Abstract: Provided herein is a microfluidic chip for sorting cells with an actuator assembly that relies on one or more feedback-controlled piezoelectric actuators to divert sample fluid flowing along a sample fluid path in a sample fluid line into one or more desired outlets. Also provided are methods of use.

Abstract: Integrated circuit structures having dual stress gates are described. For example, an integrated circuit structure includes a first vertical stack of horizontal nanowires, and a second vertical stack of nanowires laterally spaced apart from the first vertical stack of horizontal nanowires. An NMOS gate electrode is over the first vertical stack of horizontal nanowires, the NMOS gate electrode having a tensile layer extending from a top to a bottom of the first vertical stack of horizontal nanowires. A PMOS gate electrode is over the second vertical stack of horizontal nanowires, the PMOS gate electrode having a compressive layer extending from a top to a bottom of the second vertical stack of horizontal nanowires. The tensile layer of the NMOS gate electrode is not included in the PMOS gate electrode.

Abstract: A device includes a substrate, an electrode, an electrical pad, and a signal line. The signal line is coupled to the substrate and covered by an insulation layer. The signal line is coupled to the electrical pad and the electrode. At least one of the electrode and the signal line includes a diamagnetic material and paramagnetic material, wherein a ratio of the diamagnetic material and the paramagnetic material is selected based on the susceptibility properties of a physiological tissue. The term paramagnetic herein refers to magnetic susceptibility greater than that of the surrounding tissue and diamagnetic refers to magnetic susceptibility lower than that of the tissue.

Abstract: The present embodiments relate to an apheretic system incorporating one or more centrifuge devices. A biological fluid containing cells (or another fluid) can be obtained and directed to a centrifuge device to separate particles by a particle size and/or a flow rate. The centrifuge device can include a center-axis centrifuge, an off-center centrifuge, and/or a hydro-cyclone centrifuge device. The separated particles can be directed/drawn into either an outlet to a return or into a collection container for further testing.

Abstract: The present embodiments relate to an apheretic system incorporating one or more centrifuge devices. A biological fluid containing cells (or another fluid) can be obtained and directed to a centrifuge device to separate particles by a particle size and/or a flow rate. The centrifuge device can include a center-axis centrifuge, an off-center centrifuge, and/or a hydro-cyclone centrifuge device. The separated particles can be directed/drawn into either an outlet to a return or into a collection container for further testing.

Abstract: A temperature measuring circuit uses a diode to drain a switched capacitor at two different lengths of time. The capacitor's voltage is amplified, measured, and compared for each length of time to calculate a temperature. The circuitry may cancel out errors due to manufacturing tolerances and variations, as well as offset voltages, supply noise, substrate noise, and other issues. The process may charge a capacitor, then drain the capacitor with a diode for a first period of time, at which point, the diode is switched out of the circuit. The remaining charge in the diode may be amplified, then analyzed using an analog to digital converter. A second measurement may be taken with a different period of time, and the two measurements may be subtracted to yield an absolute temperature.

Abstract: A device includes a substrate, an electrode, an electrical pad, and a signal line. The signal line is coupled to the substrate and covered by an insulation layer. The signal line is coupled to the electrical pad and the electrode. At least one of the electrode and the signal line includes a diamagnetic material and paramagnetic material, wherein a ratio of the diamagnetic material and the paramagnetic material is selected based on the susceptibility properties of a physiological tissue. The term paramagnetic herein refers to magnetic susceptibility greater than that of the surrounding tissue and diamagnetic refers to magnetic susceptibility lower than that of the tissue.

Abstract: A device includes a substrate, an electrode, an electrical pad, and a signal line. The signal line is coupled to the substrate and covered by an insulation layer. The signal line is coupled to the electrical pad and the electrode. At least one of the electrode and the signal line includes a diamagnetic material and paramagnetic material, wherein a ratio of the diamagnetic material and the paramagnetic material is selected based on the susceptibility properties of a physiological tissue. The term paramagnetic herein refers to magnetic susceptibility greater than that of the surrounding tissue and diamagnetic refers to magnetic susceptibility lower than that of the tissue.

Abstract: Some implementations provide a passive equalizer section configured to filter an input signal, the passive equalizer section including: a first passive filter that comprises: a first resistor characterized by a first resistance, and a first reactive component characterized by a first reactance, wherein the first resistor and the first reactive component are in series and connected at a first connection node; and a second passive filter that comprises: a second resistor characterized by a second resistance, and a second reactive component characterized by a second reactance, wherein the second resistor and the second reactive component are in series and connected at a second connection node; and a signal mixing section comprising a plurality of transistors to mix signals with different frequency response characteristics.

Abstract: A circuit for charge-balanced current-controlled stimulation. The circuit includes a transistor differential pair, a first current mirror, a second current mirror, and a third current mirror. The transistor differential pair includes a first differential input node, a second differential input node, a first differential output node, a second differential output node, and a common node. The transistor differential pair is configured to generate a first differential current that passes through the first differential output node and a second differential current that passes through the second differential output node. The first current mirror is configured to generate a first mirrored current based on the first differential current. The second current mirror is configured to generate a second mirrored current based on the second differential current. The third current mirror is configured to generate a third mirrored current based on the first mirrored current.

