Patents by Inventor Mahavir Singh Khanna

Mahavir Singh Khanna has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of ibrutinib
    Patent number: 10196397
    Abstract: The present invention provides processes for the preparation of ibrutinib, intermediate compounds of Formula VI and Formula VIII, and salts thereof. The processes of the present invention are commercially viable, cost-effective, environmentally friendly, and make use of inexpensive, non-hazardous, safe chemicals that are easy to handle.
    Type: Grant
    Filed: November 18, 2015
    Date of Patent: February 5, 2019
    Assignee: Sun Pharmaceutical Industries Limited
    Inventors: Kapil Sharma, Bhavin Prabhudas Thanki, Mahavir Singh Khanna, Mohan Prasad
  • Stable amorphous ticagrelor and a process for its preparation
    Patent number: 10017515
    Abstract: The present invention relates to a stable amorphous ticagrelor and a process for its preparation.
    Type: Grant
    Filed: August 11, 2015
    Date of Patent: July 10, 2018
    Assignee: Sun Pharmaceutical Industries Limited
    Inventors: Nagaraju Gottumukkala, Anil Saini, Ram Thaimattam, Mahavir Singh Khanna, Mohan Prasad
  • A PROCESS FOR THE PREPARATION OF IBRUTINIB
    Publication number: 20170320879
    Abstract: The present invention provides processes for the preparation of ibrutinib, intermediate compounds of Formula VI and Formula VIII, and salts thereof. The processes of the present invention are commercially viable, cost-effective, environmentally friendly, and make use of inexpensive, non-hazardous, safe chemicals that are easy to handle.
    Type: Application
    Filed: November 18, 2015
    Publication date: November 9, 2017
    Inventors: Kapil SHARMA, Bhavin Prabhudas THANKI, Mahavir Singh KHANNA, Mohan PRASAD
  • STABLE AMORPHOUS TICAGRELOR AND A PROCESS FOR ITS PREPARATION
    Publication number: 20170253599
    Abstract: The present invention relates to a stable amorphous ticagrelor and a process for its preparation.
    Type: Application
    Filed: August 11, 2015
    Publication date: September 7, 2017
    Inventors: Nagaraju GOTTUMUKKALA, Anil SAINI, Ram THAIMATTAM, Mahavir Singh KHANNA, Mohan PRASAD
  • Pure crystalline Form II of L-malic acid salt of sunitinib and processes for its preparation
    Patent number: 9604968
    Abstract: The present invention relates to pure crystalline Form II of an L-malic acid salt of sunitinib and a process for its preparation. The invention further provides crystalline Form II of an L-malic acid salt of sunitinib having a purity of at least 97.0%. The invention also provides crystalline Form II of an L-malic acid salt of sunitinib substantially free of an anti-oxidant. The invention also provides crystalline Form II of L-malic acid salt of sunitinib which remains chemically pure on storage at 25° C.±2° C. and 40° C.±2° C. at a relative humidity of 60%±5% and 75%±5%, respectively, for at least 1 month.
    Type: Grant
    Filed: January 6, 2014
    Date of Patent: March 28, 2017
    Assignee: Sun Pharmaceutical Industries Limited
    Inventors: Hari Babu Matta, Mahavir Singh Khanna, Mohan Prasad
  • Ascorbic acid salt of sunitinib
    Patent number: 9278955
    Abstract: The present invention relates to an ascorbic acid salt of sunitinib and a process for its preparation. The present invention further provides a crystalline Form I of an L-ascorbic acid salt of sunitinib.
    Type: Grant
    Filed: January 6, 2014
    Date of Patent: March 8, 2016
    Assignee: SUN PHARMACEUTICAL INDUSTRIES LIMITED
    Inventors: Hari Babu Matta, Mahavir Singh Khanna, Mohan Prasad
  • Salts of dexlansoprazole and their preparation
    Patent number: 9085556
    Abstract: The present invention relates to the salts of dexlansoprazole in amorphous form. The present invention further relates to processes for the preparation of salts of dexlansoprazole.
