Patents by Inventor Mahender Rao Siripragada

Mahender Rao Siripragada has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IMPROVED PROCESS FOR THE PREPARATION OF SEMAGLUTIDE
    Publication number: 20230220036
    Abstract: Improved process for the preparation of Semaglutide having the structural formula (I). His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys (C18 di acid mono-t-butyl-?-Glu(AEEA-AEEA)-OtBu)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly-OH?? Formula-I The present invention relates to the following fragments which are useful in the preparation of Semaglutide.
    Type: Application
    Filed: April 30, 2021
    Publication date: July 13, 2023
    Inventors: Khalid Anwer MOHAMMED, Rehana BEGUM, Shavali SHAIK, Kalesha SHAIK, Sunil Kumar GANDAVADI, Mohammed Sharif SHAIK, Mohosin LAYEK, Mahender Rao SIRIPRAGADA, Pavan Kumar JUJJURI, Hema Sundara Rao TELAKALA
  • Solid state forms of Venetoclax and its process for the preparation there of
    Patent number: 11613540
    Abstract: The present invention provides solid state forms of Venetoclax, particularly relates to novel alkali metal salt and/or DMF solvate form of Venetoclax or its salt. The present invention also relates to process for the preparation Venetoclax by using the said solid state form of Venetoclax.
    Type: Grant
    Filed: January 5, 2021
    Date of Patent: March 28, 2023
    Assignee: Alembic Pharmaceuticals Limited
    Inventors: Vittal Tvsk, Dinesh Chudasama, Saisuryanarayana Donthukurthi, Tejas Shah, Chetan Patil, Mahendar Velisoju, Mahender Rao Siripragada
  • Solid State Forms Of Venetoclax And Its Process For The Preparation There Of
    Publication number: 20210130350
    Abstract: The present invention provides solid state forms of Venetoclax, particularly relates to novel alkali metal salt and/or DMF solvate form of Venetoclax or its salt. The present invention also relates to process for the preparation Venetoclax by using the said solid state form of Venetoclax.
    Type: Application
    Filed: January 5, 2021
    Publication date: May 6, 2021
    Applicant: Alembic Pharmaceuticals Limited
    Inventors: Vittal Tvsk, Dinesh Chudasama, Saisuryanarayana Donthukurthi, Tejas Shah, Chetan Patil, Mahendar Velisoju, Mahender Rao Siripragada
  • Solid state forms of venetoclax and its process for the preparation there of
    Patent number: 10934289
    Abstract: The present invention provides solid state forms of Venetoclax, particularly relates to novel alkali metal salt and/or DMF solvate form of Venetoclax or its salt. The present invention also relates to process for the preparation Venetoclax by using the said solid state form of Venetoclax.
    Type: Grant
    Filed: January 29, 2019
    Date of Patent: March 2, 2021
    Assignee: Alembic Pharmaceuticals Limited
    Inventors: Vittal Tvsk, Dinesh Chudasama, Saisuryanarayana Donthukurthi, Tejas Shah, Chetan Patil, Mahendar Velisoju, Mahender Rao Siripragada
  • Solid State Forms Of Venetoclax And Its Process For The Preparation There Of
    Publication number: 20200354361
    Abstract: The present invention provides solid state forms of Venetoclax, particularly relates to novel alkali metal salt and/or DMF solvate form of Venetoclax or its salt. The present invention also relates to process for the preparation Venetoclax by using the said solid state form of Venetoclax.
    Type: Application
    Filed: January 29, 2019
    Publication date: November 12, 2020
    Applicant: Alembic Pharmaceuticals Limited
    Inventors: Vittal Tvsk, Dinesh Chudasama, Saisuryanarayana Donthukurthi, Tejas Shah, Chetan Patil, Mahendar Velisoju, Mahender Rao Siripragada
  • Processes for the preparation of 2,5-dihydroxybenzenesulfonic acid salts
    Patent number: 10632085
    Abstract: Processes for the preparation of 2,5-dihydroxybenzenesulfonic acid salts of formula (I) and a crystalline form of potassium 2,5-dihydroxybenzenesulfonic acid are provided. Also provided are methods of treating psoriasis comprising administering crystalline forms of potassium 2,5-dihydroxybenzenesulfonic acid.
    Type: Grant
    Filed: April 23, 2018
    Date of Patent: April 28, 2020
    Assignee: AmDerma Pharmaceuticals, LLC
    Inventors: Unni Santhosh, Annadurai Marimuthu Senthilkumar, Bodireddy Mohan Reddy, Rajendran Kamala, Mahender Rao Siripragada
  • Polymorph of Riociguat and its process for the preparation
    Patent number: 10414766
    Abstract: The present invention relates to novel polymorph of riociguat and process for preparing the polymorph. The present invention also relates to the improved process for the preparation of riociguat.
