Patents by Inventor Maharukh T. Rustomjee

Maharukh T. Rustomjee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9801821
    Abstract: The present invention relates to stable solid formulations of vitamin D3 and to processes for preparation of the same. The present invention provides stabilized compositions comprising vitamin D3 at least one lipophilic dispersant, one or more antioxidants, at least one adsorbent and one or more pharmaceutically acceptable excipients and further coated with a barrier coating.
    Type: Grant
    Filed: March 27, 2014
    Date of Patent: October 31, 2017
    Assignee: PSM Healthcare Limited
    Inventors: Anilkumar S. Gandhi, Pratibha S. Pilgaonkar, Maharukh T. Rustomjee
  • Patent number: 9629915
    Abstract: The novel sustained release dosage form comprising an active agent and a combination of a non-swelling pH dependent release retardant and a non swelling pH independent release retardant polymer which provides pH-independent drug release for a considerable period of time after administration.
    Type: Grant
    Filed: December 5, 2014
    Date of Patent: April 25, 2017
    Assignee: Rubicon Research Private Limited
    Inventors: Pratibha S Pilgaonkar, Maharukh T Rustomjee, Anilkumar S Gandhi, Paras R Jain, Atul A Kelkar
  • Patent number: 9295643
    Abstract: A solvent free process of obtaining an insoluble fiber rich fraction from Trigonella Foenum-graceum seeds is disclosed. The multifunctional fiber rich fraction (FRF) and highly purified FRF are useful as excipients for pharmaceutical dosage forms for various routes of administration. These excipients can be used as binder, disintegrant, filler, dispersing agent, coating agent, film forming agent, thickener and the like, for preparation of variety of dosage forms. FRF and highly purified FRF can also be used in a controlled release, targeted release and other specialized delivery systems, as well as in food and cosmetics formulation.
    Type: Grant
    Filed: September 21, 2004
    Date of Patent: March 29, 2016
    Inventors: Pratibha S. Pilgaonkar, Maharukh T. Rustomjee, Anilkumar S. Gandhi, Vinderjit Sarjit Bhumra
  • Publication number: 20160030356
    Abstract: The present invention relates to stable solid formulations of vitamin D3 and to processes for preparation of the same. The present invention provides stabilized compositions comprising vitamin D3 at least one lipophilic dispersant, one or more antioxidants, at least one adsorbent and one or more pharmaceutically acceptable excipients and further coated with a barrier coating.
    Type: Application
    Filed: March 27, 2014
    Publication date: February 4, 2016
    Inventors: Anilkumar S. Gandhi, Pratibha Pilgaonkar, Maharukh T. Rustomjee
  • Publication number: 20150150991
    Abstract: The novel sustained release dosage form comprising an active agent and a combination of a non-swelling pH dependent release retardant and a non swelling pH independent release retardant polymer which provides pH-independent drug release for a considerable period of time after administration.
    Type: Application
    Filed: December 5, 2014
    Publication date: June 4, 2015
    Inventors: Pratibha S. Pilgaonkar, Maharukh T. Rustomjee, Anilkumar S. Gandhi, Paras R. Jain, Atul A. Kelkar
  • Publication number: 20150079136
    Abstract: The present invention relates to controlled release pharmaceutical formulations of direct thrombin inhibitors and processes for preparing such compositions. Particularly the present invention relates to oral controlled release pharmaceutical compositions comprising dabigatran etexilate or pharmaceutically acceptable salts thereof.
    Type: Application
    Filed: April 10, 2013
    Publication date: March 19, 2015
    Inventors: Pratibha S. Pilgaonkar, Maharukh T. Rustomjee, Anilkumar S. Gandhi
  • Publication number: 20150030680
    Abstract: Compositions comprising a mixture of at least two types of particles wherein a) the first type of particles comprise dabigatran etexilate in the form of the free base or in the form of pharmaceutically acceptable salts, polymorphs, solvates or hydrates thereof; and b) the second type of particles comprise at least one pharmaceutically acceptable organic acid, use of said compositions in the reduction of the risk of stroke and systemic embolism in patients with non-valvular atrial fibrillation and/or in the prevention of venous thromboembolic events in adult patients who have undergone elective total hip replacement surgery or total knee replacement surgery and processes for the preparation of said compositions.
    Type: Application
    Filed: February 21, 2013
    Publication date: January 29, 2015
    Inventors: Pratibha S. Pilgaonkar, Maharukh T. Rustomjee, Anilkumar S. Gandhi
  • Patent number: 8920837
    Abstract: The novel sustained release dosage form comprising an active agent and a combination of a non-swelling pH dependent release retardant and a non swelling pH independent release retardant polymer which provides pH-independent drug release for a considerable period of time after administration.