    Type: Grant
    Filed: March 29, 2011
    Date of Patent: July 21, 2015
    Assignee: RANBAXY LABORAOTORIES LIMITED
    Inventors: Anu Mittal, Anmol Kumar Ray, Mahavir Singh Khanna, Rajesh Kumar Thaper, Mohan Prasad
  • PURE CRYSTALLINE FORM II OF L-MALIC ACID SALT OF SUNITINIB AND PROCESSES FOR ITS PREPARATION
    Publication number: 20150112085
    Abstract: The present invention relates to pure crystalline Form II of an L-malic acid salt of sunitinib and a process for its preparation. The invention further provides crystalline Form II of an L-malic acid salt of sunitinib having a purity of at least 97.0%. The invention also provides crystalline Form II of an L-malic acid salt of sunitinib substantially free of an anti-oxidant. The invention also provides crystalline Form II of L-malic acid salt of sunitinib which remains chemically pure on storage at 25° C.±2° C. and 40° C.±2° C. at a relative humidity of 60%±5% and 75%±5%, respectively, for at least 1 month.
    Type: Application
    Filed: January 6, 2014
    Publication date: April 23, 2015
    Applicant: RANBAXY LABORATORIES LIMITED
    Inventors: Hari Babu MATTA, Mahavir Singh KHANNA, Mohan PRASAD
  • ASCORBIC ACID SALT OF SUNITINIB
    Publication number: 20150111940
    Abstract: The present invention relates to an ascorbic acid salt of sunitinib and a process for its preparation. The present invention further provides a crystalline Form I of an L-ascorbic acid salt of sunitinib.
    Type: Application
    Filed: January 6, 2014
    Publication date: April 23, 2015
    Applicant: RANBAXY LABORATORIES LIMITED
    Inventors: Hari Babu MATTA, Mahavir Singh KHANNA, Mohan PRASAD
  • PROCESS FOR THE PREPARATION OF DEXLANSOPRAZOLE
    Publication number: 20140357870
    Abstract: The present invention relates to a process for the preparation of dexlansoprazole.xH2O, wherein x is about 0.0 to about 0.1, using dexlansoprazole.xH2O, wherein x is about 2.6 to about 50.
    Type: Application
    Filed: June 20, 2012
    Publication date: December 4, 2014
    Applicant: RANBAXY LABORATORIES LIMITED
    Inventors: Anmol Kumar Ray, Anu Mittal, Nagaraju Gottumukkala, Mahavir Singh Khanna, Rajesh Kumar Thaper, Mohan Prasad, Sudershan Kumar Arora
  • PROCESS FOR THE PREPARATION OF ATAZANAVIR OR ITS BISULFATE SALT
    Publication number: 20140343290
    Abstract: The present invention relates to an improved process for the preparation of atazanavir bisulfate, an inhibitor of retroviral aspartate protease. The process of the present invention comprises conversion of 1,1-dimethylethyl[(2S,3R)-4-chloro-3-hydroxy-phenylbutan-2-yl]carbamate (Formula II) into 1-[4-(pyridine-2-yl)-phenyl]-4(S)-5 hydroxy-2-N-tert-butoxycarbonylamino-5(S)—N—(N-methoxycarbonyl-(L)-tert-leucyl)amino-6-phenyl-2-azahexane (Formula VII) without isolating intermediate compounds formed therein, followed by its subsequent conversion to atazanavir or its bisulfate salt.
    Type: Application
    Filed: July 25, 2012
    Publication date: November 20, 2014
    Inventors: Rakesh Kumar Singh, Nagaraju Gottumukkala, Mahavir Singh Khanna, Rajesh Kumar Thaper, Mohan Prasad, Sudershan Kumar Arora
  • PROCESS FOR THE PREPARATION OF AGOMELATINE
    Publication number: 20140336380
    Abstract: The present invention provides a process for the preparation of agomelatine and its intermediate compounds. The invention also provides an intermediate compound of agomelatine represented by Formula (V).
    Type: Application
    Filed: November 21, 2012
    Publication date: November 13, 2014
    Inventors: Anu Mittal, Mahavir Singh Khanna, Rajesh Kumar Thaper, Mohan Prasad, Sudershan Kumar Arora
  • Process for the preparation of dexlansoprazole
    Patent number: 8853411
    Abstract: The present invention relates to a process for the preparation of crystalline dexlansoprazole.
