive. The antimicrobial compound is selected from non-silane quaternary compounds and quaternary silanes. The durable matrix forming compound is selected from polymers, non-polymeric organic compounds, inorganic substances, additional antimicrobial substances, reactive silanes, and non-reactive silanes. The performance-enhancing additive is selected from a polymer, a solvent, an inorganic substance, a surfactant, a crosslinker, a surface modifier, and chemical species capable of forming a sol-gel.
    Type: Application
    Filed: July 30, 2025
    Publication date: June 4, 2026
    Applicant: SRFC BIO, INC.
    Inventors: Parham Asgari, Robert Godfroid, Maha El-Sayed, Valerie Beck, Devin Whorton
  • Publication number: 20230108533
    Abstract: Aqueous coating compositions are disclosed that are capable of forming residual antimicrobial coatings having improved performance related to residual efficacy and duration. In various embodiments, an antimicrobial coating composition comprises at least one antimicrobial compound, at least one durable matrix forming compound, and optionally, at least one performance-enhancing additive. The antimicrobial compound is selected from non-silane quaternary compounds and quaternary silanes. The durable matrix forming compound is selected from polymers, non-polymeric organic compounds, inorganic substances, additional antimicrobial substances, reactive silanes, and non-reactive silanes. The performance-enhancing additive is selected from a polymer, a solvent, an inorganic substance, a surfactant, a crosslinker, a surface modifier, and chemical species capable of forming a sol-gel.
    Type: Application
    Filed: October 6, 2022
    Publication date: April 6, 2023
    Applicant: SRFC BIO, INC.
    Inventors: Parham Asgari, Robert Godfroid, Maha El-Sayed, Valerie Beck, Devin Whorton
  • Publication number: 20220397561
    Abstract: Systems, indicator wipe product, and methods thereof used to detect the presence of cationic polymer residues on a surface are described. In various embodiments, the cationic polymer to be detected comprises a quaternary silane residual antimicrobial. The indicator wipe may comprise a woven, nonwoven, or double-knit fabric, cotton, functional cellulose, or open cell foam material substrate impregnated with an aqueous dye solution comprising a sulfonephthalein dye. The indicator wipe may be configured to differentiate between traditional monomer quaternary ammonium compounds and cationic polymers such as quaternary silane compounds used in residual antimicrobial coatings by color changes on the indicator wipe and by observing if cationic-dye complexes diffuse by chromatography on the indicator wipe.
    Type: Application
    Filed: June 1, 2022
    Publication date: December 15, 2022
    Applicant: SRFC BIO, INC.
    Inventors: Parham Asgari, Robert Godfroid, Jie Fang, Devin Whorton, Maha El-Sayed
  • Patent number: 11442032
    Abstract: A method of quantifying an antimicrobial coatings using a handheld XRF analyzer is disclosed. The method provides an estimate of the expected level of antimicrobial efficacy for a thin film comprising silicon and/or titanium by obtaining a 14Si or 22Ti peak intensity using XRF spectroscopy and converting the obtained 14Si or 22Ti peak intensity to the expected level of efficacy using a calibration curve. A properly calibrated handheld XRF analyzer allows a user to assess the viability of antimicrobial coatings in the field, such as in a hospital where various fomites may be coated with silane and/or titanium compositions.
    Type: Grant
    Filed: April 19, 2021
    Date of Patent: September 13, 2022
    Assignee: SRFC BIO, INC.
    Inventors: Parham Asgari, Jie Fang, Gavri Grossman, Maha El-Sayed
  • Patent number: 11369114
    Abstract: Aqueous antimicrobial coating compositions are disclosed comprising at least one organosilane homopolymer, present as a distribution of polymer chain lengths, and optionally at least one amine. A method of preparing an antimicrobial coating comprises coating a surface with the aqueous antimicrobial coating composition and allowing the composition to dry into a film that exhibits residual antimicrobial efficacy against microorganisms even after mechanical abrasion of the coating. The organosilane homopolymer may comprise only 3-aminopropylsilanetriol homopolymer, mixtures of 3-aminopropylsilanetriol homopolymer, 3-chloropropylsilanetriol homopolymer and 3-(trihydroxysilyl)propyl dimethyloctadecyl ammonium chloride homopolymer, or any one of various unique organosilane homopolymers having multiple amine functionality.
