Abstract: Described embodiments include a final dosage form for administering a medicament to an animal, an article of manufacture, and method. A described final dosage form includes a dosage portion having a medicament and a release element in a first medicament-release state. The medicament has a first bioavailability to the animal. The release element is modifiable ex vivo to a second medicament-release state by an exposure to a stimulus, wherein the medicament has a second bioavailability to the animal. The final dosage form includes another dosage portion having another medicament and another release element in another first medicament-release state. In the another first medicament-release state, the another medicament has another first bioavailability to the animal. The another release element is modifiable ex vivo to another second medicament-release state by an exposure to another stimulus, wherein the another medicament has another second bioavailability to the animal.

Abstract: A multilayer material is described herein that includes a flexible inner layer and a flexible outer layer configured to enclose at least one signaling layer, the at least one signaling layer including at least one chemical compound. The multilayer material including the chemical compound within the at least one signaling layer is configured to release a gas-phase chemical compound to signal to a detector indicating a breach of the multilayer material. A multilayer material, a system, an article of clothing, or a method is described herein.

Abstract: Computer-based systems and computer-implemented methods are described for monitoring medication events for an individual. Computer-based systems include systems for monitoring medication events relating to an individual, including: circuitry for analyzing data for an identifier of a first medication event for an individual; circuitry for analyzing the data for at least one attribute of an individual; circuitry for analyzing the data for at least one attribute relating to a medication during the first medication event; circuitry for analyzing the data for at least one feature of visual information and at least one feature of non-visual information relating to the individual during the first medication event; circuitry for analyzing the received data for a time associated with the first medication event; circuitry for determining a compliance likelihood for the first medication event based on the analyses of the received data; and circuitry for indicating the determined compliance likelihood.

Abstract: Described embodiments include a final dosage form for administering a medicament to an animal, an article of manufacture, and method. A described final dosage form includes a dosage portion having a medicament and a release element in a first medicament-release state. The medicament has a first bioavailability to the animal. The release element is modifiable ex vivo to a second medicament-release state by an exposure to a stimulus, wherein the medicament has a second bioavailability to the animal. The final dosage form includes another dosage portion having another medicament and another release element in another first medicament-release state. In the another first medicament-release state, the another medicament has another first bioavailability to the animal. The another release element is modifiable ex vivo to another second medicament-release state by an exposure to another stimulus, wherein the another medicament has another second bioavailability to the animal.

Abstract: Devices, methods, and systems are described for administration to at least one biological tissue of at least one device including at least one altered microorganism. In an embodiment, the altered microorganism includes at least one nucleic acid construct encoding at least one therapeutic agent.

Abstract: A multilayer material is described herein that includes at least one signaling layer configured to propagate at least one electromagnetic signal; and a flexible layer configured to enclose the at least one signaling layer, wherein the flexible layer is substantially impermeable to an environment and to the at least one electromagnetic signal. The multilayer material including the at least one signaling layer is configured to transmit a change in the at least one electromagnetic signal upon exposure of the signaling layer to the environment. A system, an article of clothing, or a method is described herein.

Abstract: Devices, methods, and systems are described for administration to at least one biological tissue of at least one device including at least one altered microorganism. In an embodiment, the altered microorganism includes at least one nucleic acid construct encoding at least one therapeutic agent.

Abstract: Computer-based systems and computer-implemented methods are described for monitoring medication events for an individual. Computer-based systems include systems for monitoring medication events relating to an individual, including: circuitry for analyzing data for an identifier of a first medication event for an individual; circuitry for analyzing the data for at least one attribute of an individual; circuitry for analyzing the data for at least one attribute relating to a medication during the first medication event; circuitry for analyzing the data for at least one feature of visual information and at least one feature of non-visual information relating to the individual during the first medication event; circuitry for analyzing the received data for a time associated with the first medication event; circuitry for determining a compliance likelihood for the first medication event based on the analyses of the received data; and circuitry for indicating the determined compliance likelihood.

Abstract: Computer-based systems and computer-implemented methods are described for monitoring medication events for an individual. Computer-based systems include systems for monitoring medication events relating to an individual, including: circuitry for analyzing data for an identifier of a first medication event for an individual; circuitry for analyzing the data for at least one attribute of an individual; circuitry for analyzing the data for at least one attribute relating to a medication during the first medication event; circuitry for analyzing the data for at least one feature of visual information and at least one feature of non-visual information relating to the individual during the first medication event; circuitry for analyzing the received data for a time associated with the first medication event; circuitry for determining a compliance likelihood for the first medication event based on the analyses of the received data; and circuitry for indicating the determined compliance likelihood.

Abstract: Computer-based systems and computer-implemented methods are described for monitoring medication events for an individual. Computer-based systems include systems for monitoring medication events relating to an individual, including: circuitry for analyzing data for an identifier of a first medication event for an individual; circuitry for analyzing the data for at least one attribute of an individual; circuitry for analyzing the data for at least one attribute relating to a medication during the first medication event; circuitry for analyzing the data for at least one feature of visual information and at least one feature of non-visual information relating to the individual during the first medication event; circuitry for analyzing the received data for a time associated with the first medication event; circuitry for determining a compliance likelihood for the first medication event based on the analyses of the received data; and circuitry for indicating the determined compliance likelihood.

