Patents by Inventor Maha El-Sayed
Maha El-Sayed has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20260152642Abstract: Aqueous coating compositions are disclosed that are capable of forming residual antimicrobial coatings having improved performance related to residual efficacy and duration. In various embodiments, an antimicrobial coating composition comprises at least one antimicrobial compound, at least one durable matrix forming compound, and optionally, at least one performance-enhancing additive. The antimicrobial compound is selected from non-silane quaternary compounds and quaternary silanes. The durable matrix forming compound is selected from polymers, non-polymeric organic compounds, inorganic substances, additional antimicrobial substances, reactive silanes, and non-reactive silanes. The performance-enhancing additive is selected from a polymer, a solvent, an inorganic substance, a surfactant, a crosslinker, a surface modifier, and chemical species capable of forming a sol-gel.Type: ApplicationFiled: July 30, 2025Publication date: June 4, 2026Applicant: SRFC BIO, INC.Inventors: Parham Asgari, Robert Godfroid, Maha El-Sayed, Valerie Beck, Devin Whorton
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Publication number: 20230108533Abstract: Aqueous coating compositions are disclosed that are capable of forming residual antimicrobial coatings having improved performance related to residual efficacy and duration. In various embodiments, an antimicrobial coating composition comprises at least one antimicrobial compound, at least one durable matrix forming compound, and optionally, at least one performance-enhancing additive. The antimicrobial compound is selected from non-silane quaternary compounds and quaternary silanes. The durable matrix forming compound is selected from polymers, non-polymeric organic compounds, inorganic substances, additional antimicrobial substances, reactive silanes, and non-reactive silanes. The performance-enhancing additive is selected from a polymer, a solvent, an inorganic substance, a surfactant, a crosslinker, a surface modifier, and chemical species capable of forming a sol-gel.Type: ApplicationFiled: October 6, 2022Publication date: April 6, 2023Applicant: SRFC BIO, INC.Inventors: Parham Asgari, Robert Godfroid, Maha El-Sayed, Valerie Beck, Devin Whorton
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Publication number: 20220397561Abstract: Systems, indicator wipe product, and methods thereof used to detect the presence of cationic polymer residues on a surface are described. In various embodiments, the cationic polymer to be detected comprises a quaternary silane residual antimicrobial. The indicator wipe may comprise a woven, nonwoven, or double-knit fabric, cotton, functional cellulose, or open cell foam material substrate impregnated with an aqueous dye solution comprising a sulfonephthalein dye. The indicator wipe may be configured to differentiate between traditional monomer quaternary ammonium compounds and cationic polymers such as quaternary silane compounds used in residual antimicrobial coatings by color changes on the indicator wipe and by observing if cationic-dye complexes diffuse by chromatography on the indicator wipe.Type: ApplicationFiled: June 1, 2022Publication date: December 15, 2022Applicant: SRFC BIO, INC.Inventors: Parham Asgari, Robert Godfroid, Jie Fang, Devin Whorton, Maha El-Sayed
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Patent number: 11442032Abstract: A method of quantifying an antimicrobial coatings using a handheld XRF analyzer is disclosed. The method provides an estimate of the expected level of antimicrobial efficacy for a thin film comprising silicon and/or titanium by obtaining a 14Si or 22Ti peak intensity using XRF spectroscopy and converting the obtained 14Si or 22Ti peak intensity to the expected level of efficacy using a calibration curve. A properly calibrated handheld XRF analyzer allows a user to assess the viability of antimicrobial coatings in the field, such as in a hospital where various fomites may be coated with silane and/or titanium compositions.Type: GrantFiled: April 19, 2021Date of Patent: September 13, 2022Assignee: SRFC BIO, INC.Inventors: Parham Asgari, Jie Fang, Gavri Grossman, Maha El-Sayed