    Type: Grant
    Filed: February 17, 2021
    Date of Patent: June 28, 2022
    Assignee: Allied Bioscience, Inc.
    Inventors: Gavri Grossman, Jie Fang, Parham Asgari, Maha El-Sayed, Craig Grossman, Daniel Moros
  • Publication number: 20210267208
    Abstract: An aqueous antimicrobial coating composition capable of forming an antimicrobial coating on a surface comprises at least two organosilanes, each of the at least two organosilanes having a structure, R—Si(OR?)3 wherein R=—(CH2)3—Y; Y=+—N(CH3)2(C18H37)X?; +—N(CH3)2(C14H29)X?; +—N(C10H21)2(CH3)X?; —Cl or —NH2; X?=halide, sulfate, nitrate, phosphate, carbonate, organic sulfonate, organic carbonate, BF4?, or ClO4?; and R?=H, methyl or ethyl, or a C3-C6 straight-chained, branched or cyclic alkyl group, with the proviso that the organosilane R—Si(OR?)3 having the C3-C6 straight-chained, branched or cyclic alkyl group hydrolyzes in the aqueous antimicrobial coating composition to R—Si(OH)3.
    Type: Application
    Filed: May 10, 2021
    Publication date: September 2, 2021
    Applicant: ALLIED BIOSCIENCE, INC.
    Inventors: Gavri Grossman, Jie Fang, Parham Asgari, Maha El-Sayed, Valerie Beck, Elias Shaheen
  • Publication number: 20210239630
    Abstract: A method of quantifying an antimicrobial coatings using a handheld XRF analyzer is disclosed. The method provides an estimate of the expected level of antimicrobial efficacy for a thin film comprising silicon and/or titanium by obtaining a 14Si or 22Ti peak intensity using XRF spectroscopy and converting the obtained 14Si or 22Ti peak intensity to the expected level of efficacy using a calibration curve. A properly calibrated handheld XRF analyzer allows a user to assess the viability of antimicrobial coatings in the field, such as in a hospital where various fomites may be coated with silane and/or titanium compositions.
    Type: Application
    Filed: April 19, 2021
    Publication date: August 5, 2021
    Applicant: Allied Bioscience, Inc.
    Inventors: Parham Asgari, Jie Fang, Gavri Grossman, Maha El-Sayed
  • Publication number: 20210195902
    Abstract: An aqueous antimicrobial coating composition capable of forming an antimicrobial coating on a surface comprises at least two organosilanes, each of the at least two organosilanes having a structure, R—Si(OR?)3 wherein R=—(CH2)3—Y; Y=+—N(CH3)2(C18H37)X?; +—N(CH3)2(C14H29)X?; +—N(C10H21)2(CH3)X?; —Cl or —NH2; X?=halide, sulfate, nitrate, phosphate, carbonate, organic sulfonate, organic carbonate, BF4?, or ClO4; and R?=H, methyl or ethyl, or a C3-C6 straight-chained, branched or cyclic alkyl group, with the proviso that the organosilane R—Si(OR?)3 having the C3-C6 straight-chained, branched or cyclic alkyl group hydrolyzes in the aqueous antimicrobial coating composition to R—Si(OH)3.
    Type: Application
    Filed: March 12, 2021
    Publication date: July 1, 2021
    Applicant: ALLIED BIOSCIENCE, INC.
    Inventors: Gavri Grossman, Jie Fang, Parham Asgari, Maha El-Sayed, Valerie Beck, Elias Shaheen
  • Patent number: 11033031
    Abstract: An aqueous antimicrobial coating composition capable of forming an antimicrobial coating on a surface comprises at least two organosilanes, each of the at least two organosilanes having a structure, R—Si(OR?)3 wherein R=—(CH2)3—Y; Y=+—N(CH3)2(C18H37)X?; +—N(CH3)2(C14H29)X?; +—N(C10H21)2(CH3)X?; —Cl or —NH2; X?=halide, sulfate, nitrate, phosphate, carbonate, organic sulfonate, organic carbonate, BF4?, or ClO4?; and R?=H, methyl or ethyl, or a C3-C6 straight-chained, branched or cyclic alkyl group, with the proviso that the organosilane R—Si(OR?)3 having the C3-C6 straight-chained, branched or cyclic alkyl group hydrolyzes in the aqueous antimicrobial coating composition to R—Si(OH)3.