Abstract: Wearable injection guides and manufacture and use thereof are described, which include: a rigid needle-penetrable material having an inner surface and an outer surface, the inner surface having form-fitting contours substantially conforming to a topography of a body region of an individual and the outer surface including one or more fiducials indication of at least one treatment parameter.

Abstract: Systems and methods for wearable injection guides are described, which include: acquiring one or more digital images of a body region of an individual with at least one image capture device; creating a digitally rendered model of a wearable injection guide from the one or more digital images of the body region of the individual; adding one or more digitally rendered fiducials indicative of at least one treatment parameter to the digitally rendered model of the wearable injection guide; and forming the wearable injection guide from the digitally rendered model of the wearable injection guide, the formed wearable injection guide including one or more fiducials corresponding to the one or more digitally rendered fiducials on the digitally rendered model of the wearable injection guide.

Abstract: Wearable injection guides and manufacture and use thereof are described, which include: a rigid material formed to substantially conform in shape to a topography of a body region of an individual, the rigid material substantially impenetrable to an injection needle, and the rigid material including one or more injection needle access regions arranged in a treatment pattern.

Abstract: A multilayer material is described herein that includes a flexible inner layer and a flexible outer layer configured to enclose at least one signaling layer, the at least one signaling layer including at least one chemical compound. The multilayer material including the chemical compound within the at least one signaling layer is configured to release a gas-phase chemical compound to signal to a detector indicating a breach of the multilayer material. A multilayer material, a system, an article of clothing, or a method is described herein.

Abstract: Embodiments disclosed herein relate to methods, devices, and computer systems thereof for automated data collection from a subject. In certain embodiments, one or more characteristics of a subject are sensed, and the subject is given a queue status indicator based on a comparison of the subject's one or more sensed characteristics with corresponding sensed characteristics from other subjects. In one embodiment, the subject is a healthcare worker and the system, methods, and devices are utilized to evaluate the overall health of the worker as part of the check-in process for work.

Abstract: Embodiments disclosed herein relate to methods, devices, and computer systems thereof for automated data collection from a subject. In certain embodiments, one or more characteristics of a subject are sensed, and the subject is given a queue status indicator based on a comparison of the subject's one or more sensed characteristics with corresponding sensed characteristics from other subjects. In one embodiment, the subject is a healthcare worker and the system, methods, and devices are utilized to evaluate the overall health of the worker as part of the check-in process for work.

Abstract: Embodiments disclosed herein are directed to fluid spraying apparatuses, and related systems and methods. The disclosed fluid spraying apparatuses may be used, for example, to spray a medically suitable fluid on a target region of a living subject such as for treating or removing tissue. In an embodiment, a fluid spraying apparatus includes a target designation unit having a target sensor configured to sense a target region of a living subject, a spray mechanism, and a controller. The spray mechanism includes at least one reservoir configured to hold fluid, and a spraying device operably coupled to the at least one reservoir, the spraying device configured to spray the fluid in the at least one reservoir onto the target region. The controller includes control electrical circuitry operably coupled to the spray mechanism and the target designation unit, and configured to control the spray mechanism responsive to the target sensor sensing the target region.

Abstract: Embodiments disclosed herein relate to methods, devices, and computer systems thereof for automated data collection from a subject. In certain embodiments, one or more characteristics of a subject are sensed, and the subject is given a queue status indicator based on a comparison of the subject's one or more sensed characteristics with corresponding sensed characteristics from other subjects. In one embodiment, the subject is a healthcare worker and the system, methods, and devices are utilized to evaluate the overall health of the worker as part of the check-in process for work.

Abstract: Embodiments disclosed herein are directed to fluid spraying apparatuses, and related systems and methods. The disclosed fluid spraying apparatuses may be used, for example, to spray a medically suitable fluid on a target region of a subject, such as for treating or removing tissue of the subject. In an embodiment, a fluid spraying apparatus includes a spray mechanism including at least one reservoir, and a spraying device operably coupled to the at least one reservoir which has an adjustable spray nozzle. The fluid spraying apparatus includes a distance sensor configured to sense information at least related to a distance to a target region of a subject and output one or more signals encoding the information, and control electrical circuitry operably coupled to the spray mechanism and the distance sensor. The control electrical circuitry is configured to activate the spray mechanism responsive to receiving the one or more signals.

Abstract: Embodiments disclosed herein include air-treatment mask systems having at least one controllable air-treatment device that is controlled responsive to one or more signals from at least one pollutant sensor, and related methods of operation and air-treatment masks. In an embodiment, an air-treatment mask system includes a wearable air-treatment mask having a mask body including a face-securing member, and at least one controllable air-treatment device supported by the mask body. The air-treatment device is configured to treat incoming air. The system includes at least one pollutant sensor configured to sense ambient air for a presence of at least one pollutant and output one or more signals responsive to the sensing. The system includes control electrical circuitry operably coupled to the air-treatment device and the pollutant sensor and configured to control operation of the controllable air-treatment device responsive to receiving the signal(s) from the pollutant sensor.