    Type: Grant
    Filed: December 12, 2016
    Date of Patent: September 17, 2019
    Assignee: ALEMBIC PHARMACEUTICALS LIMITED
    Inventors: Mahender Rao Siripragada, Mahendar Velisoju, Tejas Shah, Chetan Patil, Kalpesh Jadav, Ashvinkumar Bhuva, Saisuryanaraya Donthukurthi
  • Process and novel polymorphic form of Apremilast
    Patent number: 10399942
    Abstract: The present invention provides an improved process for the preparation of Apremilast using novel intermediates. The present invention also relates to the novel crystalline polymorphic form of Apremilast.
    Type: Grant
    Filed: July 29, 2016
    Date of Patent: September 3, 2019
    Assignee: Alembic Pharmaceuticals Limited
    Inventors: Mahender Rao Siripragada, Dinesh Panchasara, Ilesh Patel, Bhavesh Prajapati, Ankit Shah, Ananda Babu Thirunavakarasu, Pinky Parikh
  • NOVEL POLYMORPH OF RIOCIGUAT AND ITS PROCESS FOR THE PREPARATION
    Publication number: 20190002461
    Abstract: The present invention relates to novel polymorph of riociguat and process for preparing the polymorph. The present invention also relates to the improved process for the preparation of riociguat.
    Type: Application
    Filed: December 12, 2016
    Publication date: January 3, 2019
    Inventors: Mahender Rao SIRIPRAGADA, Mahendar VELISOJU, Tejas SHAH, Chetan PATIL, Kalpesh JADAV, Ashvinkumar BHUVA, Saisuryanaraya DONTHUKURTHI
  • IMPROVED PROCESS AND NOVEL POLYMORPHIC FORM OF APREMILAST
    Publication number: 20180327356
    Abstract: The present invention provides an improved process for the preparation of Apremilast using novel intermediates. The present invention also relates to the novel crystalline polymorphic form of Apremilast.
    Type: Application
    Filed: July 29, 2016
    Publication date: November 15, 2018
    Applicant: Alembic Pharmaceuticals Limited
    Inventors: Mahender Rao Siripragada, Dinesh Panchasara, Ilesh Patel, Bhavesh Prajapati, Ankit Shah, Ananda Babu Thirunavakarasu, Pinky Parikh
  • Processes For The Preparation Of 2,5-Dihydroxybenzenesulfonic Acid Salts
    Publication number: 20180289645
    Abstract: Processes for the preparation of 2,5-dihydroxybenzenesulfonic acid salts of formula (I) and a crystalline form of potassium 2,5-dihydroxybenzenesulfonic acid are provided. Also provided are methods of treating psoriasis comprising administering crystalline forms of potassium 2,5-dihydroxybenzenesulfonic acid.
    Type: Application
    Filed: April 23, 2018
    Publication date: October 11, 2018
    Inventors: Unni Santhosh, Annadurai Marimuthu Senthilkumar, Bodireddy Mohan Reddy, Rajendran Kamala, Mahender Rao Siripragada
  • Processes for the preparation of 2,5-dihydroxybenzenesulfonic acid salts
    Patent number: 10052294
    Abstract: Processes for the preparation of 2,5-dihydroxybenzenesulfonic acid salts of formula (I) and a crystalline form of potassium 2,5-dihydroxybenzenesulfonic acid are provided. Also provided are methods of treating rosacea comprising administering crystalline forms of potassium 2,5-dihydroxybenzenesulfonic acid.
    Type: Grant
    Filed: November 23, 2015
    Date of Patent: August 21, 2018
    Assignee: AmDerma Pharmaceuticals, LLC
    Inventors: Unni Santhosh, Annadurai Marimuthu Senthilkumar, Bodireddy Mohan Reddy, Rajendran Kamala, Mahender Rao Siripragada
  • Processes for the preparation of 2,5-dihydroxybenzenesulfonic acid salts
    Patent number: 9801838
    Abstract: Processes for the preparation of 2,5-dihydroxybenzenesulfonic acid salts of formula (I) and a crystalline form of potassium 2,5 2,5-dihydroxybenzenesulfonic acid are provided.
    Type: Grant
    Filed: March 10, 2015
    Date of Patent: October 31, 2017
    Assignee: AMDERMA PHARMACEUTICALS, LLC
    Inventors: Unni Santhosh, Annadurai Marimuthu Senthilkumar, Bodireddy Mohan Reddy, Rajendran Kamala, Mahender Rao Siripragada
  • Processes For The Preparation Of 2,5-Dihydroxybenzenesulfonic Acid Salts
    Publication number: 20160074347
    Abstract: Processes for the preparation of 2,5-dihydroxybenzenesulfonic acid salts of formula (I) and a crystalline form of potassium 2,5-dihydroxybenzenesulfonic acid are provided. Also provided are methods of treating rosacea comprising administering crystalline forms of potassium 2,5-dihydroxybenzenesulfonic acid.