    Type: Grant
    Filed: March 12, 2021
    Date of Patent: June 15, 2021
    Assignee: ALLIED BIOSCIENCE, INC.
    Inventors: Gavri Grossman, Jie Fang, Parham Asgari, Maha El-Sayed, Valerie Beck, Elias Shaheen
  • Publication number: 20210169081
    Abstract: Aqueous antimicrobial coating compositions are disclosed comprising at least one organosilane homopolymer, present as a distribution of polymer chain lengths, and optionally at least one amine. A method of preparing an antimicrobial coating comprises coating a surface with the aqueous antimicrobial coating composition and allowing the composition to dry into a film that exhibits residual antimicrobial efficacy against microorganisms even after mechanical abrasion of the coating. The organosilane homopolymer may comprise only 3-aminopropylsilanetriol homopolymer, mixtures of 3-aminopropylsilanetriol homopolymer, 3-chloropropylsilanetriol homopolymer and 3-(trihydroxysilyl)propyl dimethyloctadecyl ammonium chloride homopolymer, or any one of various unique organosilane homopolymers having multiple amine functionality.
    Type: Application
    Filed: February 17, 2021
    Publication date: June 10, 2021
    Applicant: ALLIED BIOSCIENCE, INC.
    Inventors: Gavri Grossman, Jie Fang, Parham Asgari, Maha El-Sayed, Craig Grossman, Daniel Moros
  • Patent number: 11029266
    Abstract: A method of quantifying an antimicrobial coatings using a handheld XRF analyzer is disclosed. The method provides an estimate of the expected level of antimicrobial efficacy for a thin film comprising silicon and/or titanium by obtaining a 14Si or 22Ti peak intensity using XRF spectroscopy and converting the obtained 14Si or 22Ti peak intensity to the expected level of efficacy using a calibration curve. A properly calibrated handheld XRF analyzer allows a user to assess the viability of antimicrobial coatings in the field, such as in a hospital where various fomites may be coated with silane and/or titanium compositions.
    Type: Grant
    Filed: January 22, 2020
    Date of Patent: June 8, 2021
    Assignee: ALLIED BIOSCIENCE, INC.
    Inventors: Parham Asgari, Jie Fang, Gavri Grossman, Maha El-Sayed
  • Patent number: 10993441
    Abstract: Aqueous antimicrobial coating compositions are disclosed comprising at least one organosilane homopolymer, present as a distribution of polymer chain lengths, and optionally at least one amine. A method of preparing an antimicrobial coating comprises coating a surface with the aqueous antimicrobial coating composition and allowing the composition to dry into a film that exhibits residual antimicrobial efficacy against microorganisms even after mechanical abrasion of the coating. The organosilane homopolymer may comprise only 3-aminopropylsilanetriol homopolymer, mixtures of 3-aminopropylsilanetriol homopolymer, 3-chloropropylsilanetriol homopolymer and 3-(trihydroxysilyl)propyl dimethyloctadecyl ammonium chloride homopolymer, or any one of various unique organosilane homopolymers having multiple amine functionality.
    Type: Grant
    Filed: October 3, 2019
    Date of Patent: May 4, 2021
    Assignee: ALLIED BIOSCIENCE, INC.
    Inventors: Gavri Grossman, Jie Fang, Parham Asgari, Maha El-Sayed, Craig Grossman, Daniel Moros
  • Patent number: 10980236
    Abstract: An aqueous antimicrobial coating composition capable of forming an antimicrobial coating on a surface comprises at least two organosilanes, each of the at least two organosilanes having a structure, R—Si(OR?)3 wherein R=—(CH2)3—Y; Y=+—N(CH3)2(C18H37)X?; +—N(CH3)2(C14H29)X?; +—N(C10H21)2(CH3)X?; —Cl or —NH2; X?=halide, sulfate, nitrate, phosphate, carbonate, organic sulfonate, organic carbonate, BF4?, or ClO4?; and R?=H, methyl or ethyl, or a C3-C6 straight-chained, branched or cyclic alkyl group, with the proviso that the organosilane R—Si(OR?)3 having the C3-C6 straight-chained, branched or cyclic alkyl group hydrolyzes in the aqueous antimicrobial coating composition to R—Si(OH)3.