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Patent number: 11369114Abstract: Aqueous antimicrobial coating compositions are disclosed comprising at least one organosilane homopolymer, present as a distribution of polymer chain lengths, and optionally at least one amine. A method of preparing an antimicrobial coating comprises coating a surface with the aqueous antimicrobial coating composition and allowing the composition to dry into a film that exhibits residual antimicrobial efficacy against microorganisms even after mechanical abrasion of the coating. The organosilane homopolymer may comprise only 3-aminopropylsilanetriol homopolymer, mixtures of 3-aminopropylsilanetriol homopolymer, 3-chloropropylsilanetriol homopolymer and 3-(trihydroxysilyl)propyl dimethyloctadecyl ammonium chloride homopolymer, or any one of various unique organosilane homopolymers having multiple amine functionality.Type: GrantFiled: February 17, 2021Date of Patent: June 28, 2022Assignee: Allied Bioscience, Inc.Inventors: Gavri Grossman, Jie Fang, Parham Asgari, Maha El-Sayed, Craig Grossman, Daniel Moros
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Publication number: 20210267208Abstract: An aqueous antimicrobial coating composition capable of forming an antimicrobial coating on a surface comprises at least two organosilanes, each of the at least two organosilanes having a structure, R—Si(OR?)3 wherein R=—(CH2)3—Y; Y=+—N(CH3)2(C18H37)X?; +—N(CH3)2(C14H29)X?; +—N(C10H21)2(CH3)X?; —Cl or —NH2; X?=halide, sulfate, nitrate, phosphate, carbonate, organic sulfonate, organic carbonate, BF4?, or ClO4?; and R?=H, methyl or ethyl, or a C3-C6 straight-chained, branched or cyclic alkyl group, with the proviso that the organosilane R—Si(OR?)3 having the C3-C6 straight-chained, branched or cyclic alkyl group hydrolyzes in the aqueous antimicrobial coating composition to R—Si(OH)3.Type: ApplicationFiled: May 10, 2021Publication date: September 2, 2021Applicant: ALLIED BIOSCIENCE, INC.Inventors: Gavri Grossman, Jie Fang, Parham Asgari, Maha El-Sayed, Valerie Beck, Elias Shaheen
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Publication number: 20210239630Abstract: A method of quantifying an antimicrobial coatings using a handheld XRF analyzer is disclosed. The method provides an estimate of the expected level of antimicrobial efficacy for a thin film comprising silicon and/or titanium by obtaining a 14Si or 22Ti peak intensity using XRF spectroscopy and converting the obtained 14Si or 22Ti peak intensity to the expected level of efficacy using a calibration curve. A properly calibrated handheld XRF analyzer allows a user to assess the viability of antimicrobial coatings in the field, such as in a hospital where various fomites may be coated with silane and/or titanium compositions.Type: ApplicationFiled: April 19, 2021Publication date: August 5, 2021Applicant: Allied Bioscience, Inc.Inventors: Parham Asgari, Jie Fang, Gavri Grossman, Maha El-Sayed
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Publication number: 20210195902Abstract: An aqueous antimicrobial coating composition capable of forming an antimicrobial coating on a surface comprises at least two organosilanes, each of the at least two organosilanes having a structure, R—Si(OR?)3 wherein R=—(CH2)3—Y; Y=+—N(CH3)2(C18H37)X?; +—N(CH3)2(C14H29)X?; +—N(C10H21)2(CH3)X?; —Cl or —NH2; X?=halide, sulfate, nitrate, phosphate, carbonate, organic sulfonate, organic carbonate, BF4?, or ClO4; and R?=H, methyl or ethyl, or a C3-C6 straight-chained, branched or cyclic alkyl group, with the proviso that the organosilane R—Si(OR?)3 having the C3-C6 straight-chained, branched or cyclic alkyl group hydrolyzes in the aqueous antimicrobial coating composition to R—Si(OH)3.Type: ApplicationFiled: March 12, 2021Publication date: July 1, 2021Applicant: ALLIED BIOSCIENCE, INC.Inventors: Gavri Grossman, Jie Fang, Parham Asgari, Maha El-Sayed, Valerie Beck, Elias Shaheen