Abstract: Implementations provide a receiver circuit that includes: an alternate current (AC)-coupling network to filter an input signal, the AC-coupling network including a first RC filter connected between a first input node and a first common node and a second RC filter connected between a second input node and the first common node; a differential amplifier coupled to the AC-coupling network and configured to receive a filtered input signal from the AC-coupling network and generate an output signal, the differential amplifier including a differential pair of transistors and a common-mode measurement network coupled to source terminals of a first and a second transistors in the differential pair; and a first operational amplifier having an input coupled to output terminal of the common-mode measurement network and an output coupled to the first common node.

Abstract: Some implementations provide a passive equalizer section configured to filter an input signal, the passive equalizer section including: a first passive filter that comprises: a first resistor characterized by a first resistance, and a first reactive component characterized by a first reactance, wherein the first resistor and the first reactive component are in series and connected at a first connection node; and a second passive filter that comprises: a second resistor characterized by a second resistance, and a second reactive component characterized by a second reactance, wherein the second resistor and the second reactive component are in series and connected at a second connection node; and a signal mixing section comprising a plurality of transistors to mix signals with different frequency response characteristics.

Abstract: Some implementations provide a passive equalizer section configured to filter an input signal, the passive equalizer section including: a first passive filter that comprises: a first resistor characterized by a first resistance, and a first reactive component characterized by a first reactance, wherein the first resistor and the first reactive component are in series and connected at a first connection node; and a second passive filter that comprises: a second resistor characterized by a second resistance, and a second reactive component characterized by a second reactance, wherein the second resistor and the second reactive component are in series and connected at a second connection node; and a signal mixing section comprising a plurality of transistors to mix signals with different frequency response characteristics.

Abstract: Implementations provide a receiver circuit that includes: an alternate current (AC)-coupling network to filter an input signal, the AC-coupling network including a first RC filter connected between a first input node and a first common node and a second RC filter connected between a second input node and the first common node; a differential amplifier coupled to the AC-coupling network and configured to receive a filtered input signal from the AC-coupling network and generate an output signal, the differential amplifier including a differential pair of transistors and a common-mode measurement network coupled to source terminals of a first and a second transistors in the differential pair; and a first operational amplifier having an input coupled to output terminal of the common-mode measurement network and an output coupled to the first common node.

Abstract: A class-E power oscillator (PO) is disclosed. The class-E PO includes a first inductor, a switch, a first capacitor, a resonant circuit, and a feedback network. The first inductor is coupled in series to a first power supply. The switch is connected between the first inductor and a primary common node. The first capacitor is connected between the first inductor and the primary common node. The resonant circuit includes a second inductor, a second capacitor, and a resistor. The second inductor is connected between the first inductor and the primary common node. The second capacitor is connected between the first inductor and the primary common node, and is coupled in series to the second inductor. The resistor is connected between the first inductor and the primary common node, and is coupled in series to the second inductor. The feedback network is connected between the switch and a feedback node. The feedback node is located between the second inductor and the second capacitor.

Abstract: A circuit for charge-balanced current-controlled stimulation. The circuit includes a transistor differential pair, a first current mirror, a second current mirror, and a third current mirror. The transistor differential pair includes a first differential input node, a second differential input node, a first differential output node, a second differential output node, and a common node. The transistor differential pair is configured to generate a first differential current that passes through the first differential output node and a second differential current that passes through the second differential output node. The first current mirror is configured to generate a first mirrored current based on the first differential current. The second current mirror is configured to generate a second mirrored current based on the second differential current. The third current mirror is configured to generate a third mirrored current based on the first mirrored current.

Abstract: A class-E power oscillator (PO) is disclosed. The class-E PO includes a first inductor, a switch, a first capacitor, a resonant circuit, and a feedback network. The first inductor is coupled in series to a first power supply. The switch is connected between the first inductor and a primary common node. The first capacitor is connected between the first inductor and the primary common node. The resonant circuit includes a second inductor, a second capacitor, and a resistor. The second inductor is connected between the first inductor and the primary common node. The second capacitor is connected between the first inductor and the primary common node, and is coupled in series to the second inductor. The resistor is connected between the first inductor and the primary common node, and is coupled in series to the second inductor. The feedback network is connected between the switch and a feedback node. The feedback node is located between the second inductor and the second capacitor.

Abstract: A pressure sensing catheter system includes a urethral catheter and a sensor array formed on the urethral catheter. The sensor array includes a plurality of pressure sensors distributed along a length of the urethral catheter. The sensor array is configured to produce a dynamic pressure distribution profile along a urethra.

Abstract: A device includes a substrate, an electrode, an electrical pad, and a signal line. The signal line is coupled to the substrate and covered by an insulation layer. The signal line is coupled to the electrical pad and the electrode. At least one of the electrode and the signal line includes a diamagnetic material and paramagnetic material, wherein a ratio of the diamagnetic material and the paramagnetic material is selected based on the susceptibility properties of a physiological tissue. The term paramagnetic herein refers to magnetic susceptibility greater than that of the surrounding tissue and diamagnetic refers to magnetic susceptibility lower than that of the tissue.

Abstract: A pressure sensing catheter system includes a urethral catheter and a sensor array formed on the urethral catheter. The sensor array includes a plurality of pressure sensors distributed along a length of the urethral catheter. The sensor array is configured to produce a dynamic pressure distribution profile along a urethra.