    Type: Grant
    Filed: July 27, 2020
    Date of Patent: April 20, 2021
    Assignee: ALLIED BIOSCIENCE, INC.
    Inventors: Gavri Grossman, Jie Fang, Parham Asgari, Maha El-Sayed, Valerie Beck, Elias Shaheen
  • Publication number: 20200352170
    Abstract: An aqueous antimicrobial coating composition capable of forming an antimicrobial coating on a surface comprises at least two organosilanes, each of the at least two organosilanes having a structure, R—Si(OR?)3 wherein R=—(CH2)3—Y; Y=+—N(CH3)2(C18H37)X?; +—N(CH3)2(C14H29)X?; +—N(C10H21)2(CH3)X?; —Cl or —NH2; X?=halide, sulfate, nitrate, phosphate, carbonate, organic sulfonate, organic carbonate, BF4?, or ClO4?; and R?=H, methyl or ethyl, or a C3-C6 straight-chained, branched or cyclic alkyl group, with the proviso that the organosilane R—Si(OR?)3 having the C3-C6 straight-chained, branched or cyclic alkyl group hydrolyzes in the aqueous antimicrobial coating composition to R—Si(OH)3.
    Type: Application
    Filed: July 27, 2020
    Publication date: November 12, 2020
    Applicant: ALLIED BIOSCIENCE, INC.
    Inventors: Gavri Grossman, Jie Fang, Parham Asgari, Maha El-Sayed, Valerie Beck, Elias Shaheen
  • Publication number: 20200240935
    Abstract: A method of quantifying an antimicrobial coatings using a handheld XRF analyzer is disclosed. The method provides an estimate of the expected level of antimicrobial efficacy for a thin film comprising silicon and/or titanium by obtaining a 14Si or 22Ti peak intensity using XRF spectroscopy and converting the obtained 14Si or 22Ti peak intensity to the expected level of efficacy using a calibration curve. A properly calibrated handheld XRF analyzer allows a user to assess the viability of antimicrobial coatings in the field, such as in a hospital where various fomites may be coated with silane and/or titanium compositions.
    Type: Application
    Filed: January 22, 2020
    Publication date: July 30, 2020
    Inventors: Parham Asgari, Jie Fang, Gavri Grossman, Maha El-Sayed
  • Publication number: 20200068897
    Abstract: Aqueous antimicrobial coating compositions are disclosed comprising at least one organosilane homopolymer, present as a distribution of polymer chain lengths, and optionally at least one amine. A method of preparing an antimicrobial coating comprises coating a surface with the aqueous antimicrobial coating composition and allowing the composition to dry into a film that exhibits residual antimicrobial efficacy against microorganisms even after mechanical abrasion of the coating. The organosilane homopolymer may comprise only 3-aminopropylsilanetriol homopolymer, mixtures of 3-aminopropylsilanetriol homopolymer, 3-chloropropylsilanetriol homopolymer and 3-(trihydroxysilyl)propyl dimethyloctadecyl ammonium chloride homopolymer, or any one of various unique organosilane homopolymers having multiple amine functionality.
    Type: Application
    Filed: October 3, 2019
    Publication date: March 5, 2020
    Applicant: ALLIED BIOSCIENCE, INC.