    Type: Grant
    Filed: March 29, 2011
    Date of Patent: October 7, 2014
    Assignee: Ranbaxy Laboratories Limited
    Inventors: Anu Mittal, Anmol Kumar Ray, Mahavir Singh Khanna, Rajesh Kumar Thaper, Mohan Prasad
  • CRYSTALLINE FORMS OF BOSENTAN SALTS AND PROCESSES FOR THEIR PREPARATION
    Publication number: 20140187569
    Abstract: The present invention relates to crystalline forms of bosentan salts and processes for their preparation.
    Type: Application
    Filed: March 4, 2014
    Publication date: July 3, 2014
    Applicant: RANBAXY LABORATORIES LIMITED
    Inventors: Rakesh SINGH, Anu MITTAL, Gopal Singh BISHT, Mahavir Singh KHANNA, Rajesh Kumar THAPER, Mohan PRASAD
  • CRYSTALLINE FORMS OF BOSENTAN SALTS AND PROCESSES FOR THEIR PREPARATION
    Publication number: 20140187568
    Abstract: The present invention relates to crystalline forms of bosentan salts and processes for their preparation.
    Type: Application
    Filed: March 4, 2014
    Publication date: July 3, 2014
    Applicant: RANBAXY LABORATORIES LIMITED
    Inventors: Rakesh SINGH, Anu MITTAL, Gopal Singh BISHT, Mahavir Singh KHANNA, Rajesh Kumar THAPER, Mohan PRASAD
  • Crystalline forms of bosentan salts and processes for their preparation
    Patent number: 8716477
    Abstract: The present invention relates to crystalline forms of bosentan salts and processes for their preparation.
    Type: Grant
    Filed: November 12, 2010
    Date of Patent: May 6, 2014
    Assignee: Ranbaxy Laboratories Limited
    Inventors: Rakesh Singh, Anu Mittal, Gopal Singh Bisht, Mahavir Singh Khanna, Rajesh Kumar Thaper, Mohan Prasad
  • PROCESS FOR THE PREPARATION OF DEXLANSOPRAZOLE
    Publication number: 20130204002
    Abstract: The present invention relates to a process for the preparation of crystalline dexlansoprazole.
    Type: Application
    Filed: March 29, 2011
    Publication date: August 8, 2013
    Applicant: RANBAXY LABORATORIES LIMITED
    Inventors: Anu Mittal, Anmol Kumar Ray, Mahavir Singh Khanna, Rajesh Kumar Thaper, Mohan Prasad
  • SALTS OF DEXLANSOPRAZOLE AND THEIR PREPARATION
    Publication number: 20130197233
    Abstract: The present invention relates to the salts of dexlansoprazole in amorphous form. The present invention further relates to processes for the preparation of salts of dexlansoprazole.
    Type: Application
    Filed: March 29, 2011
    Publication date: August 1, 2013
    Applicant: RANBAXY LABORATORIES LIMITED
    Inventors: Anu Mittal, Anmol Kumar Ray, Mahavir Singh Khanna, Rajesh Kumar Thaper, Mohan Prasad
  • PROCESS FOR THE PREPARATION OF CRYSTALLINE FORMS OF DEXLANSOPRAZOLE
    Publication number: 20130197232
    Abstract: The present invention relates to crystalline forms of dexlansoprazole designated as forms A and B, and their preparation. The present invention further relates to processes for the preparation of anhydrous dexlansoprazole and dexlansoprazole sesquihydrate using crystalline Forms A and B of dexlansoprazole.
    Type: Application
    Filed: January 28, 2011
    Publication date: August 1, 2013
    Applicant: RANBAXY LABORATORIES LIMITED
    Inventors: Anmol Kumar Ray, Mahavir Singh Khanna, Rajesh Kumar Thaper, Mohan Prasad
  • Barium salt of benzimidazole derivative
    Patent number: 8415478
    Abstract: The invention relates to crystalline barium salt of (S)-omeprazole, which is (S)-5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)-methyl]sulfinyl]-1H-benzimidazole. The invention also relates to processes for preparing crystalline barium salt of (S)-omeprazole and pharmaceutical compositions that include the crystalline barium salt of (S)-omeprazole so prepared.
    Type: Grant
    Filed: February 9, 2010
    Date of Patent: April 9, 2013
    Assignee: Ranbaxy Laboratories Limited
    Inventors: Yatendra Kumar, Mahavir Singh Khanna, Mohan Prasad