    Type: Application
    Filed: November 23, 2015
    Publication date: March 17, 2016
    Inventors: Unni Santhosh, Annadurai Marimuthu Senthilkumar, Bodireddy Mohan Reddy, Rajendran Kamala, Mahender Rao Siripragada
  • Processes for the preparation of 2,5-dihydroxybenzenesulfonic acid salts
    Patent number: 9227928
    Abstract: Processes for the preparation of 2,5-dihydroxybenzenesulfonic acid salts of formula (I) and a crystalline form of potassium 2,5 2,5-dihydroxybenzenesulfonic acid are provided.
    Type: Grant
    Filed: January 4, 2012
    Date of Patent: January 5, 2016
    Assignee: AmDerma Pharmaceuticals, LLC
    Inventors: Unni Santhosh, Annadurai Marimuthu Senthilkumar, Bodireddy Mohan Reddy, Rajendran Kamala, Mahender Rao Siripragada
  • Processes For The Preparation Of 2,5-Dihydroxybenzenesulfonic Acid Salts
    Publication number: 20150183732
    Abstract: Processes for the preparation of 2,5-dihydroxybenzenesulfonic acid salts of formula (I) and a crystalline form of potassium 2,5 2,5-dihydroxybenzenesulfonic acid are provided.
    Type: Application
    Filed: March 10, 2015
    Publication date: July 2, 2015
    Inventors: Unni Santhosh, Annadurai Marimuthu Senthilkumar, Bodireddy Mohan Reddy, Rajendran Kamala, Mahender Rao Siripragada
  • Processes for the preparation of 2,5-dihydroxybenzenesulfonic acid salts
    Patent number: 9012692
    Abstract: Processes for the preparation of 2,5-dihydroxybenzenesulfonic acid salts of formula (I) and a crystalline form of potassium 2,5 2,5-dihydroxybenzenesulfonic acid are provided.
    Type: Grant
    Filed: January 2, 2009
    Date of Patent: April 21, 2015
    Assignee: AmDerma Pharmaceuticals, LLC
    Inventors: Unni Santhosh, Annadurai Marimuthu Senthilkumar, Bodireddy Mohan Reddy, Rajendran Kamala, Mahender Rao Siripragada
  • Processes For The Preparation Of 2,5-Dihydroxybenzenesulfonic Acid Salts
    Publication number: 20120149938
    Abstract: Processes for the preparation of 2,5-dihydroxybenzenesulfonic acid salts of formula (I) and a crystalline form of potassium 2,5 2,5-dihydroxybenzenesulfonic acid are provided.
    Type: Application
    Filed: January 4, 2012
    Publication date: June 14, 2012
    Applicant: AmDerma Pharmaceuticals, LLC
    Inventors: Unni Santhosh, Annadurai Marimuthu Senthilkumar, Bodireddy Mohan Reddy, Rajendran Kamala, Mahender Rao Siripragada
  • PROCESSES FOR THE PREPARATION OF 2,5-DIHYDROXYBENZENESULFONIC ACID SALTS
    Publication number: 20110144337
    Abstract: Processes for the preparation of 2,5-dihydroxybenzenesulfonic acid salts of formula (I) and a crystalline form of potassium 2,5 2,5-dihydroxybenzenesulfonic acid are provided.
    Type: Application
    Filed: January 2, 2009
    Publication date: June 16, 2011
    Applicant: Action Medicines S.L.
    Inventors: Unni Santhosh, Annadurai Marimuthu Senthilkumar, Bodireddy Mohan Reddy, Rajendran Kamala, Mahender Rao Siripragada
  • METHOD FOR THE PREPARATION OF DULOXETINE HYDROCHLORIDE
    Publication number: 20100267968
    Abstract: The present invention relates to an improved process for the preparation of Duloxetine and its intermediates (S)-(+)-N,N-dimethyl-3-(1-naphthalenyloxy)-3-(2-thienyl)propanamine by reacting (S)-(+)-N,N-dimethyl-3-(2-thienyl)-3-hydroxypropanamine with 1-fluoronaphthalene in the presence of a base; wherein the improvement lies in conducting the reaction in the absence of solvent.
    Type: Application
    Filed: December 26, 2008
    Publication date: October 21, 2010
    Applicant: ORCHID CHEMICALS & PHARMACEUTICALS LIMITED
    Inventors: Mahender Rao Siripragada, Arulmoli Thangavel, Muthulingham Arunagiri, Prasadachari Yarroju, Kiranmye Tayyala