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Patent number: 11033031Abstract: An aqueous antimicrobial coating composition capable of forming an antimicrobial coating on a surface comprises at least two organosilanes, each of the at least two organosilanes having a structure, R—Si(OR?)3 wherein R=—(CH2)3—Y; Y=+—N(CH3)2(C18H37)X?; +—N(CH3)2(C14H29)X?; +—N(C10H21)2(CH3)X?; —Cl or —NH2; X?=halide, sulfate, nitrate, phosphate, carbonate, organic sulfonate, organic carbonate, BF4?, or ClO4?; and R?=H, methyl or ethyl, or a C3-C6 straight-chained, branched or cyclic alkyl group, with the proviso that the organosilane R—Si(OR?)3 having the C3-C6 straight-chained, branched or cyclic alkyl group hydrolyzes in the aqueous antimicrobial coating composition to R—Si(OH)3.Type: GrantFiled: March 12, 2021Date of Patent: June 15, 2021Assignee: ALLIED BIOSCIENCE, INC.Inventors: Gavri Grossman, Jie Fang, Parham Asgari, Maha El-Sayed, Valerie Beck, Elias Shaheen
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Publication number: 20210169081Abstract: Aqueous antimicrobial coating compositions are disclosed comprising at least one organosilane homopolymer, present as a distribution of polymer chain lengths, and optionally at least one amine. A method of preparing an antimicrobial coating comprises coating a surface with the aqueous antimicrobial coating composition and allowing the composition to dry into a film that exhibits residual antimicrobial efficacy against microorganisms even after mechanical abrasion of the coating. The organosilane homopolymer may comprise only 3-aminopropylsilanetriol homopolymer, mixtures of 3-aminopropylsilanetriol homopolymer, 3-chloropropylsilanetriol homopolymer and 3-(trihydroxysilyl)propyl dimethyloctadecyl ammonium chloride homopolymer, or any one of various unique organosilane homopolymers having multiple amine functionality.Type: ApplicationFiled: February 17, 2021Publication date: June 10, 2021Applicant: ALLIED BIOSCIENCE, INC.Inventors: Gavri Grossman, Jie Fang, Parham Asgari, Maha El-Sayed, Craig Grossman, Daniel Moros
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Patent number: 11029266Abstract: A method of quantifying an antimicrobial coatings using a handheld XRF analyzer is disclosed. The method provides an estimate of the expected level of antimicrobial efficacy for a thin film comprising silicon and/or titanium by obtaining a 14Si or 22Ti peak intensity using XRF spectroscopy and converting the obtained 14Si or 22Ti peak intensity to the expected level of efficacy using a calibration curve. A properly calibrated handheld XRF analyzer allows a user to assess the viability of antimicrobial coatings in the field, such as in a hospital where various fomites may be coated with silane and/or titanium compositions.Type: GrantFiled: January 22, 2020Date of Patent: June 8, 2021Assignee: ALLIED BIOSCIENCE, INC.Inventors: Parham Asgari, Jie Fang, Gavri Grossman, Maha El-Sayed
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Patent number: 10993441Abstract: Aqueous antimicrobial coating compositions are disclosed comprising at least one organosilane homopolymer, present as a distribution of polymer chain lengths, and optionally at least one amine. A method of preparing an antimicrobial coating comprises coating a surface with the aqueous antimicrobial coating composition and allowing the composition to dry into a film that exhibits residual antimicrobial efficacy against microorganisms even after mechanical abrasion of the coating. The organosilane homopolymer may comprise only 3-aminopropylsilanetriol homopolymer, mixtures of 3-aminopropylsilanetriol homopolymer, 3-chloropropylsilanetriol homopolymer and 3-(trihydroxysilyl)propyl dimethyloctadecyl ammonium chloride homopolymer, or any one of various unique organosilane homopolymers having multiple amine functionality.Type: GrantFiled: October 3, 2019Date of Patent: May 4, 2021Assignee: ALLIED BIOSCIENCE, INC.Inventors: Gavri Grossman, Jie Fang, Parham Asgari, Maha El-Sayed, Craig Grossman, Daniel Moros
