Patents by Inventor Mahmoud Ghandi

Mahmoud Ghandi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • THERAPEUTIC TREATMENT OF MICROSATELLITE UNSTABLE CANCERS
    Publication number: 20220133693
    Abstract: The present disclosure relates to compositions and methods for the diagnosis and treatment or prevention of microsatellite unstable cancers. In particular, the instant disclosure provides for identification of a cancer as exhibiting microsatellite instability (MSI) and/or impaired mismatch repair (MMR), and selection and/or administration of an inhibitor of the WRN helicase as a therapeutic agent for such a cancer and/or subject having or at risk of developing such a cancer.
    Type: Application
    Filed: June 3, 2019
    Publication date: May 5, 2022
    Applicants: THE BROAD INSTITUTE, INC., DANA-FARBER CANCER INSTITUTE, INC., INSTITUTO CARLOS SLIM DE LA SALUD, A.C.
    Inventors: Francisca Vazquez, Adam Bass, Tsukasa Shibue, Edmond Chan, James McFarland, Mahmoud Ghandi, Aviad Tsherniak