Patents by Inventor Mahesh V. Chaubal

Mahesh V. Chaubal has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR DRUG DELIVERY
    Publication number: 20210251900
    Abstract: The present disclosure is directed to surface-modified particles and to methods of making and using the same.
    Type: Application
    Filed: March 9, 2021
    Publication date: August 19, 2021
    Inventors: Barrett Rabinow, Shawn F. Bairstow, Mahesh V. Chaubal, Sarah Lee, Jane Werling
  • Compositions and methods for drug delivery
    Patent number: 10952965
    Abstract: The present disclosure is directed to surface-modified particles and to methods of making and using the same.
    Type: Grant
    Filed: May 15, 2009
    Date of Patent: March 23, 2021
    Assignees: Baxter International Inc., Baxter Healthcare SA
    Inventors: Barrett Rabinow, Shawn F. Bairstow, Mahesh V. Chaubal, Sarah Lee, Jane Werling
  • PHOSPHORUS-CONTAINING COMPOUNDS WITH POLYMERIC CHAINS, AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20130023688
    Abstract: The present invention relates to novel phosphorus-containing compounds with polymeric chains, and methods of making and using the same. In part, subject compositions containing phosphorus-containing compounds with polymeric chains and a therapeutic agent, and methods of making and using the same, are described. Certain of the subject compositions exhibit reverse thermal gelation.
    Type: Application
    Filed: July 24, 2012
    Publication date: January 24, 2013
    Applicant: Eisai Inc.
    Inventors: Keith Branham, Mahesh V. Chaubal, James P. English, Donna Hall, Zhong Zhao
  • Phosphorus-containing compounds with polymeric chains, and methods of making and using the same
    Patent number: 8258255
    Abstract: The present invention relates to novel phosphorus-containing compounds with polymeric chains, and methods of making and using the same. In part, subject compositions containing phosphorus-containing compounds with polymeric chains and a therapeutic agent, and methods of making and using the same, are described. Certain of the subject compositions exhibit reverse thermal gelation.
    Type: Grant
    Filed: January 22, 2010
    Date of Patent: September 4, 2012
    Assignee: Eisai Inc.
    Inventors: Keith Branham, Mahesh V. Chaubal, James P. English, Donna Hall, Zhong Zhao
  • Submicron Particles of Antineoplastic Agents
    Publication number: 20120070498
    Abstract: The present invention is concerned with the formation of submicron particles of an antineoplastic agent, particularly paclitaxel, by precipitating the antineoplastic agent in an aqueous medium to form a pre-suspension followed by homogenization. Surfactants with phospholipids conjugated with a water soluble or hydrophilic polymer such as PEG are used as coating for the particles. The particles produced generally have an average particle size of less than about 1000 nm and are not rapidly soluble.
    Type: Application
    Filed: September 23, 2011
    Publication date: March 22, 2012
    Applicants: Baxter Healthcare S.A., BAXTER INTERNATIONAL INC.
    Inventors: Mahesh V. Chaubal, Jane Werling, Barrett Rabinow
  • Compositions and Methods for Drug Delivery
    Publication number: 20100290983
    Abstract: The present disclosure is directed to surface-modified particles and to methods of making and using the same.
    Type: Application
    Filed: May 15, 2009
    Publication date: November 18, 2010
    Applicants: BAXTER INTERNATIONAL INC., BAXTER HEALTHCARE S.A.
    Inventors: Barrett Rabinow, Shawn F. Bairstow, Mahesh V. Chaubal, Sarah Lee, Jane Werling
  • Phosphorus-Containing Compounds with Polymeric Chains, and Methods of Making and Using the Same
    Publication number: 20100267924
    Abstract: The present invention relates to novel phosphorus-containing compounds with polymeric chains, and methods of making and using the same. In part, subject compositions containing phosphorus-containing compounds with polymeric chains and a therapeutic agent, and methods of making and using the same, are described. Certain of the subject compositions exhibit reverse thermal gelation.
    Type: Application
    Filed: January 22, 2010
    Publication date: October 21, 2010
    Applicant: Eisai Inc.
    Inventors: Keith Branham, Mahesh V. Chaubal, James P. English, Donna Hall, Zhong Zhao
  • Phosphorus-containing compounds with polymeric chains, and methods of making and using the same
    Patent number: 7674875
    Abstract: The present invention relates to novel phosphorus-containing compounds with polymeric chains, and methods of making and using the same. In part, subject compositions containing phosphorus-containing compounds with polymeric chains and a therapeutic agent, and methods of making and using the same, are described. Certain of the subject compositions exhibit reverse thermal gelation.
    Type: Grant
    Filed: January 16, 2009
    Date of Patent: March 9, 2010
    Assignee: Eisai Inc.
    Inventors: Keith Branham, Mahesh V. Chaubal, James P. English, Donna Hall, Zhong Zhao
  • Phosphorus-Containing Compounds with Polymeric Chains, and Methods of Making and Using the Same
    Publication number: 20090247778
    Abstract: The present invention relates to novel phosphorus-containing compounds with polymeric chains, and methods of making and using the same. In part, subject compositions containing phosphorus-containing compounds with polymeric chains and a therapeutic agent, and methods of making and using the same, are described. Certain of the subject compositions exhibit reverse thermal gelation.
    Type: Application
    Filed: January 16, 2009
    Publication date: October 1, 2009
    Applicant: Eisai Corporation of North America
    Inventors: Keith Branham, Mahesh V. Chaubal, James P. English, Donna Hall, Zhong Zhao
  • Phosphorous-containing compounds with polymeric chains, and methods of making and using the same
    Patent number: 7479535
    Abstract: The present invention relates to novel phosphorus-containing compounds with polymeric chains, and methods of making and using the same. In part, subject compositions containing phosphorus-containing compounds with polymeric chains and a therapeutic agent, and methods of making and using the same, are described. Certain of the subject compositions exhibit reverse thermal gelation.
    Type: Grant
    Filed: February 25, 2003
    Date of Patent: January 20, 2009
    Assignee: Guilford Pharmaceuticals, Inc.
    Inventors: Keith Branham, Mahesh V. Chaubal, James P. English, Donna Hall, Zhong Zhao