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Patent number: 10980236Abstract: An aqueous antimicrobial coating composition capable of forming an antimicrobial coating on a surface comprises at least two organosilanes, each of the at least two organosilanes having a structure, R—Si(OR?)3 wherein R=—(CH2)3—Y; Y=+—N(CH3)2(C18H37)X?; +—N(CH3)2(C14H29)X?; +—N(C10H21)2(CH3)X?; —Cl or —NH2; X?=halide, sulfate, nitrate, phosphate, carbonate, organic sulfonate, organic carbonate, BF4?, or ClO4?; and R?=H, methyl or ethyl, or a C3-C6 straight-chained, branched or cyclic alkyl group, with the proviso that the organosilane R—Si(OR?)3 having the C3-C6 straight-chained, branched or cyclic alkyl group hydrolyzes in the aqueous antimicrobial coating composition to R—Si(OH)3.Type: GrantFiled: July 27, 2020Date of Patent: April 20, 2021Assignee: ALLIED BIOSCIENCE, INC.Inventors: Gavri Grossman, Jie Fang, Parham Asgari, Maha El-Sayed, Valerie Beck, Elias Shaheen
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Publication number: 20200352170Abstract: An aqueous antimicrobial coating composition capable of forming an antimicrobial coating on a surface comprises at least two organosilanes, each of the at least two organosilanes having a structure, R—Si(OR?)3 wherein R=—(CH2)3—Y; Y=+—N(CH3)2(C18H37)X?; +—N(CH3)2(C14H29)X?; +—N(C10H21)2(CH3)X?; —Cl or —NH2; X?=halide, sulfate, nitrate, phosphate, carbonate, organic sulfonate, organic carbonate, BF4?, or ClO4?; and R?=H, methyl or ethyl, or a C3-C6 straight-chained, branched or cyclic alkyl group, with the proviso that the organosilane R—Si(OR?)3 having the C3-C6 straight-chained, branched or cyclic alkyl group hydrolyzes in the aqueous antimicrobial coating composition to R—Si(OH)3.Type: ApplicationFiled: July 27, 2020Publication date: November 12, 2020Applicant: ALLIED BIOSCIENCE, INC.Inventors: Gavri Grossman, Jie Fang, Parham Asgari, Maha El-Sayed, Valerie Beck, Elias Shaheen
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Publication number: 20200240935Abstract: A method of quantifying an antimicrobial coatings using a handheld XRF analyzer is disclosed. The method provides an estimate of the expected level of antimicrobial efficacy for a thin film comprising silicon and/or titanium by obtaining a 14Si or 22Ti peak intensity using XRF spectroscopy and converting the obtained 14Si or 22Ti peak intensity to the expected level of efficacy using a calibration curve. A properly calibrated handheld XRF analyzer allows a user to assess the viability of antimicrobial coatings in the field, such as in a hospital where various fomites may be coated with silane and/or titanium compositions.Type: ApplicationFiled: January 22, 2020Publication date: July 30, 2020Inventors: Parham Asgari, Jie Fang, Gavri Grossman, Maha El-Sayed
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Publication number: 20200068897Abstract: Aqueous antimicrobial coating compositions are disclosed comprising at least one organosilane homopolymer, present as a distribution of polymer chain lengths, and optionally at least one amine. A method of preparing an antimicrobial coating comprises coating a surface with the aqueous antimicrobial coating composition and allowing the composition to dry into a film that exhibits residual antimicrobial efficacy against microorganisms even after mechanical abrasion of the coating. The organosilane homopolymer may comprise only 3-aminopropylsilanetriol homopolymer, mixtures of 3-aminopropylsilanetriol homopolymer, 3-chloropropylsilanetriol homopolymer and 3-(trihydroxysilyl)propyl dimethyloctadecyl ammonium chloride homopolymer, or any one of various unique organosilane homopolymers having multiple amine functionality.Type: ApplicationFiled: October 3, 2019Publication date: March 5, 2020Applicant: ALLIED BIOSCIENCE, INC.Inventors: Gavri Grossman, Jie Fang, Parham Asgari, Maha El-Sayed, Craig Grossman
