Patents by Inventor Mahadeo Bhaskar Tryambake

Mahadeo Bhaskar Tryambake has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted bicyclic heterocyclic compounds as PRMT5 inhibitors
    Patent number: 11952380
    Abstract: The invention relates to substituted bicyclic heterocyclic compounds of formula (I), pharmaceutically acceptable salts thereof and pharmaceutical compositions for treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme. The invention also relates to methods of treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme.
    Type: Grant
    Filed: May 6, 2022
    Date of Patent: April 9, 2024
    Assignee: LUPIN LIMITED
    Inventors: Prathap Sreedharan Nair, Ganesh Bhausaheb Gudade, Sachin Sethi, Dipak Raychand Lagad, Chetan Sanjay Pawar, Mahadeo Bhaskar Tryambake, Chaitanya Prabhakar Kulkarni, Anil Kashiram Hajare, Balasaheb Arjun Gore, Sanjeev Anant Kulkarni, Milind Dattatraya Sindkhedkar, Venkata P. Palle, Rajender Kumar Kamboj
  • PRMT5 INHIBITORS
    Publication number: 20220315589
    Abstract: The invention relates to substituted nucleoside analogues of formula (I), pharmaceutically acceptable salts thereof and pharmaceutical compositions for treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme. The invention also relates to methods of treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme.
    Type: Application
    Filed: June 9, 2020
    Publication date: October 6, 2022
    Inventors: Prathap Sreedharan Nair, Ganesh Bhausaheb Gudade, Mahadeo Bhaskar Tryambake, Chetan Sanjay Pawar, Dipak Raychand Lagad, Chaitanya Prabhakar Kulkarni, Milind Dattatraya Sindkhedkar, Venkata P. Palle, Rajender Kumar Kamboj
  • Substituted bicyclic heterocyclic compounds as PRMT5 inhibitors
    Patent number: 11459330
    Abstract: The invention relates to substituted bicyclic heterocyclic compounds of formula (I), pharmaceutically acceptable salts thereof and pharmaceutical compositions for treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme. The invention also relates to methods of treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme.
    Type: Grant
    Filed: December 13, 2018
    Date of Patent: October 4, 2022
    Assignee: LUPIN LIMITED
    Inventors: Prathap Sreedharan Nair, Ganesh Bhausaheb Gudade, Sachin Sethi, Dipak Raychand Lagad, Chetan Sanjay Pawar, Mahadeo Bhaskar Tryambake, Chaitanya Prabhakar Kulkarni, Anil Kashiram Hajare, Balasaheb Arjun Gore, Sanjeev Anant Kulkarni, Milind Dattatraya Sindkhedkar, Venkata P. Palle, Rajender Kumar Kamboj
  • SUBSTITUTED BICYCLIC HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS
    Publication number: 20220267339
    Abstract: The invention relates to substituted bicyclic heterocyclic compounds of formula (I), pharmaceutically acceptable salts thereof and pharmaceutical compositions for treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme. The invention also relates to methods of treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme.
    Type: Application
    Filed: May 6, 2022
    Publication date: August 25, 2022
    Applicant: LUPIN LIMITED
    Inventors: Prathap Sreedharan Nair, Ganesh Bhausaheb Gudade, Sachin Sethi, Dipak Raychand Lagad, Chetan Sanjay Pawar, Mahadeo Bhaskar Tryambake, Chaitanya Prabhakar Kulkarni, Anil Kashiram Hajare, Balasaheb Arjun Gore, Sanjeev Anant Kulkarni, Milind Dattatraya Sindkhedkar, Venkata P. Palle, Rajender Kumar Kamboj
  • SUBSTITUTED BICYCLIC HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS
    Publication number: 20210163486
    Abstract: The invention relates to substituted bicyclic heterocyclic compounds of formula (I), pharmaceutically acceptable salts thereof and pharmaceutical compositions for treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme. The invention also relates to methods of treating diseases, disorders or conditions associated with the overexpression of PRMT5 enzyme.
    Type: Application
    Filed: December 13, 2018
    Publication date: June 3, 2021
    Applicant: LUPIN LIMITED
    Inventors: Prathap Sreedharan Nair, Ganesh Bhausaheb Gudade, Sachin Sethi, Dipak Raychand Lagad, Chetan Sanjay Pawar, Mahadeo Bhaskar Tryambake, Chaitanya Prabhakar Kulkarni, Anil Kashiram Hajare, Balasaheb Arjun Gore, Sanjeev Anant Kulkarni, Milind Dattatraya Sindkhedkar, Venkata P. Palle, Rajender Kumar Kamboj
  • ARYLALKYLAMINE COMPOUNDS AS CALCIUM SENSING RECEPTOR MODULATORS
    Publication number: 20170137371
    Abstract: The present invention provides arylalkylamine compounds as calcium sensing receptor modulators (CaSR). In particular, the compounds described herein are useful for treating, managing, and/or lessening the severity of diseases, disorders, syndromes and/or conditions associated with the modulation of calcium sensing receptors (CaSR). The invention also provides herein the pharmaceutical compositions thereof, and methods for treating, managing, and/or lessening the severity of diseases, disorders, syndromes and/or conditions associated with the modulation of CaSR. The invention also relates to process for the preparation of the compounds of the invention.
