Patents by Inventor Mahfoud Assem

Mahfoud Assem has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Genotyping assay to predict cytochrome P4503A5 exression
    Publication number: 20060110767
    Abstract: Genetic polymorphisms responsible or associated with altered expression of cytochrome P450 CYP3A5 enzyme are described. Single nucleotide polymorphisms are provided. Methods for identifying subjects having a low or high drug metabolizing phenotype associated with CYP3A5 expression are provided. Assays, kits and methods for determining and assaying the CYP3A5 genotype and phenotype of individual patients are disclosed. Oligonucleotide probes and primers for use in the assays, kits and methods are described. Assays and methods for determining and evaluating an individual's metabolism of drugs and therapeutic agents, the potential for drug interactions, and thereby toxicity and effectiveness of certain drugs and treatment modalities, are provided.
    Type: Application
    Filed: November 22, 2005
    Publication date: May 25, 2006
    Inventors: Erin Schuetz, Jiong Zhang, Mahfoud Assem
  • Genotyping assay to predict CYP3A5 phenotype
    Patent number: 7022475
    Abstract: Genetic polymorphisms responsible or associated with altered expression of cytochrome P450 CYP3A5 enzyme are described. Single nucleotide polymorphisms are provided. Methods for identifying subjects having a low or high drug metabolizing phenotype associated with CYP3A5 expression are provided. Assays, kits and methods for determining and assaying the CYP3A5 genotype and phenotype of individual patients are disclosed. Oligonucleotide probes and primers for use in the assays, kits and methods are described. Assays and methods for determining and evaluating an individual's metabolism of drugs and therapeutic agents, the potential for drug interactions, and thereby toxicity and effectiveness of certain drugs and treatment modalities, are provided.
    Type: Grant
    Filed: October 10, 2001
    Date of Patent: April 4, 2006
    Assignee: St. Jude Children's Research Hospital
    Inventors: Erin Schuetz, Jiong Zhang, Mahfoud Assem
  • Genotyping assay to predict CYP3A5 phenotype
    Publication number: 20030143537
    Abstract: Genetic polymorphisms responsible or associated with altered expression of cytochrome P450 CYP3A5 enzyme are described. Single nucleotide polymorphisms are provided. Methods for identifying subjects having a low or high drug metabolizing phenotype associated with CYP3A5 expression are provided. Assays, kits and methods for determining and assaying the CYP3A5 genotype and phenotype of individual patients are disclosed. Oligonucleotide probes and primers for use in the assays, kits and methods are described. Assays and methods for determining and evaluating an individual's metabolism of drugs and therapeutic agents, the potential for drug interactions, and thereby toxicity and effectiveness of certain drugs and treatment modalities, are provided.
    Type: Application
    Filed: October 10, 2001
    Publication date: July 31, 2003
    Applicant: St. Jude Children's Research Hospital
    Inventors: Erin Schuetz, Jiong Zhang, Mahfoud Assem