Patents by Inventor Mahesh H. Goghari

Mahesh H. Goghari has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fluorine containing atrial natriuretic peptides
    Patent number: 5376635
    Abstract: Disclosed herein are derivatives of atrial natriuretic peptides which are characterized by having (at positions 106 and/or 124) a phenylalanyl residue bearing a fluoro or trifluoromethyl substituent on the aromatic portion thereof. Optionally, the exocyclic N-terminal peptide segment and the first cystienyl residue (at position 105) are replaced by an optionally substituted thioalkanoyl residue. The derivatives possess useful diuretic, natriuretic and antihypertensive activities.
    Type: Grant
    Filed: October 23, 1991
    Date of Patent: December 27, 1994
    Assignee: Bio-Mega/Boehringer Ingelheim Research Inc.
    Inventors: Sumanas Rakhit, Mahesh H. Goghari
  • Fluorine containing atrial natriuretic peptides
    Patent number: 5095004
    Abstract: Disclosed herein are derivatives of atrial natriuretic peptides which are characterized by having (at position 124 or at positions 106 and 124) a phenylalanyl residue bearing a fluoro or trifluoromethyl substituent on the aromatic portion thereof. Optionally, the exocyclic N-terminal peptide segment and the first cystienyl residue (at position 105) are replaced by an optionally substituted thioalkanoyl residue. The derivatives possess useful diuretic, natriuretic and antihypertensive activities.
    Type: Grant
    Filed: March 14, 1988
    Date of Patent: March 10, 1992
    Assignee: Bio-Mega Inc.
    Inventors: Sumanas Rakhit, Mahesh H. Goghari