    Inventors: Gavri Grossman, Jie Fang, Parham Asgari, Maha El-Sayed, Craig Grossman
  • Patent number: 7968348
    Abstract: Provided is sampling and testing device for the detection of specific molds, allergens, viruses, bacteria, fungi, and other protein containing substances. Embodiments of the device include a sampling member slideably engaged with a base that contains a lateral flow strip adapted to detect specific analytes of interest. The sampling member defines a solvent reservoir that stores an elution solvent in a fluid-tight manner before the device is used to sample and test environmental surfaces. During slideable withdrawal of the sampling member from the base, the elution solvent stored in the reservoir is automatically released to a wick assembly of the sampling member. The wick assembly includes a wick adapted to receive, distribute, and retain the elution solvent. After a user samples an environmental surface for an analyte of interest with the elution solvent wetted wick, the sampling member is returned to the base where the wick contacts the lateral flow strip contained in the base.
    Type: Grant
    Filed: November 20, 2008
    Date of Patent: June 28, 2011
    Assignee: The Clorox Company
    Inventors: Brendi M. Cumberland, Maha El-Sayed, Alan J. Fujii, Scott D Manske, Elias A. Shaheen
  • Publication number: 20090165228
    Abstract: A cleaning implement with a handle and a removable cleaning pad can be used to effectively clean surfaces. The cleaning pad is impregnated with an acidic cleaning composition. The cleaning pad may be dry to the touch. The cleaning implement may be a manual tool or a motorized tool. Examples of suitable cleaning implements include a hard surface floor mop, a carpet mop, an auto cleaning device, a toilet cleaning device, a bathroom cleaning device, and a shower cleaning device.
    Type: Application
    Filed: December 5, 2008
    Publication date: July 2, 2009
    Inventors: Andrew Kilkenny, Maha El-Sayed, Lafayette D. Foland, Shona L. Nelson, Cheryl Rodriguez, David R. Scheuing
  • Publication number: 20090148342
    Abstract: This invention generally relates to compositions and method of producing diluted hypohalous acid and hypohalous acid vapor. These compositions can be used to treat allergen containing surfaces, hard surfaces, food contact surfaces, hospital surfaces, food surfaces, kitchen surfaces, bathroom surfaces, human surfaces, animal surfaces, children's items, outdoor surfaces, soft surfaces, and medical instruments. These compositions can be converted to solid particulate or granular compositions. These compositions can be put into a variety of containers which preserve the stability. These compositions can be used to treat allergens and molds and as part of a mold detection system. These compositions can be dispersed into the air to enable microbiological control.
    Type: Application
    Filed: October 29, 2007
    Publication date: June 11, 2009
    Inventors: Steven E. Bromberg, Bruce K. Bitowft, Elizabeth Crane, Maha El-Sayed, Daniel A. Huitt, Andreas Nguyen, Ricardo Ruiz de Gopegui, Doris S. Shieh, William L. Smith, Julie Timberman, Aram Garabedian, Lachelle Arnt, Elias A. Shaheen, Steven Bromberg, Vicki Friedman, Jennifer Fung, Jennifer C. Julian, Kenneth Vieira, Julie Wiesman, Timothy Kennedy, Chih Chiang, Kenneth L. Vieira, Maria G. Ochomogo, Scott Cumberland, Daniel Aaron Huitt, Diane Mellett, Nikhil Dani, Maha Y. El-Sayed, Lafayette D. Foland, Jorge Robles, Elias A. Shaheen
  • Publication number: 20090075250
    Abstract: Provided is sampling and testing device for the detection of specific molds, allergens, viruses, bacteria, fungi, and other protein containing substances. Embodiments of the device include a sampling member slideably engaged with a base that contains a lateral flow strip adapted to detect specific analytes of interest. The sampling member defines a solvent reservoir that stores an elution solvent in a fluid-tight manner before the device is used to sample and test environmental surfaces. During slideable withdrawal of the sampling member from the base, the elution solvent stored in the reservoir is automatically released to a wick assembly of the sampling member. The wick assembly includes a wick adapted to receive, distribute, and retain the elution solvent. After a user samples an environmental surface for an analyte of interest with the elution solvent wetted wick, the sampling member is returned to the base where the wick contacts the lateral flow strip contained in the base.
    Type: Application
    Filed: November 20, 2008
    Publication date: March 19, 2009
    Applicant: The Clorox Company
    Inventors: Brendi M. Cumberland, Maha El-Sayed, Alan J. Fujii, Scott D. Manske, Elias A. Shaheen