Patents by Inventor Mahendra R. Patel

Mahendra R. Patel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6201153
    Abstract: Midodrine hydrochloride, ±1-(2′,5′-dimethoxyphenyl)-2-glycineamido-ethanol-(1)-HCl, is prepared from a novel intermediate, 1-(2′,5′-dimethoxyphenyl)-2-azidoethanone.
    Type: Grant
    Filed: April 17, 2000
    Date of Patent: March 13, 2001
    Assignee: Geneva Pharmaceuticals Inc.
    Inventors: Anup K. Ray, Hiren Patel, Mahendra R. Patel
  • Patent number: 5756124
    Abstract: A solid pharmaceutical tablet having a predetermined dosage that can be divided into a plurality of sub-dosage units by applying a minimal amount of force to the tablet. The tablet comprises a solid body having a top surface, a bottom surface, an outer surface, and an inner surface. The inner surface defines an aperture having a shape corresponding to the shape of the tablet. The area of the aperture is at least 15% of the area of the tablet. Impressed within the top surface of the tablet are a first plurality of symmetrical score lines and impressed within the bottom surface of the tablet are a second plurality of symmetrical score lines. The score lines extend from the aperture to the outer surface of the tablet. Finally, each of the sub-dosage units has a dosage that is a fraction of the predetermined dosage of the tablet.
    Type: Grant
    Filed: August 9, 1996
    Date of Patent: May 26, 1998
    Assignee: Invamed, Inc.
    Inventors: Mahendra R. Patel, Rajendra Patel
  • Patent number: 5587377
    Abstract: The present invention relates to the discovery of novel polymorph form of an active pharmaceutical agent and the process for its preparation. More specifically, the present invention relates to the preparation of a novel polymorph form of terazosin hydrochloride, a well known anti-hypertensive agent.
    Type: Grant
    Filed: October 24, 1995
    Date of Patent: December 24, 1996
    Assignee: Invamed, Inc.
    Inventors: Mahendra R. Patel, Kasireddy C. Reddy, Pankaj J. Dave
  • Patent number: 4505890
    Abstract: A controlled release pharmaceutical formulation which undergoes substantially zero order release of active drug is provided, preferably in the form of a coated tablet, containing a core portion from which the angiotensin converting enzyme inhibitor (S)-1-[3-(benzoylthio)-2-methyl-1-oxopropyl]-L-proline is slowly released over a controlled length of time. The core also includes one or more hydrocolloid gelling agents having a viscosity of within the range of from about 8000 to about 100,00 centipoises in 2% solution at 20.degree. C., such as hydroxypropylmethyl cellulose and/or methyl cellulose, one or more inert fillers or excipients, one or more lubricants, and optionally one or more anti-adherents such as silicon dioxide and water. The above-described core is coated with a conventional pharmaceutical coating composition. A method of using such controlled release formulations in treating hypertension is also provided.
    Type: Grant
    Filed: June 30, 1983
    Date of Patent: March 19, 1985
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Nemichand B. Jain, Mahendra R. Patel
  • Patent number: 4327080
    Abstract: New bendroflumethiazide formulations in solid form are provided which are characterized by excellent disintegration and dissolution capabilities even after long periods of storage. The new bendroflumethiazide formulations, for example, in the form of tablets, are formed of one or more excipients and a dry granulation containing one or more fillers, such as lactose and starch, and a preformed partial coprecipitate of bendroflumethiazide and a wetting agent therefor, such as polyvinyl pyrrolidone which converts the bendroflumethiazide into a more hydrophilic form.
    Type: Grant
    Filed: July 13, 1981
    Date of Patent: April 27, 1982
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Thomas M. Wong, Mahendra R. Patel
  • Patent number: 4304773
    Abstract: New bendroflumethiazide formulations in solid form are provided which are characterized by excellent disintegration and dissolution capabilities even after long periods of storage. The new bendroflumethiazide formulations, for example, in the form of tablets, contain in addition to bendroflumethiazide, a combination of microcrystalline cellulose which serves as a diluent and aids in disintegration of the tablets, lactose which serves as a diluent, optionally starch (in the gelatinized form) which serves as a disintegrant, and one or more auxilliary disintegrants, such as sodium carboxymethyl starch, a tablet lubricant, such as magnesium stearate, and a colorant, if desired.A method for preparing the above formulations is also provided.
    Type: Grant
    Filed: June 26, 1980
    Date of Patent: December 8, 1981
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Thomas M. Wong, Mahendra R. Patel