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Patent number: 7968348Abstract: Provided is sampling and testing device for the detection of specific molds, allergens, viruses, bacteria, fungi, and other protein containing substances. Embodiments of the device include a sampling member slideably engaged with a base that contains a lateral flow strip adapted to detect specific analytes of interest. The sampling member defines a solvent reservoir that stores an elution solvent in a fluid-tight manner before the device is used to sample and test environmental surfaces. During slideable withdrawal of the sampling member from the base, the elution solvent stored in the reservoir is automatically released to a wick assembly of the sampling member. The wick assembly includes a wick adapted to receive, distribute, and retain the elution solvent. After a user samples an environmental surface for an analyte of interest with the elution solvent wetted wick, the sampling member is returned to the base where the wick contacts the lateral flow strip contained in the base.Type: GrantFiled: November 20, 2008Date of Patent: June 28, 2011Assignee: The Clorox CompanyInventors: Brendi M. Cumberland, Maha El-Sayed, Alan J. Fujii, Scott D Manske, Elias A. Shaheen
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Publication number: 20090165228Abstract: A cleaning implement with a handle and a removable cleaning pad can be used to effectively clean surfaces. The cleaning pad is impregnated with an acidic cleaning composition. The cleaning pad may be dry to the touch. The cleaning implement may be a manual tool or a motorized tool. Examples of suitable cleaning implements include a hard surface floor mop, a carpet mop, an auto cleaning device, a toilet cleaning device, a bathroom cleaning device, and a shower cleaning device.Type: ApplicationFiled: December 5, 2008Publication date: July 2, 2009Inventors: Andrew Kilkenny, Maha El-Sayed, Lafayette D. Foland, Shona L. Nelson, Cheryl Rodriguez, David R. Scheuing
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Publication number: 20090148342Abstract: This invention generally relates to compositions and method of producing diluted hypohalous acid and hypohalous acid vapor. These compositions can be used to treat allergen containing surfaces, hard surfaces, food contact surfaces, hospital surfaces, food surfaces, kitchen surfaces, bathroom surfaces, human surfaces, animal surfaces, children's items, outdoor surfaces, soft surfaces, and medical instruments. These compositions can be converted to solid particulate or granular compositions. These compositions can be put into a variety of containers which preserve the stability. These compositions can be used to treat allergens and molds and as part of a mold detection system. These compositions can be dispersed into the air to enable microbiological control.Type: ApplicationFiled: October 29, 2007Publication date: June 11, 2009Inventors: Steven E. Bromberg, Bruce K. Bitowft, Elizabeth Crane, Maha El-Sayed, Daniel A. Huitt, Andreas Nguyen, Ricardo Ruiz de Gopegui, Doris S. Shieh, William L. Smith, Julie Timberman, Aram Garabedian, Lachelle Arnt, Elias A. Shaheen, Steven Bromberg, Vicki Friedman, Jennifer Fung, Jennifer C. Julian, Kenneth Vieira, Julie Wiesman, Timothy Kennedy, Chih Chiang, Kenneth L. Vieira, Maria G. Ochomogo, Scott Cumberland, Daniel Aaron Huitt, Diane Mellett, Nikhil Dani, Maha Y. El-Sayed, Lafayette D. Foland, Jorge Robles, Elias A. Shaheen
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Publication number: 20090075250Abstract: Provided is sampling and testing device for the detection of specific molds, allergens, viruses, bacteria, fungi, and other protein containing substances. Embodiments of the device include a sampling member slideably engaged with a base that contains a lateral flow strip adapted to detect specific analytes of interest. The sampling member defines a solvent reservoir that stores an elution solvent in a fluid-tight manner before the device is used to sample and test environmental surfaces. During slideable withdrawal of the sampling member from the base, the elution solvent stored in the reservoir is automatically released to a wick assembly of the sampling member. The wick assembly includes a wick adapted to receive, distribute, and retain the elution solvent. After a user samples an environmental surface for an analyte of interest with the elution solvent wetted wick, the sampling member is returned to the base where the wick contacts the lateral flow strip contained in the base.Type: ApplicationFiled: November 20, 2008Publication date: March 19, 2009Applicant: The Clorox CompanyInventors: Brendi M. Cumberland, Maha El-Sayed, Alan J. Fujii, Scott D. Manske, Elias A. Shaheen