    Type: Application
    Filed: January 31, 2017
    Publication date: May 18, 2017
    Inventors: Manojkumar Ramprasad Shukla, Vinod Dinkar Chaudhari, Ankush Gangaram Sarde, Ramesh Dattatraya Phadtare, Mahadeo Bhaskar Tryambake, Dronamraju Prameela, Sanjeev Anant Kulkarni, Rajender Kumar Kamboj, Venkata P. Palle
  • Arylalkylamine compounds as calcium sensing receptor modulators
    Patent number: 9598371
    Abstract: The present invention provides arylalkylamine compounds as calcium sensing receptor modulators (CaSR). In particular, the compounds described herein are useful for treating, managing, and/or lessening the severity of diseases, disorders, syndromes and/or conditions associated with the modulation of calcium sensing receptors (CaSR). The invention also provides herein the pharmaceutical compositions thereof, and methods for treating, managing, and/or lessening the severity of diseases, disorders, syndromes and/or conditions associated with the modulation of CaSR. The invention also relates to process for the preparation of the compounds of the invention.
    Type: Grant
    Filed: November 25, 2015
    Date of Patent: March 21, 2017
    Assignee: LUPIN ATLANTIS HOLDINGS SA
    Inventors: Manojkumar Ramprasad Shukla, Vinod Dinkar Chaudhari, Ankush Gangaram Sarde, Ramesh Dattatraya Phadtare, Mahadeo Bhaskar Tryambake, Dronamraju Prameela, Sanjeev Kulkarni, Rajender Kumar Kamboj, Venkata P. Palle
  • Substituted naphthalene compounds as calcium sensing receptor modulators
    Patent number: 9493396
    Abstract: The invention relates to naphthalene compounds of Formula (I) and their pharmaceutically acceptable salts, wherein the substituents are as described herein, and their use in medicine for the treatment of diseases, disorders associated with the modulation of calcium sensing receptor modulators (Ca SR). The invention also relates to pharmaceutical compositions containing such compounds in treating diseases disorders associated with calcium sensing receptor modulators (Ca SR) channel modulators.
    Type: Grant
    Filed: August 26, 2014
    Date of Patent: November 15, 2016
    Assignee: LUPIN ATLANTIS HOLDINGS SA
    Inventors: Prathap Sreedharan Nair, Ganesh Bhausaheb Gudade, Mahadeo Bhaskar Tryambake, Chetan Sanjay Pawar, Sanjeev Anant Kulkarni, Venkata P. Palle, Rajender Kumar Kamboj
  • Benzo [B] [1,4] oxazin derivatives as calcium sensing receptor modulators
    Patent number: 9464063
    Abstract: Compounds of Formula (I) along with processes for their preparation that are useful for treating, managing and/or lessening the diseases, disorders, syndromes or conditions associated with the modulation of calcium sensing (CaSR) receptors. Methods of treating, managing and/or lessening the diseases, disorders, syndromes or conditions associated with the modulation of calcium sensing (CaSR) receptors of Formula (I).
    Type: Grant
    Filed: March 16, 2012
    Date of Patent: October 11, 2016
    Assignee: LUPIN ATLANTIS HOLDINGS SA
    Inventors: Manojkumar Ramprasad Shukla, Sarde Gangaram Ankush, Pachpute Dilip Vipul, Majid Bashir Sayyed, Mahadeo Bhaskar Tryambake, Chetan Sanjay Pawar, Ganesh Navinchandra Gote, Sanjeev Anant Kulkarni, Venkata P. Palle, Rajender Kumar Kamboj
  • SUBSTITUTED NAPHTHALENE COMPOUNDS AS CALCIUM SENSING RECEPTOR MODULATORS
    Publication number: 20160214924
    Abstract: The invention relates to naphthalene compounds of Formula (I) and their pharmaceutically acceptable salts, wherein the substituents are as described herein, and their use in medicine for the treatment of diseases, disorders associated with the modulation of calcium sensing receptor modulators (Ca SR). The invention also relates to pharmaceutical compositions containing such compounds in treating diseases disorders associated with calcium sensing receptor modulators (Ca SR) channel modulators.