    Type: Grant
    Filed: July 3, 2006
    Date of Patent: December 30, 2014
    Assignee: Rubicon Research Private Limited
    Inventors: Pratibha S. Pilgaonkar, Maharukh T. Rustomjee, Anilkumar S. Gandhi, Paras R. Jain, Atul A. Kelkar
  • Publication number: 20140314847
    Abstract: The present invention provides a controlled release oral pharmaceutical composition having a therapeutically effective amount of one or more pharmacologically active agent having low bioavailability; one or more solubilizers; one or more biocompatible swelling agents; and a swelling enhancer. The swelling agent, in combination with swelling enhancer, swells in the presence of water in gastric fluid such that the size of the dosage form is sufficiently increased to provide retention of the dosage form in the stomach of a patient, which gradually erodes within the gastrointestinal tract over a prolonged time period.
    Type: Application
    Filed: July 2, 2014
    Publication date: October 23, 2014
    Inventors: Pratibha S. PILGAONKAR, Maharukh T. RUSTOMJEE, Anilkumar S. GANDHI, Pradnya M. BAGDE
  • Publication number: 20100119607
    Abstract: The present invention relates to the method of increasing the bioavailability of Angiotensin II Receptor Blockers (ARBs) by preparing a composition of an ARB with at least one solubility enhancing agent. The invention is particularly focused to provide a novel or modified dissolution profile where the release of ARB in the GI tract is independent of physiological pH conditions.
    Type: Application
    Filed: September 10, 2009
    Publication date: May 13, 2010
    Inventors: Nagesh R. PALEPU, Pratibha S. PILGAONKAR, Maharukh T. RUSTOMJEE, Anilkumar S. GANDHI, Paras R. JAIN
  • Publication number: 20090208576
    Abstract: The present invention describes a directly compressible composite prepared by co-processing a water-soluble excipient and calcium silicate. The present invention further describes the incorporation of the co-processed composite into a tablet formulation. The orally disintegrating tablets are of optimal mechanical strength and disintegrate within 60 seconds in the oral cavity.
    Type: Application
    Filed: March 30, 2007
    Publication date: August 20, 2009
    Inventors: Anilkumar S. Gandhi, Pradnya Bagde, Hetal N. Morvekar, Pratibha S. Pilgaonkar, Maharukh T. Rustomjee
  • Publication number: 20090123543
    Abstract: A novel solid oral dosage form comprising a therapeutically effective amount of hydrophobic pharmacological active ingredient and at least one particle separating agent preferably selected from a class of wetting agents, prepared without or with minimum amount of a disintegrating agent. The hydrophobic pharmacological active ingredient active ingredient belongs to the class of angiotensin receptor blocking agents preferably is valsartan optionally in combination with hydrochlorothiazide. The active ingredient may also be a class of 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase inhibitors preferably atorvastatin. The ratio of hydrophobic active ingredient to particle separating agent is about 20:1 to about 1:20. The process for the preparation of the novel solid oral dosage form comprises treating a hydrophobic active ingredient with at least one particle separating agent, and incorporating the treated hydrophobic active ingredient into a solid dosage form.
    Type: Application
    Filed: January 2, 2007
    Publication date: May 14, 2009
    Applicant: Rubicon Research Private Limited
    Inventors: Pratibha S. Pilgaonkar, Maharukh T. Rustomjee, Anilkumar S. Gandhi, Paras R. Jain
  • Publication number: 20090053310
    Abstract: The novel sustained release dosage form comprising an active agent and a combination of a non-swelling pH dependent release retardant and a non swelling pH independent release retardant polymer which provides pH-independent drug release for a considerable period of time after administration.
    Type: Application
    Filed: July 3, 2006
    Publication date: February 26, 2009
    Inventors: Pratibha S. Pilgaonkar, Maharukh T. Rustomjee, Anilkumar S. Gandhi, Paras R. Jain, Atul A. Kelkar
  • Publication number: 20080248107
    Abstract: The present invention provides a controlled release formulation comprising an therapeutically effective amount of pharmacologically active substance having high water solubility, at least one non-polymeric release retardant, and at least one pH independent non-swelling release retarding polymer. The said dosage form provides controlled release of the active agent with reduced initial burst release.
    Type: Application
    Filed: August 24, 2006
    Publication date: October 9, 2008
    Applicant: Rubicon Research Pvt. Ltd.
    Inventors: Pratibha S. Pilgaonkar, Maharukh T. Rustomjee, Anikumar S. Gandhi, Atul A. Kelkar, Pradnya Bagde
  • Publication number: 20040228932
    Abstract: The invention relates to a multifunctional fiber rich fraction (FRF) useful as an excipient for pharmaceutical dosage forms for various routes of administration. This excipient can be used as binder, disintegrant, filler, dispersing agent, coating agent, film forming agent, thickener etc for preparation of variety of dosage forms. This FRF can also be used in a controlled release, targeted release and other specialized delivery systems, as well as in food and cosmetics formulation.
    Type: Application
    Filed: May 12, 2003
    Publication date: November 18, 2004
    Inventors: Pratibha S. Pilgaonkar, Maharukh T. Rustomjee, Anilkumar S. Gandhi, Vinderjit S. Bhumra