    Type: Application
    Filed: August 26, 2014
    Publication date: July 28, 2016
    Inventors: Prathap Sreedharan NAIR, Ganesh Bhausaheb GUDADE, Mahadeo Bhaskar TRYAMBAKE, Chetan Sanjay PAWAR, Sanjeev Anant KULKARNI, Venkata P. PALLE, Rajender Kumar KAMBOJ
  • ARYLALKYLAMINE COMPOUNDS AS CALCIUM SENSING RECEPTOR MODULATORS
    Publication number: 20160075655
    Abstract: The present invention provides arylalkylamine compounds as calcium sensing receptor modulators (CaSR). In particular, the compounds described herein are useful for treating, managing, and/or lessening the severity of diseases, disorders, syndromes and/or conditions associated with the modulation of calcium sensing receptors (CaSR). The invention also provides herein the pharmaceutical compositions thereof, and methods for treating, managing, and/or lessening the severity of diseases, disorders, syndromes and/or conditions associated with the modulation of CaSR. The invention also relates to process for the preparation of the compounds of the invention.
    Type: Application
    Filed: November 25, 2015
    Publication date: March 17, 2016
    Inventors: Manojkumar Ramprasad Shukla, Vinod Dinkar Chaudhari, Ankush Gangaram Sarde, Ramesh Dattatraya Phadtare, Mahadeo Bhaskar Tryambake, Dronamraju Prameela, Sanjeev Kulkarni, Rajender Kumar Kamboj, Venkata P. Palle
  • Arylalkylamine compounds as calcium sensing receptor modulators
    Patent number: 9227919
    Abstract: The present invention provides arylalkylamine compounds as calcium sensing receptor modulators (CaSR). In particular, the compounds described herein are useful for treating, managing, and/or lessening the severity of diseases, disorders, syndromes and/or conditions associated with the modulation of calcium sensing receptors (CaSR). The invention also provides herein the pharmaceutical compositions thereof, and methods for treating, managing, and/or lessening the severity of diseases, disorders, syndromes and/or conditions associated with the modulation of CaSR. The invention also relates to process for the preparation of the compounds of the invention.
    Type: Grant
    Filed: August 23, 2013
    Date of Patent: January 5, 2016
    Assignee: Lupin Limited
    Inventors: Manojkumar Ramprasad Shukla, Vinod Dinkar Chaudhari, Ankush Gangaram Sarde, Ramesh Dattatraya Phadtare, Mahadeo Bhaskar Tryambake, Dronamraju Prameela, Sanjeev Anant Kulkarni, Rajender Kumar Kamboj, Venkata P. Palle
  • ARYLALKYLAMINE COMPOUNDS AS CALCIUM SENSING RECEPTOR MODULATORS
    Publication number: 20150239827
    Abstract: The present invention provides arylalkylamine compounds as calcium sensing receptor modulators (CaSR). In particular, the compounds described herein are useful for treating, managing, and/or lessening the severity of diseases, disorders, syndromes and/or conditions associated with the modulation of calcium sensing receptors (CaSR). The invention also provides herein the pharmaceutical compositions thereof, and methods for treating, managing, and/or lessening the severity of diseases, disorders, syndromes and/or conditions associated with the modulation of CaSR. The invention also relates to process for the preparation of the compounds of the invention.
    Type: Application
    Filed: August 23, 2013
    Publication date: August 27, 2015
    Inventors: Manojkumar Ramprasad Shukla, Vinod Dinkar Chaudhari, Ankush Gangaram Sarde, Ramesh Dattatraya Phadtare, Mahadeo Bhaskar Tryambake, Dronamraju Prameela, Sanjeev Anant Kulkarni, Rajender Kumar Kamboj, Venkata P. Palle
  • BENZO [B] [1,4] OXAZIN DERIVATIVES AS CALCIUM SENSING RECEPTOR MODULATORS
    Publication number: 20140018358
    Abstract: Compounds of Formula (I) along with processes for their preparation that are useful for treating, managing and/or lessening the diseases, disorders, syndromes or conditions associated with the modulation of calcium sensing (CaSR) receptors. Methods of treating, managing and/or lessening the diseases, disorders, syndromes or conditions associated with the modulation of calcium sensing (CaSR) receptors of Formula (I).
    Type: Application
    Filed: March 16, 2012
    Publication date: January 16, 2014
    Applicant: LUPIN LIMITED
    Inventors: Manojkumar Ramprasad Shukla, Sarde Gangaram Ankush, Pachpute Dilip Vipul, Majid Bashir Sayyed, Mahadeo Bhaskar Tryambake, Chetan Sanjay Pawar, Ganesh Navinchandra Gote, Sanjeev Anant Kulkarni, Venkata P. Palle, Rajender Kumar Kamboj